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DEGENERATIVE: 作品数：160被引量：390H指数：11; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：杨永宏郑杰楼肃亮张冬生钱金黔更多>>; 相关机构：解放军第一一七医院东南大学华中科技大学第三军医大学新桥医院更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划云南省自然科学基金以色列科学基金更多>>

LPAR3:a shared target for neurodegenerative diseases?: 《Neural Regeneration Research》2025年第12期3527-3528,共2页Susan Acton Laurent Chesnel; Neurodegenerative diseases are often studied in isolation due to the vast differences in their underlying causes,the diversity in neuron types affected,and the variations in their clinical symptoms.However,there are c...; 关键词：DISEASES DEGENERATIVE

Role of resident memory T cells in neuroinflammatory and neurodegenerative diseases in the central nervous system: 《Neural Regeneration Research》2025年第11期3227-3228,共2页Kimitoshi Kimura; The immune system has been attracting increasing attention in the field of chronic neurological disorders in the central nervous system(CNS).Autoreactive T cells targeting CNS antigens play a crucial role in the devel...; 关键词：DISEASES DEGENERATIVE PATHOLOGY

Immunoassay development guidelines for neurodegenerative disorders:lessons from a failed pS129-α-synuclein electrochemiluminescence immunoassay: 《Neural Regeneration Research》2025年第10期2906-2908,共3页Hash Brown Taha Alanna Morris; An aging population is a double-edged sword.On one hand,advancements in biotechnology and healthcare allow more people to enjoy longer lives.On the other hand,increases in the aging population accompany a surge in age...; 关键词：AGING DEGENERATIVE necessarily

Peripheral blood RNA biomarkers can predict lesion severity in degenerative cervical myelopathy: 《Neural Regeneration Research》2025年第6期1764-1775,共12页Zhenzhong Zheng Jialin Chen Jinghong Xu Bin Jiang Lei Li Yawei Li Yuliang Dai Bing Wang; supported by Hunan Provincial Key Research and Development Program,No.2021SK2002(to BW);the Natural Science Foundation of Hunan Province of China(General Program),No.2021JJ30938(to YL)。; Degenerative cervical myelopathy is a common cause of spinal cord injury,with longer symptom duration and higher myelopathy severity indicating a worse prognosis.While numerous studies have investigated serological bi...; 关键词：biomarkers candidate genes degenerative cervical myelopathy gene expression analysis immune cell types neurological disabilities peripheral blood RNA profiles spinal cord injury

Microglial dysfunction and genetic risk for neurodegenerative disease: 《Neural Regeneration Research》2025年第5期1401-1402,共2页Debra S.MacDonald Jay Penney; supported by a Canada Research Chair award to JP。; Neurodegenerative disorders such as Alzheimer's and Parkinson's diseases a re increasing in prevalence as world populations age.While tremendous progress has been made,our understanding of the mechanisms that underlie...; 关键词：DEGENERATIVE DISEASES

Ischemia-reperfusion injury after spinal cord decompressive surgery-An in vivo rat model: 《Animal Models and Experimental Medicine》2025年第3期405-420,共16页Boyu Zhang Zhefeng Jin Pengren Luo He Yin Xin Chen Bowen Yang Xiaokuan Qin LiGuo Zhu Bo Xu Guoliang Ma Dian Zhang; Wangjing Hospital Affiliated to China Academy of Chinese Medical Sciences,Grant/Award Number:WJYY-YJKT-2022-13。; Background:Although decompression surgery is the optimal treatment for patients with severe degenerative cervical myelopathy(DCM),some individuals experience no improvement or even a decline in neurological function a...; 关键词：8-oxoG DNA degenerative cervical myelopathy spinal cord ischemia-reperfusion injury surgical decompression

Mitochondrial therapeutics and mitochondrial transfer for neurodegenerative diseases and aging: 《Neural Regeneration Research》2025年第3期794-796,共3页Neville Ng Michelle Newbery Nicole Miles Lezanne Ooi; supported by a MAWA Project Grant(to NN,MN,LO)。; Mitochondrial dysfunction and neurodegeneration:Progressive neurodegenerative diseases affect a significant proportion of the population;in a single year,there are as many as 276 million disabilities and 9 million dea...; 关键词：DEGENERATIVE DISEASES MITOCHONDRIAL

Crocus sativus(Saffron): A potential multifunctional therapeutic agent for neurodegenerative disorders: 《Journal of Biomedical Research》2025年第1期114-116,共3页Yours Sincerely Mohammad Reza Khazdair; Dear Editor,Neurodegenerative disorders (NDDs) are agerelated disorders characterized by the deposition of abnormal forms of proteins or the progressive loss of neurons in the brain.NDDs are classified according to th...; 关键词：DISORDERS DEGENERATIVE doses

Assessment of bone strength and fracture behavior of degenerative vertebrae through quantifying morphology and density distribution: 《Acta Mechanica Sinica》2025年第1期211-225,共15页Meng Zhang He Gong Ming Zhang; supported by the National Natural Science Foundation of China(Grant No.12272029).; Lumbar degeneration leads to changes in geometry and density distribution of vertebrae,which could further influence the mechanical property and behavior.This study aimed to quantitatively describe the variations in s...; 关键词：Statistical shape model Statistical appearance model Lumbar degeneration Compressive strength Fracture behavior

Insights into the underlying pathogenesis and therapeutic potential of endoplasmic reticulum stress in degenerative musculoskeletal diseases: 《Military Medical Research》2024年第6期839-862,共24页Ze-Qin Wen Jun Lin Wen-Qing Xie Yun-Han Shan Ge-Hua Zhen Yu-Sheng Li; supported by the National Natural Science Foundation of China(92268115,82072506,81874030,82172387,82372371,82371989);the Science and Technology Innovation Program of Hunan Province(2021RC3025);the Natural Science Foundation of Jiangsu Province(BK20230066);the Suzhou Science and Technology Development Plan(SKY2023035,SZM2023008);the Gusu Health Talents Program(GSWS2020023);the Innovation Project for Postgraduate Students of Central South University(1053320221391,1053320231273).; Degenerative musculoskeletal diseases are structural and functional failures of the musculoskeletal system,including osteoarthritis,osteoporosis,intervertebral disc degeneration(IVDD),and sarcopenia.As the global popu...; 关键词：Endoplasmic reticulum stress Degenerative musculoskeletal diseases PATHOGENESIS TREATMENT

DEGENERATIVE