NEUROTRANSMISSION

作品数：36被引量：37H指数：3
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相关领域：医药卫生更多>>
相关作者：李名立倪培艳马小红沈露露汪洋更多>>
相关机构：东南大学四川大学更多>>
相关期刊：《World Journal of Biological Chemistry》《Advances in Bioscience and Biotechnology》《Journal of Semiconductors》《Neuroscience & Medicine》更多>>
相关基金：国家自然科学基金更多>>
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Decoding molecular mechanisms:brain aging and Alzheimer's disease
《Neural Regeneration Research》2025年第8期2279-2299,共21页Mahnoor Hayat Rafay Ali Syed Hammad Qaiser Mohammad Uzair Khalid Al-Regaiey Roaa Khallaf Lubna Abdullah Mohammed Albassam Imdad Kaleem Xueyi Wang Ran Wang Mehwish SBhatti Shahid Bashir 
The complex morphological,anatomical,physiological,and chemical mechanisms within the aging brain have been the hot topic of research for centuries.The aging process alters the brain structure that affects functions a...
关键词：Alzheimer’s disease brain aging cognitive health DEMENTIA molecular mechanisms neuronal activity NEUROPLASTICITY NEUROTRANSMISSION 
Lactate is a potentially harmful substitute for brain glucose fuel:consequences for metabolic restoration of neurotransmission
《Neural Regeneration Research》2025年第5期1403-1404,共2页Oliver Kann Lennart Soder Babak Khodaie 
The metabolite lactate (L-lactate) can be generated and released by diverse brain cells,including neurons,astrocytes,and oligodendrocytes (Kann,2023;Rae et al.,2024).Lactate production usually requires the degradation...
关键词：consequences FIGURE RESTORATION 
Graphene/F_(16)CuPc synaptic transistor for the emulation of multiplexed neurotransmission
《Journal of Semiconductors》2025年第1期215-223,共9页Zhipeng Xu Yao Ni Mingxin Sun Yiming Yuan Ning Wu Wentao Xu 
supported by the Shenzhen Science and Technology Program(No.JCYJ20210324121002008);the National Science Fund for Distinguished Young Scholars of China(No.T2125005);the National Key R&D Program of China(Nos.2022YFE0198200,2022YFA1204500,and 2022YFA1204504);the Natural Science Foundation of Tianjin(Nos.22JCYBJC01290 and 23JCQNJC01440);the Key Project of Natural Science Foundation of Tianjin(No.22JCZDJC00120);the Fundamental Research Funds for the Central Universities,Nankai University(Nos.BEG124901 and BEG124401);the Guangdong Basic and Applied Basic Research Foundation(No.2023A1515110319);the Key Science and Technology Program of Henan Province(No.242102210171).
We demonstrate a bipolar graphene/F_(16)CuPc synaptic transistor(GFST)with matched p-type and n-type bipolar properties,which emulates multiplexed neurotransmission of the release of two excitatory neurotransmitters i...
关键词：synaptic transistor dual excitatory channels fast-switching plasticity multiplexed neurotransmission 
A novel positive modulator of GABA_(A) receptor exhibiting antidepressive properties
《生理学报》2024年第5期677-690,共14页ZHENG Yin-Li SHEN Fu-Yi WANG Yang PAN Jing-Pei WANG Xian LI Tian-Yu DU Wei-Jia LIU Zhi-Qiang LI Yang GUO Fei 
γ-Aminobutyric acid(GABA) neurotransmission alterations have been implicated to play a role in depression pathogenesis. While GABA_(A) receptor positive allosteric modulators are emerging as promising in clinical pra...
关键词：ANTIDEPRESSANT GABAa receptor positive modulator NEUROTRANSMISSION 
Roles of neuronal lysosomes in the etiology of Parkinson’s disease被引量：1
《Neural Regeneration Research》2024年第9期1981-1983,共3页Mattia Volta 
supported by grants from Parkinson Canada,The Weston Brain Foundation and the Euregio Science Fund(to MV).
Therapeutic progress in neurodegenerative conditions such as Parkinson’s disease has been hampered by a lack of detailed knowledge of its molecular etiology.The advancements in genetics and genomics have provided fun...
关键词：ALPHA-SYNUCLEIN autophagy LRRK2 LYSOSOME neuroprotection NEUROTRANSMISSION Parkinson’s disease Rit2 SYNAPSE 
Rapid Antidepressant-Like Potential of Chaihu Shugan San Depends on Suppressing Glutamate Neurotransmission and Activating Synaptic Proteins in Hippocampus of Female Mice被引量：1
《Chinese Journal of Integrative Medicine》2024年第8期692-700,共9页LU Chao GAO Zi-wei XING Shan WANG Hui-hui HUANG Yun-ke ZHOU Hang WU Lei 
Supported by the National Natural Science Foundation of China(No.82174107,82304898);Jiangsu Provincial Administration of Traditional Chinese Medicine Fund(No.YB2020014);the Priority Academic Program Development of Jiangsu Higher Education Institutions(No.035062005001)。
Objective To explore the rapid antidepressant potential and the underlying mechanism of Chaihu Shugan San(CSS)in female mice.Methods Liquid chromatography mass spectrometry(LC-MS)/MS was used to determine the content ...
关键词：Chaihu Shugan San female rapid antidepressant potential N-methyl-D-aspartate receptor synapticprotein optogenetic Chinesemedicine 
神经损伤是轮胎橡胶衍生污染物6PPDQ引起虹鳟急性毒性的重要原因被引量：1
《Science Bulletin》2024年第5期621-635,共15页廖晓亮 陈智锋 欧诗平 刘倩怡 林善鸿 周嘉明 王玉洁 蔡宗苇 
supported by the National Natural Science Foundation of China(42177254);Science and Technology Planning Project of Guangdong Province(2020B1212030008)。
N-(1,3-dimethylbutyl)-N’-phenyl-p-phenylenediamine quinone(6PPDQ)has attracted significant attention due to its highly acute lethality to sensitive salmonids.However,studies investigating the mechanisms underlying it...
关键词：Emerging contaminant Rainbow trout NEUROTRANSMISSION Locomotor activity Molecular dynamics simulation 
Progress in pathogenesis and treatment of type A hepatic encephalopathy in acute liver failure:a comprehensive review
《Pharmacology Discovery》2024年第1期1-11,共11页Ye-Xin Xu He Wang Kang-Rui Hu Bo-Yu Shen Lin Xie Guang-Ji Wang Yan Liang 
supported by the National Nature Science Foundation of China(Grants 81974533,81530098).
Hepatic encephalopathy is a serious neuropsychiatric complication caused by liver failure,which is characterized by the development of cognitive and motor disorders into coma.Typically,hepatic encephalopathy can be di...
关键词：type A hepatic encephalopathy AMMONIA GLUTAMINE lactate inflammation blood-brain barrier neurotransmission 
Piezol channel activation facilitates baroreflex afferent neurotransmission with subsequent blood pressure reduction in control and hypertension rats被引量：2
《Acta Pharmacologica Sinica》2024年第1期76-86,共11页Chang-peng Cui Xue Xiong Jia-xin Zhao Dong-hong Fu Yan Zhang Peng-bo Ma Di Wu Bai-yan Li 
supported by the National Natural Science Foundation of China 81971326 and 81573431 to BYL;82204387 to DW.
Mechanosensitive cation channels such as Piezo1 and Piezo2 are activated by mechanical force like a starched wall of the aorta while blood pressure(BP)rising,which helps to elucidate the underlying mechanism of mechan...
关键词：blood pressure baroreflex afferent pathway aortic depressor nerve MECHANOSENSATION piezo channels Yoda1/GsMTx4 
A hybrid ambipolar synaptic transistor emulating multiplexed neurotransmission for motivation control and experience-dependent learning被引量：2
《Chinese Chemical Letters》2023年第2期557-562,共6页Zhipeng Xu Yao Ni Hong Han Huanhuan Wei Lu Liu Shuo Zhang Hao Huang Wentao Xu 
supported by the National Science Fund for Distinguished Young Scholars of China (No. T2125005);the Tianjin Science Foundation for Distinguished Young Scholars (No. 19JCJQJC61000);the Shenzhen Science and Technology Project (No. JCYJ20210324121002008)。
Artificial synapses with full synapse-like functionalities are of crucial importance for the implementation of neuromorphic computing and bioinspired intelligent systems. In particular, the development of artificial s...
关键词：Hybrid ambipolar Artificial synapse Dual excitatory channels Fast-switching plasticity Task-learning process 
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