supported by Swiss Center for Applied Human Toxicology(SCAHT AP22-01)(to RN).
Alzheimer’s disease(AD)is the most common cause of dementia,characterized by progressive cognitive decline,and affects over 55 million people worldwide.AD is pathological featured by the aberrant accumulation of amyl...
Alzheimer’s disease(AD)is the most common form of dementia.In addition to the lack of effective treatments,there are limitations in diagnostic capabilities.The complexity of AD itself,together with a variety of other...
supported by a National Research Foundation of Korea (NRF) grant funded by the Korean government (2020M3E5D9079764, RS-2024-00408736)(to KS);supported by Korea Drug Development Fund funded by Ministry of Science and ICT,Ministry of Trade,Industry,and Energy,and Ministry of Health and Welfare (RS-2024-00335752)(to KS)。
The hippocampus is part of the brain limbic system and plays an important role in learning and memory.Moreover,its ability to form,consolidate,and retrieve different types of memories makes it a central component in t...
Alzheimer's disease and Down syndrome:Down syndrome(DS)is a genetic disorder caused by the presence of an extra complete or partial chromosome 21.Over the past few decades,significant advancements in medical treatment...
supported by a grant from the Japan Foundation for applied enzymology (to NT);the Grant-in-Aid for Scientific Research (C) from the Japan Society for the Promotion of Science (26430059, 17K08272, and 20K07014 to NT);the establishment of university fellowships toward the creation of science technology innovation (JPMJFS2128);a Grant-in-Aid for JSPS Fellows (23KJ1603)(to MK)。
The purpose of this perspective is to discuss the future development of a potential treatment of glial pathology in Alzheimer's disease(AD) and a new regulatory mechanism, nuclear lipids, which may be involved in the ...
With the advances in medicine and technology,life expectancy has increased significantly in recent decades.While this is positive news,it also brings major challenges to public health systems.As people live longer,the...
Alzheimer's disease (AD) is the most common form of dementia,affecting millions worldwide.It is cha racterized by progressive cognitive decline and changes in behavior and personality,attributed to neuropathological c...
supported by a New Investigator grant from the Alzheimer’s Society of Canada;research grant from Djavad Mowafaghian Centre for Brain Health to KSAE。
Alzheimer's disease (AD) is an age-related neurodegenerative disease that involves a progressive decline in memory,thinking,a nd learning.AD has been studied rigorously for more than 50 years yet there is a marked lac...
Pathological and clinical variability in Alzheimer's disease(AD):AD is clinically cha racterized by progressive memory loss and cognitive impairment.From a pathological point of view,the main features of AD are the de...
funded by U.S.Air Force Office of Scientific Research FA9550-21-1-0096,FONDAP program 15150012,ANID/FONDEF ID1ID22I10120,FONDECY/ANID 1220573;the US Army Medical Research Acquisition Activity(USAMRAA)project number AL2201415;DoD Award HT9425-23-1-0990,AL220141(to CH)。
Lifestyle and demographics of the world's population are causing serious health problems impacting the brain,increasing the incidence of Alzheimer's disease(AD)and other types of dementia.Although we have gained impor...