supported by Qingdao Key Medical and Health Discipline Project;The Intramural Research Program of the Affiliated Hospital of Qingdao University,No. 4910;Qingdao West Coast New Area Science and Technology Project,No. 2020-55 (all to SW)。
Border-associated macrophages are located at the interface between the brain and the periphery, including the perivascular spaces, choroid plexus, and meninges. Until recently, the functions of border-associated macro...
This work was supported by DePaul University grant URC450622(to EC).
In the central nervous system,immunologic surveillance and response are carried out,in large part,by microglia.These resident macrophages derive from myeloid precursors in the embryonic yolk sac,migrating to the brain...
This work was supported by the American Association for the Study of Liver Diseases Foundation,Alexandria,VA,USA(2018 Pinnacle Research Award);by the United States National Institutes of Health(grant numbers T32 GM106999,UL1 TR003107,R42 DK079387 and KL2 TR003108).
Background and aim:Acetaminophen(APAP)overdose is a major cause of acute liver injury,but the role of macrophages in the propagation of the hepatotoxicity is controversial.Early research revealed that macrophage inhib...
supported by grants-in-aid for Scientific Research C(16K09852)and B(17H04210)from the Japan Society for the Promotion of Science;research grants from the Shinnihon Foundation of Advanced Medical Treatment Research,SENSHIN Medical Research Foundation;a grant-in-aid for Clinical Research from Miyazaki University Hospital
Background:Monocyte-derived fibrocytes play an important role in the progression of fibrosis in the skin,lungs,heart and kidney.However,the contribution of fibrocytes to liver fibrosis is unclear.The aim of this study...
NINDS R01NS09923(MBB);R01NS081040(JKL);The Miami Project to Cure Paralysis;the Buoniconti Fund
Schwann cell transplantation is a promising therapy for the treatment of spinal cord injury(SCI) and is currently in clinical trials.In our continuing efforts to improve Schwann cell transplantation strategies,we so...
Supported by Jiangsu Planned Projects for Postdoctoral Research Funds,No.1302096B;Natural Science Foundation of Jiangsu Province,No.BK2011484 and No.2012704;National Natural Science Foundation of China,No.81070287
AIM:To investigate the protective effect of clodronatecontaining liposomes against severe acute pancreatitis(SAP)-triggered acute gastric mucosal injury(AGMI) in rats.METHODS:Clodronate- and phosphate-buffered saline(...
Project supported by the National Natural Science Foundation of China(No.81070287);the Natural Science Foundation of Jiangsu Province(Nos.BK2011484 and 2012704),China
Background and objective: It has been shown that macrophages play an important role in the development of severe acute pancreatitis (SAP), and eventually lead to multiple organ failure (MOF). Clodronate-liposome ...
supported by the National Basic Research Program of China(973Program,2011CB910404 and 2012CB966800);China National Natural Science Foundation(30901432 and 30972949);the Chinese Ministry of Education(109056);Program for New Century Excellent Talents in University Award(NCET-08-0131);Shanghai Science and Tech-nology Committee(11DZ2211000).
Metastasis is a very complicated multi-step process and accounts for the low survival rate of the cancerous patients.To metastasize,t he malignant cells must detach from the primary tumor and migrate to secondary site...
supported by grants from the National Natural Science Foundation of China (81070287 and 30772117);the Graduate Research and Innovation Program of Jiangsu University (CX10B_010X)
BACKGROUND: Severe acute pancreatitis (SAP) can result in intestinal mucosal injury. This study aimed to demonstrate the protective effect of clodronate-containing liposomes on intestinal mucosal injury in rats with S...
Project supported by the National Natural Science Foundation of China(No.30772117);the Science Foundation of Jiangsu Province of China(No.BK2007096)
Objectives: Severe acute pancreatitis (SAP) can lead to acute lung injury (ALl). The purpose of this paper is to investigate the protective effect of clodronate-containing liposomes on ALl in rats with SAP. Meth...