IMMUNOTHERAPY

作品数:1708被引量:5784H指数:31
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相关领域:医药卫生更多>>
相关作者:孟庆翔李添应谷冬梅邱前辉韩虹更多>>
相关机构:空军军医大学中山大学中山大学附属第一医院华中科技大学更多>>
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相关基金:国家自然科学基金中国博士后科学基金国家重点基础研究发展计划广东省自然科学基金更多>>
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Recent advances in immunotherapy targeting amyloid-beta and tauopathies in Alzheimer’s disease
《Neural Regeneration Research》2026年第2期577-587,共11页Sha Sha Lina Ren Xiaona Xing Wanshu Guo Yan Wang Ying Li Yunpeng Cao Le Qu 
supported by the Nature Science Foundation of Liaoning Province,Nos.2022-MS-211,2021-MS-064,and 2024-MS-048(all to YC).
Alzheimer’s disease,a devastating neurodegenerative disorder,is characterized by progressive cognitive decline,primarily due to amyloid-beta protein deposition and tau protein phosphorylation.Effectively reducing the...
关键词:Alzheimer’s disease amyloid deposits AMYLOID-BETA antibody cognitive dysfunction dementia IMMUNOTHERAPY OLIGOMER preventive immunization tau hyperphosphorylation 
Integrated multi-omics characterization of neuroblastoma with bone or bone marrow metastasis
《Genes & Diseases》2025年第3期382-396,共15页Kai Huang Linyu Yang Yue Ma Lijian Cao Suwen Li Zhenzhen Zhao Jianwu Zhou Shan Wang 
supported in part by research grants from the Key Project of the National Key R&D Plan“Research on Prevention and Control of Major Chronic Non-Communicable Diseases”(China);the Ministry of Science and Technology of the People’s Republic of China,and the National Key R&D Program of China(No.2018YFC1313000,2018YFC1313004).
The pathogenesis of neuroblastoma with bone or bone marrow metastasis (NB-BBM)and its complex immune microenvironment remain poorly elucidated, hampering the advancement of effective risk prediction for BBM and limiti...
关键词:Bone marrow metastasis Bone metastasis IMMUNOTHERAPY Multi-omics NEUROBLASTOMA Transketolase(TKT) 
Risk of autoimmunity,cancer seeding,and adverse events in human trials of whole-tissue autologous therapeutic vaccines
《Cancer Pathogenesis and Therapy》2025年第2期129-134,共6页Garret Gianneschi Anthony Scolpino James Oleske 
Background:Whole-tissue autologous therapeutic vaccines(WATVs)are a form of cancer immunotherapy that use a patient's own pathological tissue.Concerns exist regarding the potential of WATVs to induce autoimmunity or t...
关键词:NEOPLASMS VACCINATION AUTOIMMUNITY IMMUNOTHERAPY Drug-related side effects and adverse reactions Systematic review Cancer vaccines 
Non-coding RNAs as potential mediators of resistance to lung cancer immunotherapy and chemotherapy
《Oncology Research》2025年第5期1033-1054,共22页JIAHUI WANG HONGCHENG GE ZHENGYUAN YU LINGZHI WU 
Lung cancer is a common cause of cancer-related death globally.The majority of lung cancer patients initially benefit from chemotherapy and immunotherapy.However,as the treatment cycle progresses and the disease evolv...
关键词:Non-coding RNAs(ncRNAs) Lung cancer Drug resistance IMMUNOTHERAPY CHEMOTHERAPY Immune checkpoints Immune escape 
Conversion treatment for advanced intrahepatic cholangiocarcinoma:Opportunities and challenges
《World Journal of Gastroenterology》2025年第15期24-41,共18页Jun-Jie Liu Mi Zhou Tong Yuan Zhi-Yong Huang Zun-Yi Zhang 
The prevalence of intrahepatic cholangiocarcinoma(ICC)is increasing globally.Despite advancements in comprehending this intricate malignancy and formulating novel therapeutic approaches over the past few decades,the p...
关键词:Intrahepatic cholangiocarcinoma Conversion treatment DOWNSTAGING Combination therapy Chemotherapy IMMUNOTHERAPY Locoregional therapies 
Cancer stem cell specificity as new targets in breast tumor treatment
《Oncology Research》2025年第4期811-819,共9页ZHIZHENG ZHANG TAO LI YUAN LI XI WANG HAO LIU XINYU SHEN ANN XU TIANSONG XIA BO XU 
supported by Jiangsu Province“333”Project(BRA2020380).
Background:Breast cancer is a prevalent malignant tumor affecting females,with treatment options including surgery,radiotherapy,chemotherapy,and endocrine therapy.Methods:This review synthesizes existing literature on...
关键词:Breast cancer Stem cells IMMUNOTHERAPY GENE 
Glucose metabolism perturbations influence tumor microenvironments via LINC01139 pathway and facilitate immunotherapy in hepatocellular carcinoma
《Genes & Diseases》2025年第2期48-51,共4页Yueying Gao Jinyang Yu Zhi Li Kefan Liu Jiwei Pan Ya Zhang Yanlin Ma Jiwei Zhang Zhigang Liu Yongsheng Li 
supported by the National Natural Science Foundation of China (No.32322020,32170676,31970646,32060152);the Natural Science Foundation of Heilongjiang Province,China (Key Program,No.ZD2023C007);Heilongjiang Touyan Innovation Team Program (China);the specific research fund of The Innovation Platform for Academicians of Hainan Province,China;the project supported by Hainan Province Clinical Medical Center (China).
Hepatocellular carcinoma(HCC)is one of the most common tumors with high prevalence and death rate,which lacks effective targeting and immunotherapy currently.Metabolic reprogramming,which provides an inherent advantag...
关键词:METABOLISM IMMUNOTHERAPY PROGRAMMING 
Quadruple therapy with immunotherapy and chemotherapy as firstline conversion treatment for unresectable advanced gastric adenocarcinoma: A case report
《World Journal of Gastrointestinal Oncology》2025年第4期503-514,共12页Xiao-Yu Du Ren-Jie Xia Li-Wen Shen Jian-Guo Ma Wei-Qing Yao Wei Xu Zhi-Peng Lin Liang-Bin Ma Guo-Qiang Niu Rui-Fang Fan Shu-Mei Xu Long Yan 
Supported by the Health Industry Research Program of Gansu Province,No.GSWSKY2021-043;the Youth Science and Technology Foundation of Gansu Province,No.22JR11RA002;the Natural Science Foundation of Gansu Province,No.22JR5RA008.
BACKGROUND The treatment of gastric cancer remains highly challenging,particularly in cases of unresectable locally advanced or metastatic disease.Although chemotherapy and immunotherapy have shown some efficacy in su...
关键词:Unresectable locally advanced gastric adenocarcinoma Conversion therapy IMMUNOTHERAPY Programmed cell death protein 1 inhibitors Sintilimab Case report 
Immune therapies in intermediate-advanced unresectable hepatocellular carcinoma: Changing the therapeutic landscape
《World Journal of Gastroenterology》2025年第14期1-5,共5页Sagnik Biswas Arghya Samanta 
Hepatocellular carcinoma(HCC)is one of the leading causes of cancer-related mortality worldwide.A substantial proportion of patients are diagnosed with advanced or intermediate-advanced stage disease at presentation a...
关键词:Intermediate-advanced stage hepatocellular carcinoma IMMUNOTHERAPY Tyrosine kinase inhibitors SORAFENIB 
Advances in immunotherapy and targeted therapy for pancreatic cancer
《Oncology and Translational Medicine》2025年第2期81-91,共11页Xiangyan Zhou Xiaohui Wang Shengli Yang Zaozao Huang 
Pancreatic cancer remains one of the most challenging malignancies to treat,with a poor prognosis and limited therapeutic options.Despite the success of immunotherapy and targeted therapies for other cancers,these app...
关键词:Pancreatic cancer IMMUNOTHERAPY Targeted therapies 
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