云南高校图书馆联盟文献共享服务平台- ALPHA-SYNUCLEIN

ALPHA-SYNUCLEIN: 作品数：90被引量：164H指数：6; 导出分析报告; 相关领域：医药卫生生物学更多>>; 相关作者：孙占芳江泓滕国生赵凌志柳明杰更多>>; 相关机构：中南大学首都医科大学长春工业大学吉林大学第二医院更多>>; 相关期刊：《Neuroimmunology and Neuroinflammation》《沈阳药科大学学报》《Neuroscience Bulletin》《Journal of Environmental Sciences》更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划广东省自然科学基金辽宁省科技厅博士启动基金更多>>

Adeno-associated viral vectors for modeling Parkinson's disease in non-human primates: 《Neural Regeneration Research》2026年第1期224-232,共9页Julia Chocarro JoséL.Lanciego; supported by grants PID2020-120308RB-I00 and PID2023-147802OB-I00 funded by MICIU/AEI/10.13039/501100011033;FEDER,UE,by Aligning Science Across Parkinson’s(ref.ASAP-020505)through the Michael J.Fox Foundation for Parkinson’s Research;by CiberNed Intramural Collaborative Projects(ref.PI2020/09);by the Spanish Fundación Mutua Madrile?a de Investigación Médica(to JLL)。; The development of clinical candidates that modify the natural progression of sporadic Parkinson's disease and related synucleinopathies is a praiseworthy endeavor,but extremely challenging.Therapeutic candidates that...; 关键词：adeno-associated viral vectors ALPHA-SYNUCLEIN DOPAMINE Lewy bodies NEURODEGENERATION NEUROMELANIN NEUROPATHOLOGY substantia nigra

Alpha-synuclein-induced upregulation of SKI family transcriptional corepressor 1: A new player in aging and Parkinson's disease?: 《Neural Regeneration Research》2026年第1期320-321,共2页Lauren Barrett Rebekah Bevans Aideen M.Sullivan Louise M.Collins Gerard W.O’Keeffe; supported by Science Foundation Ireland (Grant 19/FFP/6666),Cure Parkinson’s (Grant CP:GO01);a PhD studentship from the Anatomical Society。; SKI family transcriptional corepressor 1(SKOR1also known as LbxCor1, Fussel15, or CORL1), is a member of the SKI family of proteins and is transcribed from a protein-coding gene located on chromosome 15 in humans, tha...; 关键词：Alpha Cor AGING

Age-dependent alpha-synuclein aggregation and Lewy body formation in Parkinson's disease: 《Neural Regeneration Research》2025年第12期3533-3534,共2页Chun Chau Sung Kenny K.K.Chung; supported by the Innovation and Technology Commission (ITCPD/17-9);the Hong Kong Research Grants Council,China (GRF16104517)(to KKKC)。; Parkinson's disease (PD) is a common degenerative disorder that is becoming increasingly prevalent because of the global aging population.The exact cause of the disorder is unknown;however,recent studies have suggeste...; 关键词：PATHOGENESIS AGGREGATION BECOMING

Alpha-synuclein in mitochondrial dysfunction:opportunities or obstacles: 《Neural Regeneration Research》2025年第1期197-198,共2页Shermali Gunawardena; Recent work suggests a link betweenα-synuclein(α-syn)and mitochondrial dysfunction;however,the mechanisms of howα-syn influences mitochondrial function are still unclear.Most notably,whetherα-syn plays a direct ro...; 关键词：DYSFUNCTION HOMEOSTASIS ALPHA

Strain-dependent alpha-synuclein spreading in Parkinson's disease and multiple system atrophy被引量：1: 《Neural Regeneration Research》2024年第12期2581-2582,共2页Shuyu Zhang Paul Lingor; supported by Deutsche Forschungsgemeinschaft;EXC 2145 SyNergy;Grant No.390857198 (to PL)。; Parkinson's disease(PD) and atypical Parkinsonian syndromes,such as multiple system atrophy(MSA) and Dementia with Lewy bodies,are neurodegenerative movement disorders characterized by the accumulation of alphasynucle...; 关键词：ATROPHY ENDOGENOUS ATYPICAL

A systematic review of salivary biomarkers in Parkinson's disease被引量：2: 《Neural Regeneration Research》2024年第12期2613-2625,共13页Maria Ilenia De Bartolo Daniele Belvisi Romina Mancinelli Matteo Costanzo Claudia Caturano Giorgio Leodori Alfredo Berardelli Giovanni Fabbrini Giorgio Vivacqua; The search fo r reliable and easily accessible biomarkers in Parkinson's disease is receiving a growing emphasis,to detect neurodegeneration from the prodromal phase and to enforce disease-modifying therapies.Despite ...; 关键词：ALPHA-SYNUCLEIN AMYLOID-BETA autophagy DJ-1 NEURODEGENERATION NEUROINFLAMMATION Parkinson's disease salivary biomarkers tau

TFEB/LAMP2 contributes to PM_(0.2)-induced autophagy-lysosome dysfunction and alpha-synuclein dysregulation in astrocytes: 《Journal of Environmental Sciences》2024年第11期117-127,共11页Ben Li Ting Liu Yongmei Shen Jiangnan Qin Xiaohan Chang Meiqiong Wu Jianquan Guo Liangpo Liu Cailing Wei Yi Lyu Fengjie Tian Jinzhu Yin Tong Wang Wenping Zhang Yulan Qiu; supported by the National Science Foundation of China(No.21906100);the Applied Basic Research Project of Shanxi Province(Nos.201901D211333,201901D211327,and 202203021211246).; Atmospheric particulatematter(PM)exacerbates the risk factor for Alzheimer’s and Parkinson’s diseases(PD)by promoting the alpha-synuclein(α-syn)pathology in the brain.However,the molecular mechanisms of astrocytes ...; 关键词：PM_(0.2) ASTROCYTES α-Synuclein Autophagy-lysosome

Roles of neuronal lysosomes in the etiology of Parkinson’s disease被引量：1: 《Neural Regeneration Research》2024年第9期1981-1983,共3页Mattia Volta; supported by grants from Parkinson Canada,The Weston Brain Foundation and the Euregio Science Fund(to MV).; Therapeutic progress in neurodegenerative conditions such as Parkinson’s disease has been hampered by a lack of detailed knowledge of its molecular etiology.The advancements in genetics and genomics have provided fun...; 关键词：ALPHA-SYNUCLEIN autophagy LRRK2 LYSOSOME neuroprotection NEUROTRANSMISSION Parkinson’s disease Rit2 SYNAPSE

The Application of Analytical Techniques to Alpha-Synuclein in Parkinson’s Disease: 《American Journal of Analytical Chemistry》2024年第9期269-285,共17页Olatayo Adedayo Olahanmi; Parkinson’s disease (PD) is a progressive neurodegenerative disorder characterized by motor symptoms such as tremors, rigidity, and bradykinesia, as well as non-motor symptoms including cognitive impairment and mood ...; 关键词：Parkinson’s Disease ALPHA-SYNUCLEIN TECHNIQUES

Hydroxytyrosol and Parkinson's disease:protective actions against alpha-synuclein toxicity: 《Neural Regeneration Research》2024年第7期1427-1428,共2页Ruth Hornedo-Ortega Ana M.Espinosa-Oliva; Authors are also grateful to RHO’s postdoctoral contract (Ayuda IJC2020-045695-I financed by MCIN/AEI/10.13039/501100011033,European Union NextGeneration EU/PRTR)。; Parkinson’s disease:Parkinson’s disease(PD) is the second most prevalent neurodegenerative disease,after Alzheimer’s disease,affecting 1%of the general population over the age of 65years.According to data from the ...; 关键词：protective ALZHEIMER PREVALENCE

ALPHA-SYNUCLEIN