DOPAMINE

作品数:528被引量:879H指数:11
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相关领域:医药卫生更多>>
相关作者:王俊姜宏谢俊霞邱海波杨毅更多>>
相关机构:首都医科大学北京大学中国科学院山东大学更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划中国博士后科学基金北京市自然科学基金更多>>
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Adeno-associated viral vectors for modeling Parkinson's disease in non-human primates
《Neural Regeneration Research》2026年第1期224-232,共9页Julia Chocarro JoséL.Lanciego 
supported by grants PID2020-120308RB-I00 and PID2023-147802OB-I00 funded by MICIU/AEI/10.13039/501100011033;FEDER,UE,by Aligning Science Across Parkinson’s(ref.ASAP-020505)through the Michael J.Fox Foundation for Parkinson’s Research;by CiberNed Intramural Collaborative Projects(ref.PI2020/09);by the Spanish Fundación Mutua Madrile?a de Investigación Médica(to JLL)。
The development of clinical candidates that modify the natural progression of sporadic Parkinson's disease and related synucleinopathies is a praiseworthy endeavor,but extremely challenging.Therapeutic candidates that...
关键词:adeno-associated viral vectors ALPHA-SYNUCLEIN DOPAMINE Lewy bodies NEURODEGENERATION NEUROMELANIN NEUROPATHOLOGY substantia nigra 
Context-dependency in medicine:how neuronal excitability influences the impact of dopamine on cognition
《Neural Regeneration Research》2025年第11期3225-3226,共2页Mahboubeh Ahmadi Nahid Rouhi Javad Mirnajafi-Zadeh Bechara J.Saab 
Dopamine,often termed the"feel-good"neurotransmitter,plays a crucial role in myriad physiological and psychological brain processes.While dopamine is primarily associated with pleasure,reward,and motivation,its effect...
关键词:DOPAMINE EPILEPSY primarily 
All Optic-Fiber Waveguide-Coupled SPR Sensor for CRP Sensing Based on Dielectric Layer and Poly-Dopamine
《Photonic Sensors》2025年第2期98-109,共12页Jinying MA Shixin LI Xiangdong HUANG Junfeng JIANG Tianhua XU Tiegen LIU 
funded by the National Key Research and Development Program of China(Grant No.2022YFF0706003);National Natural Science Foundation of China(Grant No.62375202).
We developed an all optic-fiber waveguide-coupled surface plasmon resonance(SPR)sensor using zirconium disulfide(ZrS_(2))and poly-dopamine(PDA)as the dielectric layer and biological cross-linker,respectively.This sens...
关键词:Surface plasmon resonance(SPR) dielectric layer poly-dopamine(PDA) C-reactive protein(CRP) 
Challenges in using virtual reality technology for pain relief
《World Journal of Clinical Cases》2025年第16期76-79,共4页Takahiko Nagamine 
The present paper addresses two issues pertaining to the use of virtual reality(VR).One issue pertains to the equipment utilized.VR technology can be classified into two main categories:Immersive and non-immersive.The...
关键词:Virtual reality Acute pain Chronic pain Brain network:Medial prefrontal cortex DOPAMINE 
How dopamine tunes parvalbumin interneurons in the hippocampus:new experimental observations in Alzheimer's disease
《Neural Regeneration Research》2025年第5期1405-1406,共2页Livia La Barbera Paraskevi Krashia Annalisa Nobili 
supported by an under-40 grant from the Italian Association for Alzheimer’s Research [AIRALZH AGYR2021];the Strategic University Projects–Young Researcher Independence grant [YRG2021] from the Università Campus Bio-Medico di Roma (Rome, Italy)(to LLB);Italian Ministry of Health [Research Grant:GR-2019-12370446];the American Alzheimer’s Association [AARG-22-922961](to PK)。
Despite decades of dedicated resea rch,Alzheimer's disease (AD) is an age-related and progressive neurodegenerative disorder for which the mechanisms of onset are sti unc ear.AD is cha racterized by featured histologi...
关键词:ALZHEIMER alterations DOPAMINE 
Progressive noradrenergic degeneration and motor cortical dysfunction in Parkinson’s disease
《Acta Pharmacologica Sinica》2025年第4期829-835,共7页Wei Zhou Hong-Yuan Chu 
funded in part by Aligning Science Across Parkinson’s(ASAP-020572);NIH grants(R01NS121371 and R21NS135545);Department of Defense Congressionally Directed Medical Research Programs(W81XWH-21-1-0943);Parkinson’s Foundation(PF-IMP-1045313).
The locus coeruleus norepinephrine(LC-NE)system plays an important role in regulating brain function,and its neuronal loss has been well-documented in Parkinson’s disease(PD).The LC-NE neurodegeneration is believed t...
关键词:locus coeruleus NOREPINEPHRINE DOPAMINE parkinson’s disease motor cortex cognition 
Electropolymerized Dopamine Film-Modified Optical Fiber LMR Biosensor for Immunoassay
《Photonic Sensors》2025年第1期138-152,共15页Xiaoshuang DAI Shuang WANG Yongle LI Junfeng JIANG Ke TAN Hongyu LIU Zhiyuan LI Tianhua XU Tiegen LIU 
supported in parts by National Key Scientific Instrument and Equipment Development Projects of China(Grant No.2022YFF0706000);National Natural Science Foundation of China(Grant No.62035006);Independent Innovation Found of Tianjin University,China(Grant No.2023XCG-0028);Tianjin Research Innovation Project for Postgraduate Students,China(Grant No.2022BKY064).
In producing high-performance optical biosensors,the selected coupling agent and its fixation mode play an essential role as one of the decisive conditions for antibody incubation.In this work,we designed optical fibe...
关键词:Optical fiber biosensor lossy mode resonance ITO electropolymerized dopamine surface functionalization 
Restless head syndrome:A retrospective study
《World Journal of Methodology》2025年第1期51-59,共9页Sanjay Prakash Varoon Vadodaria Niraj Chawda Chetsi S Shah Anurag Prakash 
BACKGROUND Restless legs syndrome(RLS)is characterized by an urge to move with an unpleasant sensation in the lower limbs.RLS typically affects the legs.However,it can also affect several other body regions,such as th...
关键词:Restless legs syndrome Restless head syndrome DOPAMINE HEADACHE MIGRAINE Tension-type headache 
Study on Dopamine Electrochemical Sensing Based on Au@MoS_(2)
《电化学(中英文)》2025年第3期35-46,共12页Ning An Ni Su Xin-Ran Li Jian-Yu Liu Qi-Yan Wang 
supported by the Young Talent Innovation Team Support Project from Zhengzhou University(No.32213280);the scientific research program of innovation platform in State Tobacco Monopoly Administration;the State Key Program of National Natural Science Foundation of China(Grant No.32130083).
Dopamine(DA)is a vital neurotransmitter,and accurate detection of its concentration is critical for both clinical diagnos-tics and neuroscience research.Due to its electrochemical activity,DA is commonly detected usin...
关键词:DOPAMINE Electrochemical sensor Molybdenum disulfide Gold nanoparticles 
Activation of D2-like dopamine receptors improves the neuronal network and cognitive function of PPT1KI mice
《Acta Pharmacologica Sinica》2025年第2期338-352,共15页Jun-qiang Zhao Bing-yan Feng Zhen-li Ye Xiao-yin Ma Jing-zhi Du Jun-mei Li Wan-liu Wu Jing-jing Gao Song-ji Li Shi-yong Peng Ji-sen Huai Li-hao Ge Cheng-biao Lu 
supported by the National Natural Science Foundation of China(NSFC:81771517,81271422);the Key Project of the 14th Five-Year Plan of Educational Science in Henan Province(2021JKZD09);the Key Scientific and Technological Project in Henan Province(212102310654);the Henan Province Medical Science and Technology Key Project Jointly Constructed by Province and Ministry(SBGJ202102189);the Key R&D and Promotion Projects in Henan Province(222102310615);Natural Science Foundation of Henan Province(242300421307);the Tai-hang Scholar Research Fund from Xinxiang Medical University;and the Henan Collaborative Innovation Center of Prevention and Treatment of Mental Disorders,the Second Affiliated Hospital of Xinxiang Medical University(XTkf11).
Palmitoyl-protein thioesterase 1(PPT1)is a lysosomal depalmitoylation enzyme that mediates protein posttranslational modifications.Loss-of-function mutation of PPT1 causes a failure of the lysosomal degradation of pal...
关键词:infantile neuronal ceroid lipofuscinosis palmitoyl-protein thioesterase 1 cognitive functions γoscillations DOPAMINE dopamine D4 receptor 
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