Intracranial hypertension as the primary symptom of malignant melanoma:A case report  

作　　者：Hai-Ting Xie Ding-Hao An Duo-Bin Wu 

机构地区：[1]Department of Neurology,Southern Medical University,Guangzhou 510282,Guangdong Province,China [2]Department of Neurology,Nanjing Drum Tower Hospital,Chinese Academy of Medical Sciences&Peking Union Medical College,Nanjing 210008,Jiangsu Province,China [3]Department of Neurology,Zhujiang Hospital of Southern Medical University,Guangzhou 510282,Guangdong Province,China

出　　处：《World Journal of Clinical Cases》2024年第21期4836-4841,共6页世界临床病例杂志

摘　　要：BACKGROUND The etiological diagnosis of intracranial hypertension is quite complicated but important in clinical practice.Some common causes are craniocerebral injury,intracranial space-occupying lesion,subarachnoid hemorrhage,and hydrocephalus.When a patient presents with intracranial hypertension,the common causes are to be considered first so that other causes would be dismissed.With the morbidity lower than 9%,neuromelanin is very rare.Common symp-toms include nerve damage symptoms,epilepsy,psychiatric symptoms,and cognitive disorders.CASE SUMMARY We present a patient with melanoma which manifested with isolated intracranial hypertension without any other neurological signs.A 22-year-old male had repeated nausea and vomiting for 2 mo with Babinski sign(+)on both sides,nuchal rigidity,and subarachnoid hemorrhage.He had been diagnosed with melanoma and was given surgery and whole-brain radiation.Ultimately,the patient died 2 mo later.CONCLUSION Malignant melanoma should be taken into consideration in the differential diagnosis of intracranial hypertension.

关 键 词：Intracranial hypertension DIAGNOSIS MELANOMA NEUROMELANIN Case report 

分 类 号：R739.41[医药卫生—肿瘤]