Crocus sativus(Saffron): A potential multifunctional therapeutic agent for neurodegenerative disorders  

作　　者：Yours Sincerely Mohammad Reza Khazdair 

机构地区：[1]Pharmaceutical Science and Clinical Physiology,Cardiovascular Diseases Research Center,Birjand University of Medical Sciences,Birjand,South Khorasan 9717853111,Iran

出　　处：《Journal of Biomedical Research》2025年第1期114-116,共3页生物医学研究杂志(英文版)

摘　　要：Dear Editor,Neurodegenerative disorders (NDDs) are agerelated disorders characterized by the deposition of abnormal forms of proteins or the progressive loss of neurons in the brain.NDDs are classified according to their pathophysiological properties,including cognitive dysfunction,Alzheimer's disease (AD) and other dementias,Parkinson's disease,and motor neuron disease.The increased oxidative stress and neuro-inflammatory events contribute to neuronal atrophy and death in NDDs~([1]).Nitric oxide in the central nervous system has several functions,including the regulation of synaptic plasticity and neurosecretion.The physiological amount of nitric oxide is neuroprotective,whereas higher doses are noticeably neurotoxic~([2]).

关 键 词：DISORDERS DEGENERATIVE doses 

分 类 号：R285[医药卫生—中药学]