financially supported by Ministerio de Ciencia e Innovación projects SAF2017-82736-C2-1-R to MTMF;in Universidad Autónoma de Madrid and by Fundación Universidad Francisco de Vitoria to JS;a predoctoral scholarship from Fundación Universidad Francisco de Vitoria;financial support from a 6-month contract from Universidad Autónoma de Madrid;a 3-month contract from the School of Medicine of Universidad Francisco de Vitoria。
Every year, around the world, between 250,000 and 500,000 people suffer a spinal cord injury(SCI). SCI is a devastating medical condition that arises from trauma or disease-induced damage to the spinal cord, disruptin...
supported by National Institute on Aging(NIH-NIA)R21 AG074152(to KMA);National Institute of Allergy and Infectious Diseases(NIAID)grant DP2 AI171150(to KMA);Department of Defense(DoD)grant AZ210089(to KMA)。
The brain's extracellular matrix(ECM),which is comprised of protein and glycosaminoglycan(GAG)scaffolds,constitutes 20%-40% of the human brain and is considered one of the largest influencers on brain cell functioning...
supported by the National Natural Science Foundation of China (No.32322020,32170676,31970646,32060152);the Natural Science Foundation of Heilongjiang Province,China (Key Program,No.ZD2023C007);Heilongjiang Touyan Innovation Team Program (China);the specific research fund of The Innovation Platform for Academicians of Hainan Province,China;the project supported by Hainan Province Clinical Medical Center (China).
Hepatocellular carcinoma(HCC)is one of the most common tumors with high prevalence and death rate,which lacks effective targeting and immunotherapy currently.Metabolic reprogramming,which provides an inherent advantag...
financially supported by the Career Development Fund(Grant No.C210112051)under the Agency for Science,Technology and Research(A*STAR)of Singapore;2022 MTC Young Individual Research Grants(Grant No:M22K3c0097)under Singapore Research,Innovation and Enterprise(RIE)2025 Plan,led by C Tan。
Tailoring thermal history during additive manufacturing(AM)offers a feasible approach to customise the microstructure and properties of materials without changing alloy compositions or post-heat treatment,which is gen...
National Key Research and Development Program of China(Nos.2022YFC2405100 and 2021YFC2401200);National Natural Science Foundation of China(No.81830033);Key R&D Program of Jiangsu Science and Technology Project(No.BE2022049);Key Research and Development Program of Henan Province(No.241111310100)
Deep brain stimulation(DBS)is a neurosurgical procedure that allows targeted circuit-based neuromodulation;it is also a standard of care for Parkinson’s disease(PD).[1]Postoperative DBS programming is a crucial step ...
NO RISK IS MORE TERRIFYING than that taken by the first root.A lucky root will eventually find water,but its first job is to anchor-to anchor an embryo and forever end its mobile phase,however passive that mobility wa...
supported by the Centre for Development of Advanced Computing (CDAC), Pune
In hilly regions,the existence of surface cracks in rock mass induces a potential threat to structural stability.Thus,the present research aims to explore the impact of surface cracks on the loadbearing capacity of st...
funded by the Key Project for Instrument Development Program-Ministry of Finance[Grant No.ZDYZ2012-3];Operational Support Project of Instrument Development-Chinese Academy of Sciences[Grant No.1187000169];Project of Automated Stem Cell Induction and Culture Instrument Development-Chinese Academy of Sciences[Grant No.1187000170];Scientific Instrument Development Program-Chinese Academy of Sciences[Grant Nos.ZDKYYQ20210006 and YJKYYQ20210042];Key Research Program of Chinese Academy of Sciences[Grant No.O2222001];Guangdong Basic and Applied Basic Research Foundation[Grant No.2022A1515110435];Guangzhou Basic and Applied Basic Research Project[Grant No.2023A04J0107];Project funded by China Postdoctoral Science Foundation[Grant No.2021M693192];Guangdong International Scientific Research Cooperation Project[Grant No.2022A0505050037];Science and Technology Planning Project of Guangdong Province[Grant No.2023B1212060050].
Somatic cell reprogramming generates induced pluripotent stem cells(iPSCs),which serve as a crucial source of seed cells for personalized disease modeling and treatment in regenerative medicine.However,the process of ...
financially supported by the National Natural Science Foundation of China (Nos.21805014,82102635,52373087,52003300 and 22109120);Chongqing Municipal Education Commission (Nos.CXQT20026 and KJQN202201408)。
Constructing self-protected metastable intermolecular composites(MICs) enables the regulation of microstructures towards boosting controllable detonation performance,and also prevents information leakage,which is mean...
supported by the National Key Research&Development Program of China(2021YFA1101000 and 2022YFC3401500);National Natural Science Foundation of China(82372688,92253203 and U22A20317);Leading Innovative and Entrepreneur Team Introduction Program of Zhejiang(2022R01002);Zhejiang Provincial Natural Science Foundation of China(LD22H300003)。
Tumorigenesis hinges on the reprogramming of cellular metabolisms to meet the requirements of intracellular biomass,characterized by the acquisition of nutrients from the environment as a common feature(Pavlova and Th...