DISEASES

作品数：2150被引量：8037H指数：32
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Aerobic exercise–induced myokine irisin release:A novel strategy to promote neuroprotection and improve cognitive function
《Neural Regeneration Research》2026年第1期306-307,共2页Jae-Won Choi Rengasamy Balakrishnan 
supported by The Basic Science Research Program through the National Research Foundation of Korea(NRF);funded by the Ministry of Education(RS-2023-00244901)(to RB)。
Challenges in the prevention and treatment of mild cognitive impairment associated with Alzheimer's disease:Increased life expectancy due to advancements in medical care has given rise to an aging population,accompani...
关键词：PREVENTION DISEASES COGNITIVE 
Shedding light on the retina to see healthy and pathological aging
《Neural Regeneration Research》2025年第12期3537-3538,共2页Marília Inês Móvio Maria Camila Almeida Sergio T.Ferreira Alexandre Hiroaki Kihara 
With the advances in medicine and technology,life expectancy has increased significantly in recent decades.While this is positive news,it also brings major challenges to public health systems.As people live longer,the...
关键词：DISEASES ALZHEIMER cases 
Aptamers as new promising entities for therapeutics:our experience from the neurological diseases
《Neural Regeneration Research》2025年第12期3523-3524,共2页Macarena Hernández-Jiménez Fernando de Castro 
Based on data from Global Burden of Disease,Injuries,and Risk Factors(2024),disorders of the central nervous system(CNS)are an important cause of death or long-term disability,representing the top-ranked contributor t...
关键词：DISEASES CONGENITAL IMPAIRMENT 
LPAR3:a shared target for neurodegenerative diseases?
《Neural Regeneration Research》2025年第12期3527-3528,共2页Susan Acton Laurent Chesnel 
Neurodegenerative diseases are often studied in isolation due to the vast differences in their underlying causes,the diversity in neuron types affected,and the variations in their clinical symptoms.However,there are c...
关键词：DISEASES DEGENERATIVE 
Role of resident memory T cells in neuroinflammatory and neurodegenerative diseases in the central nervous system
《Neural Regeneration Research》2025年第11期3227-3228,共2页Kimitoshi Kimura 
The immune system has been attracting increasing attention in the field of chronic neurological disorders in the central nervous system(CNS).Autoreactive T cells targeting CNS antigens play a crucial role in the devel...
关键词：DISEASES DEGENERATIVE PATHOLOGY 
Beginning from the end:the presynaptic terminal as a pathomechanism hub in frontotemporal dementia and amyotrophic lateral sclerosis
《Neural Regeneration Research》2025年第11期3217-3218,共2页Laura Huggon Emma L.Clayton 
funded by a senior research fellowship from Alzheimer’s Research UK (ARUK-SRF2022A-005);funded by a PhD studentship from Alzheimer’s Society (571);supported by the UK Dementia Research Institute through UK DRI Ltd.;principally funded by the UK Medical Research Council
Frontotemporal dementia and amyotrophic lateral sclerosis:Frontotemporal dementia(F T D)and amyo t rophic lateral sclerosis(ALS)are neurodegenerative diseases with significant overlapping attributes.While these neurod...
关键词：DISEASES amyotrophic SCLEROSIS 
Small heat shock protein B8:from cell functions to its involvement in diseases and potential therapeutic applications被引量：1
《Neural Regeneration Research》2025年第10期2872-2886,共15页Marta Chierichetti Riccardo Cristofani Valeria Crippa Veronica Ferrari Marta Cozzi Elena Casarotto Paola Pramaggiore Laura Cornaggia Guglielmo Patelli Ali Mohamed Margherita Piccolella Mariarita Galbiati Paola Rusmini Barbara Tedesco Angelo Poletti 
supported by:Fondazione Telethon-Italy(No.GGP19128 to AP);Fondazione Cariplo-Italy(No.2021-1544 to RC);Fondazione Italiana di Ricerca per la Sclerosi Laterale Amiotrofica(AriSLA)-Italy(No.MLOpathy to AP;Target-RAN to AP);Association Française contre les Myopathies-France(AFM Telethon No.23236 to AP);Kennedy’s Disease Association-USA(2018 grant to RC;2020 grant to MG);Ministero dell’Universitàe della Ricerca(MIUR)-Italy(PRIN-Progetti di ricerca di interesse nazionale(No.2017F2A2C5 to AP;No.2022EFLFL8 to AP;No.2020PBS5MJ to VC;No.2022KSJZF5 to VC);PRIN-Progetti di ricerca di interesse nazionale-bando 2022,PNRR finanziato dall’Unione europea-Next Generation EU,componente M4C2,investimento 1.1(No.P2022B5J32 to RC and No.P20225R4Y5 to VC);CN3:RNA-Codice Proposta:CN_00000041;Tematica Sviluppo di terapia genica e farmaci con tecnologia a RNA(Centro Nazionale di Ricerca-CN3 National Center for Gene Therapy and Drugs based on RNA Technology to AP);Progetto Dipartimenti di Eccellenza(to DiSFeB);Ministero della Salute,Agenzia Italiana del Farmaco(AIFA)-Italy(Co_ALS to AP);Universitàdegli Studi di Milano(piano di sviluppo della ricerca(PSR)UNIMI-linea B(to RC and BT).
Heat shock protein family B(small)member 8(HSPB8)is a 22 kDa ubiquitously expressed protein belonging to the family of small heat shock proteins.HSPB8 is involved in various cellular mechanisms mainly related to prote...
关键词：AGGREGATION AUTOPHAGY cancer CHAPERONE chaperone-assisted selective autophagy cognitive impairment HSPB8 NEUROINFLAMMATION neuromuscular diseases therapy 
Developing mRNA Nanomedicines with Advanced Targeting Functions
《Nano-Micro Letters》2025年第7期53-106,共54页Ji Wang Lijun Cai Ning Li Zhiqiang Luo Haozhen Ren Bing Zhang Yuanjin Zhao 
supported by the National Key Research and Development Program of China(2022YFA1105304);the National Natural Science Foundation of China(T2225003 and 61927805);the Nanjing Medical Science and Technique Development Foundation(ZKX21019);the Clinical Trials from Nanjing Drum Tower Hospital(2022-LCYJ-ZD-01);the Jiangsu Funding Program for Excellent Postdoctoral Talent(2023ZB032);the Natural Science Foundation of Jiangsu Province(BK20240223);the Project of Institute of Chinese Medicine of Nanjing University(ICM2024011);the Aid Project of Nanjing Drum Tower Hospital Health,Education&Research Foundation.
The emerging messenger RNA(mRNA)nanomedicines have sprung up for disease treatment.Developing targeted mRNA nanomedicines has become a thrilling research hotspot in recent years,as they can be precisely delivered to s...
关键词：MRNA Delivery system Targeted therapy DISEASES Precision medicine 
Data-driven drug repositioning using olfactory omics profiles:challenges and perspectives in neurodegeneration
《Neural Regeneration Research》2025年第7期1997-1998,共2页Paz Cartas-Cejudo Adriana Cortés Mercedes Lachén-Montes Elena Anaya-Cubero Joaquín Fernández-Irigoyen Enrique Santamaría 
funded by grants from the Spanish Ministry of Science,Innovation and Universities(Ref.PID2019-110356RB-I00/AEI/10.13039/501100011033)to JFI and ES;the Department of Economic and Business Development from Government of Navarra(Ref.0011-1411-2023-000028 to ES);supported by a predoctoral fellowship from the Public University of Navarra(UPNA);supported by a postdoctoral fellowship from Miguel Servet Foundation-Navarrabiomed;supported by“Programa MRR Investigo 2023”in the framework of the European Union recovery and resilience facility。
Data-driven drug repositioning using olfactory omics profiles-challenges and perspectives in neurodegeneration:Neurodegenerative diseases are characterized by progressive degeneration and loss of neuronal function in ...
关键词：DISEASES drug AMYLOID 
Harnessing therapeutic potential of induced pluripotent stem cell–derived endothelial cells for remyelination in the central nervous system
《Neural Regeneration Research》2025年第6期1715-1716,共2页Dan Ma Nona Pop 
supported by a grant from Aston University,Birmingham,UK (to DM)。
Myelin is the protective sheath surrounding nerve fibers, and its damage(demyelination) occurs in many central nervous system(CNS) diseases, including multiple sclerosis(MS), traumatic injury, neurodegenerative diseas...
关键词：MYELIN protective DISEASES 
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