ANGIOGENESIS

作品数：1155被引量：5085H指数：26
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相关领域：医药卫生生物学更多>>
相关作者：许建华芮泽郭刚王德峰李若谷更多>>
相关机构：北京大学中南大学四川大学温州医科大学更多>>
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相关基金：国家自然科学基金国家重点基础研究发展计划广东省自然科学基金中国博士后科学基金更多>>
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Sox2-overexpressing neural stem cells alleviate ventricular enlargement and neurological dysfunction in posthemorrhagic hydrocephalus
《Neural Regeneration Research》2026年第2期769-779,共11页Baocheng Gao Haoxiang Wang Shuang Hu Kunhong Zhong Xiaoyin Liu Ziang Deng Yuanyou Li Aiping Tong Liangxue Zhou 
supported by the National Natural Science Foundation of China,Nos.82473334(to LZ),82401629(to XL);the Major Scientific and Technological Achievements Transformation Project of Ningxia Hui Autonomous Region,No.2022CJE09013(to LZ);Mianyang Science and Technology Bureau(Mianyang Science and Technology Program),No.2023ZYDF097(to LZ);NHC Key Laboratory of Nuclear Technology Medical Transformation(Mianyang Central Hospital),No.2023HYX001(to LZ);Spinal Cord Diseases Clinical Medical Center of Yunnan Province,No.2024JSKFKT-16(to BG);the Natural Science Foundation of Sichuan Province,No.2024NSFSC1646(to XL);the China Postdoctoral Science Foundation,Nos.GZC20231811(to XL),2024T170601(to XL)and 2024M76228(to XL).
Neural stem cells(NSCs)have the potential for self-renewal and multidirectional differentiation,and their transplantation has achieved good efficacy in a variety of diseases.However,only 1%-10%of transplanted NSCs sur...
关键词：ANGIOGENESIS cerebrospinal fluid hippocampal transplantation inflammation MICROGLIA neural stem cells NEUROGENESIS posthemorrhagic hydrocephalus retinoic acid ^(Sox2) 
Microglia overexpressing brain-derived neurotrophic factor promote vascular repair and functional recovery in mice after spinal cord injury
《Neural Regeneration Research》2026年第1期365-376,共12页Fanzhuo Zeng Yuxin Li Xiaoyu Li Xinyang Gu Yue Cao Shuai Cheng He Tian Rongcheng Mei Xifan Mei 
supported by the National Natural Science Foundation of China,Nos.82072165 and 82272256(both to XM);the Key Project of Xiangyang Central Hospital,No.2023YZ03(to RM)。
Spinal cord injury represents a severe form of central nervous system trauma for which effective treatments remain limited.Microglia is the resident immune cells of the central nervous system,play a critical role in s...
关键词：ANGIOGENESIS apoptosis brain-derived neurotrophic factor colony stimulating factor 1 receptor inflammation MICROGLIA motor function spinal cord injury vascular endothelial growth factor 
Telencephalic stab wound injury induces regenerative angiogenesis and neurogenesis in zebrafish:unveiling the role of vascular endothelial growth factor signaling and microglia
《Neural Regeneration Research》2025年第10期2938-2954,共17页Danielle Fernezelian Philippe Rondeau Laura Gence Nicolas Diotel 
supported by European Regional Development Funds RE0022527 ZEBRATOX(EU-Région Réunion-French State national counterpart,to Nicolas Diotel and Jean-Loup Bascands).
After brain damage,regenerative angiogenesis and neurogenesis have been shown to occur simultaneously in mammals,suggesting a close link between these processes.However,the mechanisms by which these processes interact...
关键词：ANGIOGENESIS cerebral damage inflammation NEUROGENESIS stab wound TELENCEPHALON vascular endothelial growth factor ZEBRAFISH 
Generation of brain vascular heterogeneity:recent advances from the perspective of angiogenesis
《Neural Regeneration Research》2025年第7期2013-2014,共2页Nathanael J.Lee Ryota L.Matsuoka 
supported by funding from the National Institutes of Health(R01 NS117510)(to RLM)。
Heterogeneous proper t i es of vascular endothelial cells in the brain:The brain displays large energy dynamics and consumption,and this high level of metabolic demands is fulfilled by a continuous supply of glucose a...
关键词：ANGIOGENESIS HOMEOSTASIS network 
The crosstalk between non-coding RNAs and oxidative stress in cancer progression
《Genes & Diseases》2025年第3期146-167,共22页Qiqi Sun Xiaoyong Lei Xiaoyan Yang 
funded by the Hengyang City Science and Technology Planning Project(Hunan,China)(No.202150063473);the Scientific Research Project of Hunan Provincial Health Commission(China)(No.202202044140);the Scientific Research Project of Hunan Provincial Education Department(China)(No.21B0438).
As living standards elevate,cancers are appearing in growing numbers among younger individuals globally and these risks escalate with advancing years.One of the reasons is that instability in the cancer genome reduces...
关键词：ANGIOGENESIS Autophagy CANCER Cancer energy metabolism Epithelial mesenchymal transformation Non-coding RNAs Oxidative stress 
Therapeutic potential of integrins in diabetic retinopathy
《World Journal of Diabetes》2025年第5期109-118,共10页Li-Mei He Sarul Borjigin Xin-Qi Chen Zhao-Li Yan Ming-Jie Wang 
Supported by the Natural Science Foundation of Inner Mongolia,No.2022MS08057;2022 Autonomous Region Medical and Health Science and Technology Plan Projects,No.202202190.
Diabetic retinopathy(DR),a leading cause of visual loss,is the result of microvascular damage induced by prolonged hyperglycemia.Numerous studies have revealed the pivotal role of integrins in the pathogenesis of DR,p...
关键词：Diabetic retinopathy INTEGRIN INFLAMMATION Microvascular permeability Microthrombus formation ANGIOGENESIS Integrin inhibitor 
Impact of SLC16A8 on tumor microenvironment and angiogenesis in colorectal cancer: New therapeutic target insights
《World Journal of Gastrointestinal Oncology》2025年第4期300-317,共18页Hong-Peng Tian Zhong-Xiang Xiao Bo-Wen Su Yi-Xuan Li Hong Peng Chang-Yuan Meng 
Supported by Nanchong Science and Technology Plan Project,No.23JCYJPT0064;Project of Sichuan Provincial Administration of Traditional Chinese Medicine,No.2024MS590。
BACKGROUND SLC16A8,a lactate efflux transporter,is upregulated in various cancers,but its effects on tumor microenvironments remain understudied.This research explores its role in colorectal cancer(CRC)and the impact ...
关键词：SLC16A8 Colorectal cancer HYPOXIA GLYCOLYSIS ANGIOGENESIS 
L-arginine from elder human mesenchymal stem cells induces angiogenesis and enhances therapeutic effects on ischemic heart diseases
《World Journal of Stem Cells》2025年第4期79-98,共20页Jian-Zhong Li Xu Zhan Hao-Bo Sun Chao Chi Guo-Fu Zhang Dong-Hui Liu Wen-Xi Zhang Li-Hua Sun Kai Kang 
Supported by the National Natural Science Foundation of China,No.82472147;the Key Research and Development Program of Heilongjiang Province of China,No.2023ZX06C04;the Open Fund of Key Laboratory of Hepatosplenic Surgery,Ministry of Education,Harbin,China,No.GPKF202402.
BACKGROUND Mesenchymal stem cell(MSC)-based therapy may be a future treatment for myocardial infarction(MI).However,few studies have assessed the therapeutic efficacy of adipose tissue-derived MSCs(ADSCs)obtained from...
关键词：Adipose tissue-derived mesenchymal stem cells Bone marrow-derived mesenchymal stem cells L-ARGININE METABOLIC ANGIOGENESIS AGING 
Dl-3-n-butylphthalide ameliorates diabetic foot ulcer by inhibiting apoptosis and promoting angiogenesis
《World Journal of Diabetes》2025年第4期252-269,共18页Wu-Han Wei Yuan-Ling Bai Dong Zhu Jing-Yu Zhang Qi-Chuan Yin Qiang Li Cai-Qi Shen Pei-Sheng Jin 
Supported by General Project of Xuzhou Science and Technology Bureau,No.KC22070.
BACKGROUND Diabetic foot ulcers(DFU)are estimated to affect about 18.6 million people worldwide annually.The pathogenesis of DFU is complex,and the available drugs are not effective.Dl-3-n-butylphthalide(NBP)is a synt...
关键词：Dl-3-n-butylphthalide Diabetic foot ulcer Network pharmacology ANGIOGENESIS APOPTOSIS 
Reactive oxygen species mediate ovarian cancer development,platinum resistance,and angiogenesis via CXCL8 and GSK-3β/p70S6K1 axis
《Genes & Diseases》2025年第2期133-135,共3页Jiange Qiu Qing Xu Tahira Panah A K M Helal Morshed Xue Wang Fengmei Zhou Wenjing Liu Jufeng Wang Ye Zhang Bingjie Liu Bing-Hua Jiang 
supported by the National Natural Science Foundation of China (No.81903174,82073393);the Provincial Health Commission of Henan,China (No.SBGJ202003013,LHGJ20190656);the Medical Science and Technology Research Plan Provincial Co-construction Project of Henan Province,China (No.SBGJ202302023);the Medical Science and Technology Project of Henan Province,China (No.SB201901110).
Ovarian cancer is one of the leading causes of cancerrelated deaths in women worldwide,with a five-year overall survival rate of less than 50%or30%if it is in the advanced stages.1 Reactive oxygen species(ROS)are typi...
关键词：ANGIOGENESIS cancer PLATINUM 
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