HIPPOCAMPUS

作品数：712被引量：1995H指数：17
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相关作者：林强徐永健孙彬秦耿彭正午更多>>
相关机构：中国科学院中国科学院大学中山大学青岛大学更多>>
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相关基金：国家自然科学基金国家重点基础研究发展计划中国博士后科学基金广东省自然科学基金更多>>
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Blood-brain barrier disruption and neuroinflammation in the hippocampus of a cardiac arrest porcine model:Single-cell RNA sequencing analysis
《Neural Regeneration Research》2026年第2期742-755,共14页Tangxing Jiang Yaning Li Hehui Liu Yijun Sun Huidan Zhang Qirui Zhang Shuyao Tang Xu Niu Han Du Yinxia Yu Hongwei Yue Yunyun Guo Yuguo Chen Feng Xu 
supported by the National Science Foundation of China,Nos.82325031(to FX),82030059(to YC),82102290(to YG),U23A20485(to YC);Noncommunicable Chronic Diseases-National Science and Technology Major Project,No.2023ZD0505504(to FX),2023ZD0505500(to YC);the Key R&D Program of Shandong Province,No.2022ZLGX03(to YC).
Global brain ischemia and neurological deficit are consequences of cardiac arrest that lead to high mortality.Despite advancements in resuscitation science,our limited understanding of the cellular and molecular mecha...
关键词：Blood-brain barrier disruption cardiac arrest HIPPOCAMPUS microglia NEUROINFLAMMATION neuroprotection NEUTROPHIL oligodendrocyte dysfunction S100A8 single-cell RNA sequencing 
Adiponectin as a potential mediator of the pro-cognitive effects of physical exercise on Alzheimer's disease
《Neural Regeneration Research》2026年第1期96-106,共11页Hui-Hui Guo Hai-Ning Ou Jia-Sui Yu Julia Macedo Rosa Douglas Affonso Formolo Tong Cheng Suk-Yu Yau Hector Wing Hong Tsang 
supported by the National Natural Science Foundation of China,No.82072529(to HWHT);Key Laboratory of Guangdong Higher Education Institutes,No.2021KSYS009(to HWHT);the China Postdoctoral Science Foundation,No.2022M720907(to HHG)。
Alzheimer's disease is the primary cause of dementia and imposes a significant socioeconomic burden globally.Physical exercise,as an effective strategy for improving general health,has been largely reported for its ef...
关键词：adiponectin receptor agonists ADIPONECTIN Alzheimer's disease amyloid-β HIPPOCAMPUS learning and memory physical exercise TAU 
Current understanding and prospects for targeting neurogenesis in the treatment of cognitive impairment
《Neural Regeneration Research》2026年第1期141-155,共15页Ye Liu Xibing Ding Shushan Jia Xiyao Gu 
supported by Technological Innovation 2030-Major Projects of“Brain Science and Brain-like Research,”No.2022ZD0206200(to XG);the National Natural Science Foundation of China,No.82371245(to SJ),82102246(to XD),81701092(to XG);the Natural Science Foundation of Shandong Province,No.ZR2020MH129(to SJ);Shanghai Municipal Key Clinical Specialty,No.shslczdzk03601;Shanghai Engineering Research Center of Peri-operative Organ Support and Function Preservation,No.20DZ2254200。
Adult hippocampal neurogenesis is linked to memory formation in the adult brain,with new neurons in the hippocampus exhibiting greater plasticity during their immature stages compared to mature neurons.Abnormal adult ...
关键词：aging Alzheimer's disease cerebrovascular diseases cognitive impairment energy metabolism HIPPOCAMPUS immune mechanisms NEUROGENESIS pathological states TREATMENT 
Persistent alterations in gray matter in COVID-19 patients experiencing sleep disturbances:a 3-month longitudinal study
《Neural Regeneration Research》2025年第10期3013-3024,共12页Kaixuan Zhou Gaoxiong Duan Ying Liu Bei Peng Xiaoyan Zhou Lixia Qin Lingyan Liang Yichen Wei Qingping Zhang Xiaocheng Li Haixia Qin Yinqi Lai Yian Lu Yan Zhang Jiazhu Huang Jinli Huang Yinfei Ouyang Bolin Bin Mingming Zhao Jun Liu Jianrong Yang Demao Deng 
supported by grants from Major Project of Science and Technology of Guangxi Zhuang Autonomous Region,No.Guike-AA22096018(to JY);Guangxi Key Research and Development Program,No.AB22080053(to DD);Major Project of Science and Technology of Guangxi Zhuang Autonomous Region,No.Guike-AA23023004(to MZ);the National Natural Science Foundation of China,Nos.82260021(to MZ),82060315(to DD);the Natural Science Foundation of Guangxi Zhuang Autonomous Region,No.2021GXNSFBA220007(to GD);Clinical Research Center For Medical Imaging in Hunan Province,No.2020SK4001(to JL);Key Emergency Project of Pneumonia Epidemic of Novel Coronavirus Infection in Hunan Province,No.2020SK3006(to JL);Science and Technology Innovation Program of Hunan Province,No.2021RC4016(to JL);Key Project of the Natural Science Foundation of Hunan Province,No.2024JJ3041(to JL).
Sleep disturbances are among the most prevalent neuropsychiatric symptoms in individuals who have recovered from severe acute respiratory syndrome coronavirus 2 infections.Previous studies have demonstrated abnormal b...
关键词：brain structure cortical gray matter volume cortical surface area cortical thickness HIPPOCAMPUS magnetic resonance imaging Pittsburgh Sleep Quality Index severe acute respiratory syndrome coronavirus 2 infections sleep disturbances sub-cortical volume 
How dopamine tunes parvalbumin interneurons in the hippocampus:new experimental observations in Alzheimer's disease
《Neural Regeneration Research》2025年第5期1405-1406,共2页Livia La Barbera Paraskevi Krashia Annalisa Nobili 
supported by an under-40 grant from the Italian Association for Alzheimer’s Research [AIRALZH AGYR2021];the Strategic University Projects–Young Researcher Independence grant [YRG2021] from the Università Campus Bio-Medico di Roma (Rome, Italy)(to LLB);Italian Ministry of Health [Research Grant:GR-2019-12370446];the American Alzheimer’s Association [AARG-22-922961](to PK)。
Despite decades of dedicated resea rch,Alzheimer's disease (AD) is an age-related and progressive neurodegenerative disorder for which the mechanisms of onset are sti unc ear.AD is cha racterized by featured histologi...
关键词：ALZHEIMER alterations DOPAMINE 
Exercise preconditioning alleviates ischemia-induced memory deficits by increasing circulating adiponectin
《Neural Regeneration Research》2025年第5期1445-1454,共10页Meifeng Zheng Borui Zhang Sonata S Y Yau Kwok-Fai So Li Zhang Haining Ou 
supported by STI2030-Major Projects,No.2022ZD0207600(to LZ);the National Natural Science Foundation of China,Nos.32070955(to LZ),U22A20301(to KFS);the Natural Science Foundation of Guangdong Province,No.2021A1515012197(to HO);Guangzhou Core Medical Disciplines Project,No.2021-2023(to HO);Key Research and Development Plan of Ningxia Hui Automomous Region,No.2022BEG01004(to KFS);Science and Technology Program of Guangzhou,China,No.202007030012(to KFS and LZ)。
Cerebral ischemia is a major health risk that requires preventive approaches in addition to drug therapy.Physical exercise enhances neurogenesis and synaptogenesis,and has been widely used for functional rehabilitatio...
关键词：ADIPONECTIN cerebral ischemia exercise pre-conditioning HIPPOCAMPUS memory function middle cerebral artery occlusion prefrontal cortex synaptic proteins treadmill exercise 
The toxic impacts of microplastics-borne benzo[a]pyrene and heavy metals on the health and behavior of seahorse Hippocampus erectus
《Journal of Oceanology and Limnology》2025年第2期559-571,共13页Ying LIU Nan LI Dongwei SHANG Yanjing YANG Pei CUI Jinhui SUN 
Supported by the Marine Economic Development Project(No.GDNRC[2022]36);the National Key Research and Development Program of China(No.2018YFD0900206);the Tianjin Science and Technology Program Project(No.21YDTPJC00340)。
Marine pollution poses a critical threat to biodiversity.The synergistic effects of microplastics,specifically high-density polyethylene(HDPE),combined with benzo[a]pyrene(B[a]P)and heavy metals,on the physiology and ...
关键词：microplastics(MP) heavy metal benzo[a]pyrene(B[a]P) SEAHORSE synergistic effect 
Alternations in morphometric similarity network in mesial temporal epilepsy correlate to neuroinflammatory pathway gene transcriptions
《Acta Epileptologica》2025年第1期94-104,共11页Lu Lu Chenyang Zhao Weihao Liao Peiyu Wang Yingying Zhang Dongmei An Xintong Wu Hesheng Zhang Ping Jiang Yaohui He Jinpeng Niu Wei Li Kangjia Chen Su Lui Yu Zhao Qiyong Gong Bo Wang Wei Liao Josemir W.Sander Lin Chen Dong Zhou 
supported by the National Natural Science Foundation of China(U21A20393);the 1.3.5 project for disciplines of excellence and the Brain Science project of West China Hospital(ZYGD23032);the postdoctoral research fund of West China Hospital(2024HXBH095);the National Key R&D Program(2021YFC2401204,2022YFC2503805);the NIHR University College London Hospitals Biomedical Research Centre;the UK Department of Health sponsors;support from the Marvin Weil Epilepsy Research Fund;the UK Epilepsy Society;the National Institute of Health Research;the Academy of Medical Sciences.
Background Mesial temporal lobe epilepsy(mTLE)is the most common form of focal epilepsy,often associated with hippocampal sclerosis.Increasing evidence suggests the pivotal role of neuroinflammation in mTLE onset and ...
关键词：Allen Human Brain Atlas Imaging transcriptome analysis Hippocampus sclerosis 
不同饵料特性对水层转化期海马摄食行为的影响研究
《水产研究》2025年第1期20-28,共9页杨熠珊 潘聪 任朝宇 李安然 杨岚心 孙金辉 张永明 
为提高海马(5.67 ± 0.12 cm)幼苗在水层转化期的成活率和明确水层转化期幼海马最适规格饵料,本研究运用行为学手段,通过控制不同的饵料特性,揭示海马的摄食行为和偏好选择,为提高海马成活率和饵料开发提供科学数据。本研究共设置不同...
关键词：大海马(Hippocampus kuda Bleeker) 摄食行为 饵料特性 摄食参数 
Artemisinin inhibits neuronal ferroptosis in Alzheimer’s disease models by targeting KEAP1
《Acta Pharmacologica Sinica》2025年第2期326-337,共12页Peng-xi Deng Marta Silva Na Yang Qing Wang Xin Meng Ke-qiang Ye Hong-chang Gao Wen-hua Zheng 
supported by National Natural Science Foundation of China(32070969 and 22274115);the Science and Technology Development Fund,Macao SAR(0104/2022/A2 and 0038/2020/AMJ);Guangdong,Hong Kong and Macao Joint Key Laboratory for New Drug Screening(EF2023-00054-FHS,GDSTC);the Guangdong Provincial Funding Committee for Basic and Applied Fundamental Research(2022-Natural Science Foundation,EF019/FHS-ZWH/2022,GDSTC);University of Macao(MYRG-CRG2024-00019-FHS,MYRG-GRG2023-00118-FHS-UMDF and MYRG2022-00154-FHS).
Ferroptosis,a form of cell death characterized by lipid peroxidation,is involved in neurodegenerative diseases such as Alzheimer´s disease(AD).Recent studies have shown that a first-line antimalarial drug artemisinin...
关键词：Alzheimer’s disease ARTEMISININ ferroptosis KEAP1 Nrf2 HIPPOCAMPUS 
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