Traumatic brain injury(TBI)is a significant public health issue,affecting approximately 1.7 million people annually in the United States alone,with over 5 million experiencing long-term disabilities(Roozenbeek et al.,...
financially supported by Ministerio de Ciencia e Innovación projects SAF2017-82736-C2-1-R to MTMF;in Universidad Autónoma de Madrid and by Fundación Universidad Francisco de Vitoria to JS;a predoctoral scholarship from Fundación Universidad Francisco de Vitoria;financial support from a 6-month contract from Universidad Autónoma de Madrid;a 3-month contract from the School of Medicine of Universidad Francisco de Vitoria。
Every year, around the world, between 250,000 and 500,000 people suffer a spinal cord injury(SCI). SCI is a devastating medical condition that arises from trauma or disease-induced damage to the spinal cord, disruptin...
supported by the Keio University Medical Science Fund(to YO);the General Insurance Association of Japan(to YK);the Takeda Science Foundation(to YK);grants from the Japan Agency for Medical Research and Development(AMED)(Grant JP24bm1123037 and JP24ym0126118)(to HO)。
Spinal cord injury(SCI)can cause motor and sensory paralysis,and autonomic nervous system disorders including malfunction of urination and defecation,thereby significantly impairing the quality of life.Researchers con...
FEDER Prostem Research Project,No.1510614(Wallonia DG06);the F.R.S.-FNRS Epiforce Project,No.T.0092.21;the F.R.S.-FNRS Cell Squeezer Project,No.J.0061.23;the F.R.S.-FNRS Optopattern Project,No.U.NO26.22;the Interreg MAT(T)ISSE Project,which is financially supported by Interreg France-Wallonie-Vlaanderen(Fonds Européen de Développement Régional,FEDER-ERDF);Programme Wallon d’Investissement Région Wallone pour les instruments d’imagerie(INSTIMAG UMONS#1910169);support from the European Research Council(ERC)under the European Union’s Horizon 2020 research and innovation programme(AdG grant agreement no.834317,Fueling Transport,PI Frédéric Saudou)。
Advanced microsystems in traumatic brain injury research:Traumatic brain injury(TBI)results from a mechanical insult to the brain,leading to neuronal and axonal damage and subsequently causing a secondary injury.Withi...
supported by the National Natural Science Foundation of China,Nos.82071307(to HL),82271362(to HL),82171294(to JW),82371303(to JW),and 82301460(to PX);the Natural Science Foundation of Jiangsu Province,No.BK20211552(to HL);Suzhou Medical Technology Innovation Project-Clinical Frontier,No.SKY2022002(to ZY);the Science and Education Foundation for Health of Suzhou for Youth,No.KJXW2023001(to XL)。
Differentiation of oligodendrocyte progenitor cells into mature myelin-forming oligodendrocytes contributes to remyelination.Failure of remyelination due to oligodendrocyte progenitor cell death can result in severe n...
funding support from the Canadian Institutes of Health Research;supported by a Doctoral Studentship from the Wings for Life Foundation。
Extensive neurodegeneration is a hallmark of traumatic spinal cord injury (SCI) that underlies permanent sensorimotor and autonomic impairments (Alizadeh et al.,2019).Following the primary impact,the spinal cord under...
supported by“la Caixa”Foundation(ID 100010434);FCT-Fundacao para a Ciência e a Tecnologia,I.P.under the agreement LCF/PR/HP20/52300001 and by FCT,I.P.,under projects PTDC/NAN-OPT/7989/2020,UIDB/04501/2020,UIDP/04501/2020,UIDB/04539/2020,UIDP/04539/2020 and LA/P/0058/2020 and through the individual grant SFRH/BD/139368/2018(DT)。
Functional recovery from central nervous system(CNS)trauma depends not only on axon regeneration or compensatory sprouting of uninjured fibers but also on the ability of newly grown axons to establish functional synap...
Antituberculosis drug-induced hepatotoxicity(ATDIH)is a significant concern while managing pediatric tuberculosis.There is limited data on pediatric ATDIH,and much of the management practices are extrapolated from adu...
Traumatic brain injury (TBI) is defined as damage to the brain resulting from an external sudden physical force or shock to the head.It is considered a silent public health epidemic causing significant death and disab...
supported by the National Natural Science Foundation of China,Nos.81871836(to MZ),82172554(to XH),and 81802249(to XH),81902301(to JW);the National Key R&D Program of China,Nos.2018YFC2001600(to JX)and 2018YFC2001604(to JX);Shanghai Rising Star Program,No.19QA1409000(to MZ);Shanghai Municipal Commission of Health and Family Planning,No.2018YQ02(to MZ);Shanghai Youth Top Talent Development Plan;Shanghai“Rising Stars of Medical Talent”Youth Development Program,No.RY411.19.01.10(to XH)。
Distinct brain remodeling has been found after different nerve reconstruction strategies,including motor representation of the affected limb.However,differences among reconstruction strategies at the brain network lev...