BACKGROUND The etiological diagnosis of intracranial hypertension is quite complicated but important in clinical practice.Some common causes are craniocerebral injury,intracranial space-occupying lesion,subarachnoid h...
supported by the National Key R&D Program of China (2016YFC1306700);the National Natural Science Foundation of China (91332102 and 31271130)
The locus coeruleus(LC) has been studied in major depressive disorder(MDD) and bipolar disorder(BD). A major problem of immunocytochemical studies in the human LC is interference with the staining of the immunocytoche...
Progressive Recent Memory loss is the main complaint in Alzheimer’s disease patients. There is not a simple or congruous explanation yet due to highly complex mechanisms by which the Central Nervous System store and ...
The loss of pigmented neurons from the human brain has long been the hallmark of Parkinson's disease(PD).Neuromelanin(NM) in the pre-synaptic terminal of dopamine neurons is emerging as a primary player in the et...
Idiopathic Parkinson's disease (IPD) is a progressive, neurodegenerative movement disorder characterized by bradykinesia, muscular rigidity, pos- tural instability and tremor. IPD is usually diagnosed based on clin...
the National Natural Science Foundation of China, No. 30600201;the Tianjin Science and Technology Committee, No. 07JCYBJC09900
To investigate the effects of oxidative stress on substantia nigra neuronal degeneration and death in patients with Parkinson's disease, we treated neuroblastoma cells (SK-N-SH) and glioma cells with Fenton's reag...