MACROPHAGES

作品数：771被引量：2967H指数：23
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相关领域：医药卫生更多>>
相关作者：贾艳慧杜美蓉游育红林志彬张睿卓更多>>
相关机构：复旦大学第二军医大学第四军医大学西京医院南昌大学第一附属医院更多>>
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相关基金：国家自然科学基金国家重点基础研究发展计划中国博士后科学基金广东省自然科学基金更多>>
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Polysialic acid-Siglec immune checkpoints of microglia and macrophages:Perspectives for therapeutic intervention
《Neural Regeneration Research》2026年第2期661-662,共2页Hauke Thiesler Herbert Hildebrandt 
Deutsche Forschungsgemeinschaft(DFG,German Research Foundation),project numbers 324633948 and 409784463(DFG grants Hi 678/9-3 and Hi 678/10-2,FOR2953)to HH;Bundesministerium für Bildung und Forschung-BMBF,project number 16LW0463K to HT.
Microglia are the resident macrophages of the central nervous system.They act as the first line of defense against pathogens and play essential roles in neuroinflammation and tissue repair after brain insult or in neu...
关键词：therapeutic intervention central nervous system immune checkpoints neurodegenerative demyelinating diseases borst MACROPHAGES polysialic acid SIGLEC MICROGLIA 
Microglia and macrophages in brain injury and repair after subarachnoid hemorrhage
《Neural Regeneration Research》2026年第1期308-309,共2页David C.Lauzier Harry V.Vinters Shino D.Magaki 
Subarachnoid hemorrhage(SAH) is a devastating condition that affects a total of 8 million people worldwide each year(Lauzier and Athiraman, 2024). Etiologies of SAH can be traumatic or nontraumatic, with the majority ...
关键词：TRAUMATIC HEMORRHAGE 
Changes in border-associated macrophages after stroke: Single-cell sequencing analysis
《Neural Regeneration Research》2026年第1期346-356,共11页Ning Yu Yang Zhao Peng Wang Fuqiang Zhang Cuili Wen Shilei Wang 
supported by Qingdao Key Medical and Health Discipline Project;The Intramural Research Program of the Affiliated Hospital of Qingdao University,No. 4910;Qingdao West Coast New Area Science and Technology Project,No. 2020-55 (all to SW)。
Border-associated macrophages are located at the interface between the brain and the periphery, including the perivascular spaces, choroid plexus, and meninges. Until recently, the functions of border-associated macro...
关键词：border-associated macrophages CLODRONATE hypoxia ISCHEMIA-REPERFUSION ischemic stroke liposomes neuroinflammation single-cell sequencing analysis STAT3 tumor necrosis factor 
Secretome of polarized macrophages:potential for targeting inflammatory dynamics in spinal cord injury
《Neural Regeneration Research》2025年第11期3231-3232,共2页Andreia Monteiro Susana Monteiro Nuno A.Silva 
funded by national funds,through the Foundation for Science and Technology(FCT)-project UIDB/50026/2020,UIDP/50026/2020(to NAS),EXPL/MEDPAT/0931/2021(to SM);Financial support was provided by Prémios Santa Casa Neurociências-Prize Melo e Castro for Spinal Cord Injury Research(MC-18-2021);Wings For Life Spinal Cord Research Foundation(WFL-PT-14/23);"la Caixa"Foundation(HR23-00484)(to NAS);the FCT for the Scientific Employment Stimulus to NAS and SM(CEECIND/04794/2017 and CEECIND/01902/2017)。
Spinal cord injury(SCI)involves an initial traumatic phase,followed by secondary events such as ischemia,increased blood-spinal cord barrier permeability,ionic disruption,glutamate excitotoxicity,and metabolic alterat...
关键词：alterations injury COMPANIES 
Cardiomyocyte proliferation:Advances and insights in macrophage-targeted therapy for myocardial injury
《Genes & Diseases》2025年第3期108-121,共14页Tao Wang Xueyao Wang Weibin Ren Zeyu Sun Yanhui Zhang Nanping Wu Hongyan Diao 
supported by the National Key Research and Development Program of China(No.2021YFA1301100,2021YFA1301101);Shandong Provincial Natural Science Foundation of China(No.SYS202202);the Research Project of Jinan Microecological Biomedicine Shandong Laboratory(China)(No.JNL-2023009Q,JNL-2022012B).
In the mammalian heart,cardiomyocytes undergo a transient window of proliferation that leads to regenerative impairment,limiting cardiomyocyte proliferation and myocardial repair capacity.Cardiac developmental pattern...
关键词：Cardiac regeneration Cardiomyocyte proliferation Heterogeneous macrophages MACROPHAGES Myocardial infarction 
SPP1þmacrophages in colorectal cancer:Markers of malignancy and promising therapeutic targets
《Genes & Diseases》2025年第3期428-446,共19页Zhenyu Xie Gaozan Zheng Liaoran Niu Kunli Du Ruikai Li Hanjun Dan Lili Duan Hongze Wu Guangming Ren Xinyu Dou Songchen Dai Fan Feng Jian Zhang Jianyong Zheng 
supported by the National Natural Science Foundation of China(No.82072655);the Scientific and technological innovation team of Shaanxi Innovation Capability Support Plan(China)(No.2023-CX-TD-67);the Key R&D Plan of Shaanxi Province,China(No.2022SF-603).
SPP1^(+) macrophages have been identified as key players in the colorectal cancer(CRC) tumor microenvironment, but their function remains unclear. This study integrated single-cell and spatial transcriptomics with bul...
关键词：Colorectal cancer Immunotherapy Single-cell RNA sequencing Spatial transcriptomics SPP1þmacrophages 
Mechanism of AstragalosideⅣin Treatment of Renal Tubulointerstitial Fibrosis
《Chinese Journal of Integrative Medicine》2025年第5期474-480,共7页WANG Xin-ru LUAN Jing-xiang GUO Zhao-an 
Supported by Shandong Natural Science(No.ZR2022LZY005)。
Tubulointerstitial fibrosis(TIF)is one of the key indicators in evaluating the renal function of patients.Mild TIF can cause a vicious cycle of renal tubular glomerular injury and aggravate renal disease.Therefore,stu...
关键词：astragalosideⅣ tubulointerstitial fibrosis endoplasmic reticulum stress AUTOPHAGY MACROPHAGES Chinese medicine REVIEW 
Pioneering rheumatoid arthritis treatment:Magnesium ionmediated natural multi-component hydrogel synergistically regulates macrophage polarization,pannus formation,and bone regeneration
《Nano Research》2025年第4期346-363,共18页Luping Yang Xiang Zhang Yihang Zhao Zhijia Wang Xinru Tan Yuxin Zhang Zhiwei Wang Jihui Lu Shuchang Yao Jingyi Jiao Xuemei Huang Penglong Wang 
funded by the National Natural Science Foundation of China(Nos.82274072 and 82474059);the Beijing Municipal Natural Science Foundation(Nos.7242221 and 7254503);Beijing Nova Programme Interdisciplinary Cooperation Project(No.20240484578);the Fundamental Research Funds for the Central Universities(China,Nos.2023-JYB-JBZD-049,2022-XJKYQD-008,and 2024-JYB-XJSJJ004);Beijing Key Laboratory for Basic and Development Research on Chinese Medicine(Beijing,No.100102).
Rheumatoid arthritis(RA)is a chronic inflammatory autoimmune disease that affects millions of people worldwide.Current therapeutic drugs for RA are often limited by poor solubility,unresponsive to monotherapy,low bioa...
关键词：magnesium ion-mediated natural multi-component hydrogel rheumatoid arthritis macrophages polarization PI3K/AKT/NF-κB signaling pathway 
Microglia and brain macrophages are differentially associated with tumor necrosis in glioblastoma:A link to tumor progression
《Oncology Research》2025年第4期937-950,共14页CHRISTINA LOH YUQI ZHENG ISLAM ALZOUBI KIMBERLEY L.ALEXANDER MAGGIE LEE WEI-DONG CAI YANG SONG KERRIE MCDONALD ANNA K.NOWAK RICHARD B.BANATI MANUEL B.GRAEBER 
funding but aspects of this work(computer analysis)were supported by an Australian Research Council(ARC)grant,DP150104472(MBG);The Australian Genomics and Outcomes of Glioma project was funded by a Cancer Council NSW Strategic Research Partnership Grant.
Background:Microglia and brain macrophages contribute significantly to the tumor microenvironment in highly malignant glioblastoma where they are considered important drivers of tumor progression.A better understandin...
关键词：Bone marrow-derived macrophages(BMDM) CD163 Glioblastoma/glioma stem cells(GSCs) IBA1 MICROGLIA Multimodal whole slide analysis Tumor microenvironment 
Correction
《Biomedical and Environmental Sciences》2025年第4期525-526,共2页
It is hereby declared that the article entitled“miR-34c-3p Inhibits Nasopharyngeal Carcinoma Development via Inhibiting M2 Polarization of Macrophages”(Yuzi Ji,Yujie Wang,Jiqing Ma,Zhihua Yin,Fei Liu,Yanzi Zang,Guan...
关键词：biomedical environmental sciences nasopharyngeal carcinoma MACROPHAGES M polarization m polarization macrophages yuzi miR c p 
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