NEUROGENESIS

作品数：326被引量：1147H指数：15
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相关机构：南京医科大学浙江大学医学院附属第二医院天津医科大学总医院安徽师范大学更多>>
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FIREproof:Intricacies of microglial biology
《Neural Regeneration Research》2026年第2期663-664,共2页Wei Cao 
funded by NIH grants HL154720-03S1,AG057587,AG074283,DK122708-03S1,BrightFocus ADR A20183775,and Brown Foundation 2020 Healthy Aging Initiative(to WC).
Microglia are the macrophages that populate the brain parenchyma.Research in the past decades has identified them as both essential guardians of the brain and significant contributors to various neurological diseases....
关键词：neurological diseases facilitating neurogenesis debris removal central nervous systemincluding NEUROGENESIS MYELINATION synapse pruning brain 
Sox2-overexpressing neural stem cells alleviate ventricular enlargement and neurological dysfunction in posthemorrhagic hydrocephalus
《Neural Regeneration Research》2026年第2期769-779,共11页Baocheng Gao Haoxiang Wang Shuang Hu Kunhong Zhong Xiaoyin Liu Ziang Deng Yuanyou Li Aiping Tong Liangxue Zhou 
supported by the National Natural Science Foundation of China,Nos.82473334(to LZ),82401629(to XL);the Major Scientific and Technological Achievements Transformation Project of Ningxia Hui Autonomous Region,No.2022CJE09013(to LZ);Mianyang Science and Technology Bureau(Mianyang Science and Technology Program),No.2023ZYDF097(to LZ);NHC Key Laboratory of Nuclear Technology Medical Transformation(Mianyang Central Hospital),No.2023HYX001(to LZ);Spinal Cord Diseases Clinical Medical Center of Yunnan Province,No.2024JSKFKT-16(to BG);the Natural Science Foundation of Sichuan Province,No.2024NSFSC1646(to XL);the China Postdoctoral Science Foundation,Nos.GZC20231811(to XL),2024T170601(to XL)and 2024M76228(to XL).
Neural stem cells(NSCs)have the potential for self-renewal and multidirectional differentiation,and their transplantation has achieved good efficacy in a variety of diseases.However,only 1%-10%of transplanted NSCs sur...
关键词：ANGIOGENESIS cerebrospinal fluid hippocampal transplantation inflammation MICROGLIA neural stem cells NEUROGENESIS posthemorrhagic hydrocephalus retinoic acid ^(Sox2) 
Current understanding and prospects for targeting neurogenesis in the treatment of cognitive impairment
《Neural Regeneration Research》2026年第1期141-155,共15页Ye Liu Xibing Ding Shushan Jia Xiyao Gu 
supported by Technological Innovation 2030-Major Projects of“Brain Science and Brain-like Research,”No.2022ZD0206200(to XG);the National Natural Science Foundation of China,No.82371245(to SJ),82102246(to XD),81701092(to XG);the Natural Science Foundation of Shandong Province,No.ZR2020MH129(to SJ);Shanghai Municipal Key Clinical Specialty,No.shslczdzk03601;Shanghai Engineering Research Center of Peri-operative Organ Support and Function Preservation,No.20DZ2254200。
Adult hippocampal neurogenesis is linked to memory formation in the adult brain,with new neurons in the hippocampus exhibiting greater plasticity during their immature stages compared to mature neurons.Abnormal adult ...
关键词：aging Alzheimer's disease cerebrovascular diseases cognitive impairment energy metabolism HIPPOCAMPUS immune mechanisms NEUROGENESIS pathological states TREATMENT 
Enhanced neurogenesis after ischemic stroke:The interplay between endogenous and exogenous stem cells
《Neural Regeneration Research》2026年第1期212-223,共12页Ruxu Geng Yuhe Wang Renzhi Wang Jun Wu Xinjie Bao 
supported by the National Key Research and Development Program of China,No.2018YFA0108602;the CAMS Initiative for Innovative Medicine,No.2021-1-I2M-019;National High-Level Hospital Clinical Research Funding,No.2022-PUMCH-C-042(all to XB)。
Ischemic stroke is a significant global health crisis,frequently resulting in disability or death,with limited therapeutic interventions available.Although various intrinsic reparative processes are initiated within t...
关键词：brain-derived neurotrophic factor endogenous neuroregeneration exosomes hydrogels ischemic stroke mesenchymal stem cells neural stem cells NEUROGENESIS stem cell transplantation 
Activation of adult endogenous neurogenesis by a hyaluronic acid collagen gel containing basic fibroblast growth factor promotes remodeling and functional recovery of the injured cerebral cortex
《Neural Regeneration Research》2025年第10期2923-2937,共15页Yan Li Peng Hao Hongmei Duan Fei Hao Wen Zhao Yudan Gao Zhaoyang Yang Kwok-Fai So Xiaoguang Li 
supported by the National Natural Science Foundation of China,Nos.82272171(to ZY),82271403(to XL),81941011(to XL),31971279(to ZY),31730030(to XL);the Natural Science Foundation of Beijing,No.7222004(to HD).
The presence of endogenous neural stem/progenitor cells in the adult mammalian brain suggests that the central nervous system can be repaired and regenerated after injury.However,whether it is possible to stimulate ne...
关键词：adult endogenous neurogenesis basic fibroblast growth factor-hyaluronic acid collagen gel cortical remodeling functional recovery migration motor cortex injury neural circuits neural stem cells newborn neurons proliferation 
Telencephalic stab wound injury induces regenerative angiogenesis and neurogenesis in zebrafish:unveiling the role of vascular endothelial growth factor signaling and microglia
《Neural Regeneration Research》2025年第10期2938-2954,共17页Danielle Fernezelian Philippe Rondeau Laura Gence Nicolas Diotel 
supported by European Regional Development Funds RE0022527 ZEBRATOX(EU-Région Réunion-French State national counterpart,to Nicolas Diotel and Jean-Loup Bascands).
After brain damage,regenerative angiogenesis and neurogenesis have been shown to occur simultaneously in mammals,suggesting a close link between these processes.However,the mechanisms by which these processes interact...
关键词：ANGIOGENESIS cerebral damage inflammation NEUROGENESIS stab wound TELENCEPHALON vascular endothelial growth factor ZEBRAFISH 
Neurogenesis dynamics in the olfactory bulb:deciphering circuitry organization, function, and adaptive plasticity
《Neural Regeneration Research》2025年第6期1565-1581,共17页Moawiah M.Naffaa 
Adult neurogenesis persists after birth in the subventricular zone, with new neurons migrating to the granule cell layer and glomerular layers of the olfactory bulb, where they integrate into existing circuitry as inh...
关键词：network adaptability NEUROGENESIS neuronal communication olfactory bulb olfactory learning olfactory memory synaptic plasticity 
The complex roles of m^(6)A modifications in neural stem cell proliferation, differentiation, and self-renewal and implications for memory and neurodegenerative diseases
《Neural Regeneration Research》2025年第6期1582-1598,共17页Yanxi Li Jing Xue Yuejia Ma Ke Ye Xue Zhao Fangliang Ge Feifei Zheng Lulu Liu Xu Gao Dayong Wang Qing Xia 
supported by the Natural Science Foundation of Heilongjiang Province of China,Outstanding Youth Foundation,No.YQ2022H003 (to DW)。
N6-methyladenosine(m^(6)A), the most prevalent and conserved RNA modification in eukaryotic cells, profoundly influences virtually all aspects of mRNA metabolism. mRNA plays crucial roles in neural stem cell genesis a...
关键词：Alzheimer's disease cell self-renewal central nervous system MEMORY MICROGLIA nerve regeneration neurodegenerative diseases NEUROGENESIS RNA methylation 
Potential role of tanycyte-derived neurogenesis in Alzheimer's disease
《Neural Regeneration Research》2025年第6期1599-1612,共14页Guibo Qi Han Tang Jianian Hu Siying Kang Song Qin 
supported by the National Natural Science Foundation of China,Nos.31871477,32170971 (both to SQ);the Qing-Feng Scholar Research Foundation of Shanghai Medical College,Fudan University,No.QF2212 (to HT)。
Tanycytes, specialized ependymal cells located in the hypothalamus, play a crucial role in the generation of new neurons that contribute to the neural circuits responsible for regulating the systemic energy balance. T...
关键词：Alzheimer's disease blood–brain barrier ependymoglial cells HYPOTHALAMUS metabolic diseases neural stem cells NEUROGENESIS neuroinflammatory diseases NEURONS TANYCYTE 
Therapeutic potential of stem cells in subarachnoid hemorrhage
《Neural Regeneration Research》2025年第4期936-945,共10页Hideki Kanamaru Hidenori Suzuki 
funded by Taiju Life Social Welfare Foundation(to HS).
Aneurysm rupture can result in subarachnoid hemorrhage,a condition with potentially severe consequences,such as disability and death.In the acute stage,early brain injury manifests as intracranial pressure elevation,g...
关键词：delayed cerebral ischemia early brain injury matricellular protein NEUROGENESIS stem cell therapy subarachnoid hemorrhage 
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