AGING

作品数:1591被引量:5252H指数:22
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相关作者:杨睿于建徐朗莱王博涵郭岩更多>>
相关机构:清华大学中南大学东南大学北京大学更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划国家高技术研究发展计划北京市自然科学基金更多>>
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Alpha-synuclein-induced upregulation of SKI family transcriptional corepressor 1: A new player in aging and Parkinson's disease?
《Neural Regeneration Research》2026年第1期320-321,共2页Lauren Barrett Rebekah Bevans Aideen M.Sullivan Louise M.Collins Gerard W.O’Keeffe 
supported by Science Foundation Ireland (Grant 19/FFP/6666),Cure Parkinson’s (Grant CP:GO01);a PhD studentship from the Anatomical Society。
SKI family transcriptional corepressor 1(SKOR1also known as LbxCor1, Fussel15, or CORL1), is a member of the SKI family of proteins and is transcribed from a protein-coding gene located on chromosome 15 in humans, tha...
关键词:Alpha Cor AGING 
Proteostasis failure:at the intersection between aging and Alzheimer's disease
《Neural Regeneration Research》2025年第11期3221-3222,共2页Natalia Poblete Claudio Hetz 
funded by U.S.Air Force Office of Scientific Research FA9550-21-1-0096,FONDAP program 15150012,ANID/FONDEF ID1ID22I10120,FONDECY/ANID 1220573;the US Army Medical Research Acquisition Activity(USAMRAA)project number AL2201415;DoD Award HT9425-23-1-0990,AL220141(to CH)。
Lifestyle and demographics of the world's population are causing serious health problems impacting the brain,increasing the incidence of Alzheimer's disease(AD)and other types of dementia.Although we have gained impor...
关键词:ALZHEIMER AMYLOID STASIS 
Sex differences in aging and injured brain
《Neural Regeneration Research》2025年第10期2901-2902,共2页Jordan N.Williamson Yuan Yang 
supported by NIH/NICHD RO1HD109157;supported by his American Heart AssociationAward Career Development Award (932980);National Science Foundation CAREER award (NSF2401215)
Background:The prevalence,age of onset,and symptomatology of traumatic brain injury,stroke,and neurodegenerative diseases(such as Alzheimer’s disease(AD),Parkinson’s disease,amyotrophic lateral sclerosis,and Hunting...
关键词:HUNTINGTON PREVALENCE TRAUMATIC 
Immunoassay development guidelines for neurodegenerative disorders:lessons from a failed pS129-α-synuclein electrochemiluminescence immunoassay
《Neural Regeneration Research》2025年第10期2906-2908,共3页Hash Brown Taha Alanna Morris 
An aging population is a double-edged sword.On one hand,advancements in biotechnology and healthcare allow more people to enjoy longer lives.On the other hand,increases in the aging population accompany a surge in age...
关键词:AGING DEGENERATIVE necessarily 
Biological and translational attributes of mitochondrial DNA copy number:Laboratory perspective to clinical relevance
《World Journal of Methodology》2025年第3期38-55,共18页Deepak Parchwani Ragini Singh Digisha Patel 
The mitochondrial DNA copy number(mtDNAcn)plays a vital role in cellular energy metabolism and mitochondrial health.As mitochondria are responsible for adenosine triphosphate production through oxidative phosphorylati...
关键词:Mitochondrial DNA copy number Mitochondrial DNA Quantitative polymerase chain reaction Cancer Neurodegenerative disease AGING 
Non-Musicians Experience Early Aging in Speech Perception in Noise Abilities Compared to Musicians
《Journal of Otology》2025年第2期133-140,共8页Kruthika.S. Ajith Kumar Uppunda 
Background:Research has shown that musicians outperform non-musicians in speech perception in noise(SPiN)tasks.However,it remains unclear whether the advantages of musical training are substantial enough to slow down ...
关键词:Music training Age effects Speech Perception in Noise Signal to Noise Ratio Speech Identification Scores 
Dendritic spine degeneration:a primary mechanism in the aging process
《Neural Regeneration Research》2025年第6期1696-1698,共3页Gonzalo Flores Leonardo Aguilar-Hernández Fernado García-Dolores Humberto Nicolini Andrea Judith Vázquez-Hernández Hiram Tendilla-Beltrán 
funded by CONAHCYT grant(252808)to GF;CONAHCYT’s“Estancias Posdoctorales por México”program(662350)to HTB。
Recent reports suggest that aging is not solely a physiological process in living beings;instead, it should be considered a pathological process or disease(Amorim et al., 2022). Consequently, this process involves a w...
关键词:AGING PROCESS STRESS 
Decline and fall of aging astrocytes:the human perspective
《Neural Regeneration Research》2025年第6期1713-1714,共2页Alexei Verkhratsky Alexey Semyanov 
“Last scene of all that ends this strange,eventful history,is second childishness and mere oblivion.I am sans teeth,sans eyes,sans taste,sans everything.”William Shakespeare‘As You Like It'Act 2,Sc.7,l.139Aging of ...
关键词:AGING teeth PROGRESSIVE 
Investigation of oxidative potential of fresh and O_(3)-aging PM_(2.5)from various emission sources across urban and rural regions
《Journal of Environmental Sciences》2025年第5期608-615,共8页Shuaishuai Ma Dongsheng Cheng Yingying Tang Younuo Fan Qiong Li Chengxiang He Zhiqing Zhao Tianyou Xu 
supported by the National Natural Science Foundation of China(No.42305109);Quzhou Municipal Science and Technology Bureau(No.2023K222).
Inhalation of atmospheric PM_(2.5)can induce the generation of excessive reactive oxygen species(ROS)in human alveoli,triggering local and systemic inflammation,which can directly or indirectly result in respiratory a...
关键词:Atmospheric PM_(2.5) Oxidative potential Emission sources DTT assay O_(3)aging 
L-arginine from elder human mesenchymal stem cells induces angiogenesis and enhances therapeutic effects on ischemic heart diseases
《World Journal of Stem Cells》2025年第4期79-98,共20页Jian-Zhong Li Xu Zhan Hao-Bo Sun Chao Chi Guo-Fu Zhang Dong-Hui Liu Wen-Xi Zhang Li-Hua Sun Kai Kang 
Supported by the National Natural Science Foundation of China,No.82472147;the Key Research and Development Program of Heilongjiang Province of China,No.2023ZX06C04;the Open Fund of Key Laboratory of Hepatosplenic Surgery,Ministry of Education,Harbin,China,No.GPKF202402.
BACKGROUND Mesenchymal stem cell(MSC)-based therapy may be a future treatment for myocardial infarction(MI).However,few studies have assessed the therapeutic efficacy of adipose tissue-derived MSCs(ADSCs)obtained from...
关键词:Adipose tissue-derived mesenchymal stem cells Bone marrow-derived mesenchymal stem cells L-ARGININE METABOLIC ANGIOGENESIS AGING 
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