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TREATMENT: 作品数：7672被引量：19361H指数：38; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：程金伟魏锐利柴立元徐宏彬袁坚更多>>; 相关机构：第二军医大学复旦大学华中科技大学中国人民解放军总医院更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划中国博士后科学基金广东省自然科学基金更多>>

Current understanding and prospects for targeting neurogenesis in the treatment of cognitive impairment: 《Neural Regeneration Research》2026年第1期141-155,共15页Ye Liu Xibing Ding Shushan Jia Xiyao Gu; supported by Technological Innovation 2030-Major Projects of“Brain Science and Brain-like Research,”No.2022ZD0206200(to XG);the National Natural Science Foundation of China,No.82371245(to SJ),82102246(to XD),81701092(to XG);the Natural Science Foundation of Shandong Province,No.ZR2020MH129(to SJ);Shanghai Municipal Key Clinical Specialty,No.shslczdzk03601;Shanghai Engineering Research Center of Peri-operative Organ Support and Function Preservation,No.20DZ2254200。; Adult hippocampal neurogenesis is linked to memory formation in the adult brain,with new neurons in the hippocampus exhibiting greater plasticity during their immature stages compared to mature neurons.Abnormal adult ...; 关键词：aging Alzheimer's disease cerebrovascular diseases cognitive impairment energy metabolism HIPPOCAMPUS immune mechanisms NEUROGENESIS pathological states TREATMENT

Potential treatment of Alzheimer's disease astrocyte pathology based on nuclear lipid regulation: 《Neural Regeneration Research》2026年第1期322-323,共2页Masato Komai Nobumasa Takasugi; supported by a grant from the Japan Foundation for applied enzymology (to NT);the Grant-in-Aid for Scientific Research (C) from the Japan Society for the Promotion of Science (26430059, 17K08272, and 20K07014 to NT);the establishment of university fellowships toward the creation of science technology innovation (JPMJFS2128);a Grant-in-Aid for JSPS Fellows (23KJ1603)(to MK)。; The purpose of this perspective is to discuss the future development of a potential treatment of glial pathology in Alzheimer's disease(AD) and a new regulatory mechanism, nuclear lipids, which may be involved in the ...; 关键词：PATHOLOGY ALZHEIMER

Mitochondrial transplantation:a promising strategy for the treatment of retinal degenerative diseases: 《Neural Regeneration Research》2025年第12期3370-3387,共18页Jing Chi Bin Fan Yulin Li Qing Jiao Guang-Yu Li; supported by the National Natural Science Foundation of China,Nos.8247041526,81570864,82171053(to GYL)。; The retina,a crucial neural tissue,is responsible for transforming light signals into visual information,a process that necessitates a significant amount of energy.Mitochondria,the primary powerhouses of the cell,play...; 关键词：age-related macular degeneration Leber’s hereditary optic neuropathy mitochondrial transfer mitochondrial transplantation retinal degenerative diseases

Optimizing non-invasive vagus nerve stimulation for treatment in stroke: 《Neural Regeneration Research》2025年第12期3388-3399,共12页Sheharyar S.Baig Samantha Dorney Mudasar Aziz Simon M.Bell Ali N.Ali Li Su Jessica N.Redgrave Arshad Majid; an Association of British Neurologists Doctoral Research Fellowship co-funded by the Berkeley Foundation and the Stroke Association;supported by a NIHR Academic Clinical Lectureship in Neurology CL-2020-04-004 NIHR;supported by the NIHR Sheffield Biomedical Research Centre(BRC);NIHR Sheffield Clinical Research Facility(CRF);supported by NIHR EME Project Grant NIHR133169;funded by Alzheimer’s Research UK Senior Research Fellowship(ARUK-SRF2017B-1)。; Stroke remains a leading cause of long-term disability worldwide.There is an unmet need for neuromodulatory therapies that can mitigate against neurovascular injury and potentially promote neurological recovery.Transc...; 关键词：NEUROMODULATION NEUROPLASTICITY REHABILITATION STROKE vagal nerve stimulation vagus nerve stimulation

Targeting capabilities of engineered extracellular vesicles for the treatment of neurological diseases: 《Neural Regeneration Research》2025年第11期3076-3094,共19页Xinyu Yang Xiangyu Gao Xiaofan Jiang Kangyi Yue Peng Luo; supported by the National Natural Science Foundation of China,Nos.82171363,82371381(to PL),82171458(to XJ);Key Research and Development Project of Shaa nxi Province,Nos.2024SF-YBXM-404(to KY)。; Recent advances in research on extracellular vesicles have significantly enhanced their potential as therapeutic agents for neurological diseases.Owing to their therapeutic properties and ability to cross the blood–b...; 关键词：Alzheimer's disease amyotrophic lateral sclerosis engineered extracellular vesicles GLIOMA ischemic stroke neurological diseases Parkinson's disease PSYCHOSIS targeted drug delivery traumatic brain injury

Genistein:a possible solution for the treatment of Alzheimer’s disease: 《Neural Regeneration Research》2025年第10期2903-2905,共3页Karolina Pierzynowska Bartosz Karaszewski Grzegorz Węgrzyn; supported by Fundacja ORLEN(donation No.161/XI/2022)(to GW).; Neurodegenerative diseases are defined as disorders resulting from the slow and progressive loss of function and eventual death of neural cells that result from the primary pathology of nervous tissue.They can lead to...; 关键词：ORGANS ALZHEIMER DEATH

The dopaminergic system and Alzheimer's disease被引量：1: 《Neural Regeneration Research》2025年第9期2495-2512,共18页Yuhan Zhang Yuan Liang Yixue Gu; Alzheimer's disease is a common neurodegenerative disorder in older adults.Despite its prevalence,its pathogenesis remains unclea r.In addition to the most widely accepted causes,which in clude excessive amyloid-beta ...; 关键词：adverse drug reaction Alzheimer's disease CATECHOLAMINE dopamine receptor dopamine receptor heterodimers dopaminergic system neurodegenerative disease NEUROTRANSMITTER signaling pathways traditional Chinese medicine TREATMENT

Protein arginine methyltransferase-6 regulates heterogeneous nuclear ribonucleoprotein-F expression and is a potential target for the treatment of neuropathic pain: 《Neural Regeneration Research》2025年第9期2682-2696,共15页Xiaoyu Zhang Yuqi Liu Fangxia Xu Chengcheng Zhou Kaimei Lu Bin Fang Lijuan Wang Lina Huang Zifeng Xu; supported by the National Natural Science Foundation of China,Nos.82001178(to LW),81901129(to LH),82001175(to FX);Shanghai Sailing Program,No.20YF1439200(to LW);the Natural Science Foundation of Shanghai,China,No.23ZR1450800(to LH);and the Fundamental Research Funds for the Central Universities,No.YG2023LC15(to ZX)。; Protein arginine methyltransferase-6 participates in a range of biological functions,particularly RNA processing,transcription,chromatin remodeling,and endosomal trafficking.However,it remains unclear whether protein ...; 关键词：dorsal root ganglion heterogeneous nuclear ribonucleoprotein F neuropathic pain protein arginine methyltransferase-6 sensory neurons

Treatment of immunoglobulin A nephropathy:Current perspective and future prospects: 《World Journal of Clinical Cases》2025年第19期5-10,共6页Yusuf ZiyaŞener SeherŞener; Immunoglobulin(Ig)A nephropathy is the most common type of primary glomerulonephritis globally.It typically manifests with microscopic hematuria and a spectrum of proteinuria,although rapidly progressive glomeruloneph...; 关键词：Immunoglobulin A nephropathy Telitacicept Complement inhibitors B-cell lineage depletion Anti-proteinuric treatment

Nanoparticles for the treatment of spinal cord injury: 《Neural Regeneration Research》2025年第6期1665-1680,共16页Qiwei Yang Di Lu Jiuping Wu Fuming Liang Huayi Wang Junjie Yang Ganggang Zhang Chen Wang Yanlian Yang Ling Zhu Xinzhi Sun; supported by the Key Research Projects of Universities of Henan Province,No.21A320064 (to XS);the National Key Research and Development Program of China,No.2021YFA1201504 (to LZ);the Strategic Priority Research Program of the Chinese Academy of Science,No.XDB36000000 (to CW);the National Natural Science Foundation of China,Nos.31971295,12374406 (both to LZ)。; Spinal cord injuries lead to significant loss of motor, sensory, and autonomic functions, presenting major challenges in neural regeneration. Achieving effective therapeutic concentrations at injury sites has been a s...; 关键词：ANTIOXIDANTS axon regeneration biocompatible materials drug carriers NANOPARTICLES nerve regeneration neuroinflammatory diseases NEUROPROTECTION spinal cord injury stem cells

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