supported by Science Foundation Ireland (Grant 19/FFP/6666),Cure Parkinson’s (Grant CP:GO01);a PhD studentship from the Anatomical Society。
SKI family transcriptional corepressor 1(SKOR1also known as LbxCor1, Fussel15, or CORL1), is a member of the SKI family of proteins and is transcribed from a protein-coding gene located on chromosome 15 in humans, tha...
funded by U.S.Air Force Office of Scientific Research FA9550-21-1-0096,FONDAP program 15150012,ANID/FONDEF ID1ID22I10120,FONDECY/ANID 1220573;the US Army Medical Research Acquisition Activity(USAMRAA)project number AL2201415;DoD Award HT9425-23-1-0990,AL220141(to CH)。
Lifestyle and demographics of the world's population are causing serious health problems impacting the brain,increasing the incidence of Alzheimer's disease(AD)and other types of dementia.Although we have gained impor...
supported by NIH/NICHD RO1HD109157;supported by his American Heart AssociationAward Career Development Award (932980);National Science Foundation CAREER award (NSF2401215)
Background:The prevalence,age of onset,and symptomatology of traumatic brain injury,stroke,and neurodegenerative diseases(such as Alzheimer’s disease(AD),Parkinson’s disease,amyotrophic lateral sclerosis,and Hunting...
An aging population is a double-edged sword.On one hand,advancements in biotechnology and healthcare allow more people to enjoy longer lives.On the other hand,increases in the aging population accompany a surge in age...
The mitochondrial DNA copy number(mtDNAcn)plays a vital role in cellular energy metabolism and mitochondrial health.As mitochondria are responsible for adenosine triphosphate production through oxidative phosphorylati...
Background:Research has shown that musicians outperform non-musicians in speech perception in noise(SPiN)tasks.However,it remains unclear whether the advantages of musical training are substantial enough to slow down ...
funded by CONAHCYT grant(252808)to GF;CONAHCYT’s“Estancias Posdoctorales por México”program(662350)to HTB。
Recent reports suggest that aging is not solely a physiological process in living beings;instead, it should be considered a pathological process or disease(Amorim et al., 2022). Consequently, this process involves a w...
“Last scene of all that ends this strange,eventful history,is second childishness and mere oblivion.I am sans teeth,sans eyes,sans taste,sans everything.”William Shakespeare‘As You Like It'Act 2,Sc.7,l.139Aging of ...
supported by the National Natural Science Foundation of China(No.42305109);Quzhou Municipal Science and Technology Bureau(No.2023K222).
Inhalation of atmospheric PM_(2.5)can induce the generation of excessive reactive oxygen species(ROS)in human alveoli,triggering local and systemic inflammation,which can directly or indirectly result in respiratory a...
Supported by the National Natural Science Foundation of China,No.82472147;the Key Research and Development Program of Heilongjiang Province of China,No.2023ZX06C04;the Open Fund of Key Laboratory of Hepatosplenic Surgery,Ministry of Education,Harbin,China,No.GPKF202402.
BACKGROUND Mesenchymal stem cell(MSC)-based therapy may be a future treatment for myocardial infarction(MI).However,few studies have assessed the therapeutic efficacy of adipose tissue-derived MSCs(ADSCs)obtained from...