医药卫生—肿瘤

作品数:1410721被引量:1538244H指数:220
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相关作者:吴孟超李建勇刘宝瑞单保恩汤钊猷更多>>
相关机构:复旦大学华中科技大学中国医科大学第二军医大学更多>>
发文主题:乳腺癌肿瘤预后胃癌肺癌更多>>
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发文基金:国家自然科学基金广东省自然科学基金国家重点基础研究发展计划广东省科技计划工业攻关项目更多>>
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Enhanced neurogenesis after ischemic stroke:The interplay between endogenous and exogenous stem cells
《Neural Regeneration Research》2026年第1期212-223,共12页Ruxu Geng Yuhe Wang Renzhi Wang Jun Wu Xinjie Bao 
supported by the National Key Research and Development Program of China,No.2018YFA0108602;the CAMS Initiative for Innovative Medicine,No.2021-1-I2M-019;National High-Level Hospital Clinical Research Funding,No.2022-PUMCH-C-042(all to XB)。
Ischemic stroke is a significant global health crisis,frequently resulting in disability or death,with limited therapeutic interventions available.Although various intrinsic reparative processes are initiated within t...
关键词:brain-derived neurotrophic factor endogenous neuroregeneration exosomes hydrogels ischemic stroke mesenchymal stem cells neural stem cells NEUROGENESIS stem cell transplantation 
Changes in border-associated macrophages after stroke: Single-cell sequencing analysis
《Neural Regeneration Research》2026年第1期346-356,共11页Ning Yu Yang Zhao Peng Wang Fuqiang Zhang Cuili Wen Shilei Wang 
supported by Qingdao Key Medical and Health Discipline Project;The Intramural Research Program of the Affiliated Hospital of Qingdao University,No. 4910;Qingdao West Coast New Area Science and Technology Project,No. 2020-55 (all to SW)。
Border-associated macrophages are located at the interface between the brain and the periphery, including the perivascular spaces, choroid plexus, and meninges. Until recently, the functions of border-associated macro...
关键词:border-associated macrophages CLODRONATE hypoxia ISCHEMIA-REPERFUSION ischemic stroke liposomes neuroinflammation single-cell sequencing analysis STAT3 tumor necrosis factor 
Empowering the NSC-34 cell line as a motor neuron model: Cytosine arabinoside's action
《Neural Regeneration Research》2026年第1期357-364,共8页Giuseppe Vitale Susanna Amadio Francesco Liguori Cinzia Volonté 
supported by FATALSDrug Project [Progetti di Ricerca@CNR SAC.AD002.173.058] from National Research Council,Italy (to CV)。
The NSC-34 cell line is a widely recognized motor neuron model and various neuronal differentiation protocols have been exploited. Under previously reported experimental conditions, only part of the cells resemble dif...
关键词:cytosine arabinoside Islet2 Hb9 Ki67 mitosis inhibition neurite initiation neurite regeneration neuronal differentiation protocol NSC-34 P75 
Microglia overexpressing brain-derived neurotrophic factor promote vascular repair and functional recovery in mice after spinal cord injury
《Neural Regeneration Research》2026年第1期365-376,共12页Fanzhuo Zeng Yuxin Li Xiaoyu Li Xinyang Gu Yue Cao Shuai Cheng He Tian Rongcheng Mei Xifan Mei 
supported by the National Natural Science Foundation of China,Nos.82072165 and 82272256(both to XM);the Key Project of Xiangyang Central Hospital,No.2023YZ03(to RM)。
Spinal cord injury represents a severe form of central nervous system trauma for which effective treatments remain limited.Microglia is the resident immune cells of the central nervous system,play a critical role in s...
关键词:ANGIOGENESIS apoptosis brain-derived neurotrophic factor colony stimulating factor 1 receptor inflammation MICROGLIA motor function spinal cord injury vascular endothelial growth factor 
Long noncoding RNA GAS5 acts as a competitive endogenous RNA to regulate GSK-3β and PTEN expression by sponging miR-23b-3p in Alzheimer's disease
《Neural Regeneration Research》2026年第1期392-405,共14页Li Zeng Kaiyue Zhao Jianghong Liu Mimin Liu Zhongdi Cai Ting Sun Zhuorong Li Rui Liu 
supported by the National Natural Science Foundation of China,Nos. 82173806 and U1803281;Chinese Academy of Medical Sciences (CAMS) Innovation Fund for Medical Science,Nos. 2021-I2M-1-030 and 2022-I2M-2-002;Non-Profit Central Research Institute Fund of Chinese Academy of Medical Sciences,No. 2022-JKCS-08 (all to RL)。
Long noncoding RNA and microRNA are regulatory noncoding RNAs that are implicated in Alzheimer's disease, but the role of long noncoding RNA-associated competitive endogenous RNA has not been fully elucidated. The lon...
关键词:Alzheimer's disease amyloid-beta peptide accumulation cognitive dysfunction competitive endogenous RNA glycogen synthase kinase 3beta lncRNA growth arrest-specific 5 microRNA-23b-3p neuronal apoptosis phosphatase and tensin homologue deleted on chromosome 10 tau phosphorylation 
Current understanding and prospects for targeting neurogenesis in the treatment of cognitive impairment
《Neural Regeneration Research》2026年第1期141-155,共15页Ye Liu Xibing Ding Shushan Jia Xiyao Gu 
supported by Technological Innovation 2030-Major Projects of“Brain Science and Brain-like Research,”No.2022ZD0206200(to XG);the National Natural Science Foundation of China,No.82371245(to SJ),82102246(to XD),81701092(to XG);the Natural Science Foundation of Shandong Province,No.ZR2020MH129(to SJ);Shanghai Municipal Key Clinical Specialty,No.shslczdzk03601;Shanghai Engineering Research Center of Peri-operative Organ Support and Function Preservation,No.20DZ2254200。
Adult hippocampal neurogenesis is linked to memory formation in the adult brain,with new neurons in the hippocampus exhibiting greater plasticity during their immature stages compared to mature neurons.Abnormal adult ...
关键词:aging Alzheimer's disease cerebrovascular diseases cognitive impairment energy metabolism HIPPOCAMPUS immune mechanisms NEUROGENESIS pathological states TREATMENT 
Exosomes in stroke management:A promising paradigm shift in stroke therapy
《Neural Regeneration Research》2026年第1期6-22,共17页Bo Wang Pinzhen Chen Wenyan Li Zhi Chen 
supported by the Natural Science Foundation of Chongqing,No.CSTB2023NSCQ-mSX0561(to WL).
Effective treatment methods for stroke,a common cerebrovascular disease with a high mortality rate,are still being sought.Exosome therapy,a form of acellular therapy,has demonstrated promising efficacy in various dise...
关键词:angiogenesis animal model cerebrovascular disorder extracellular vesicle mortality rates neural stem cell NEUROINFLAMMATION oxidative stress programmed cell death therapy 
Interleukin 10 supplement to reduce episodes of recurrent aphthous stomatitis
《World Journal of Methodology》2025年第3期13-16,共4页Cinzia Casu Angelo Michele Inchingolo Germano Orrù 
Recurrent aphthous stomatitis(RAS)is a very frequent condition in developed countries whose basic symptom is a lesion referred to as an aphthous ulcer.High levels of interleukin(IL)-1 and IL-6 and low salivary levels ...
关键词:Recurrent aphthous stomatitis Interleukin 10 Low-dose medicine Aphthosis INTERLEUKIN 
Clinical inertia in sexual medicine practice
《World Journal of Methodology》2025年第3期25-31,共7页Arkiath Veettil Raveendran 
Clinical inertia(CI)is common in clinical practice.Sexual health issues are common in society,and CI is ubiquitous in sexual medicine practice.CI influences all aspects of healthcare,including prevention,diagnosis,and...
关键词:Clinical inertia Sexual medicine Sexual dysfunction Erectile dysfunction VAGINISMUS 
Echo contrast medium:How the use of contrast echocardiography(ultrasound contrast agents)can improve patient care
《World Journal of Methodology》2025年第3期32-37,共6页Kevan English 
Conventional echocardiography can sometimes pose a challenge to diagnosis due to sub-optimal images.Ultrasound contrast agents(UCAs)have been shown to drastically enhance imaging quality,particularly depicting the lef...
关键词:Ultrasound contrast agents ECHOCARDIOGRAPHY Myocardial perfusion ULTRASOUND Left ventricle OPTISON DEFINITY SONAZOID Lumason 
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