Spinal cord injury regenerative therapy development:integration of design of experiments  

作　　者：Yuji Okano Hideyuki Okano Yoshitaka Kase 

机构地区：[1]Division of CNS Regeneration and Drug Discovery,International Center for Brain Science(ICBS),Fujita Health University,Kutsukake-Cho,Toyoake-Shi,Aichi,Japan [2]Department of Extended Intelligence for Medicine,The Ishii-Ishibashi Laboratory,Keio University School of Medicine,Shinanomachi,Shinjuku-Ku,Tokyo,Japan [3]Keio University Regenerative Medicine Research Center,Kawasaki-ku,Kawasaki-shi,Japan

出　　处：《Neural Regeneration Research》2025年第9期2571-2573,共3页中国神经再生研究（英文版）

基　　金：supported by the Keio University Medical Science Fund(to YO);the General Insurance Association of Japan(to YK);the Takeda Science Foundation(to YK);grants from the Japan Agency for Medical Research and Development(AMED)(Grant JP24bm1123037 and JP24ym0126118)(to HO)。

摘　　要：Spinal cord injury(SCI)can cause motor and sensory paralysis,and autonomic nervous system disorders including malfunction of urination and defecation,thereby significantly impairing the quality of life.Researchers continue to explo re new stem cell strategies for the treatment of paralysis by transpla nting human induced pluripotent stem cell-derived neural ste m/progenitor cells(hiPSCNS/PCs)into spinal cord injured tissues.

关 键 词：SPINAL PARALYSIS INJURY 

分 类 号：R651.2[医药卫生—外科学]