MECHANOSENSATION

作品数：11被引量：21H指数：3
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相关领域：生物学更多>>
相关作者：闫致强更多>>
相关机构：复旦大学更多>>
相关期刊：《International Journal of Oral Science》《Open Journal of Biophysics》《Droplet》《Acta Pharmacologica Sinica》更多>>
相关基金：国家自然科学基金中国博士后科学基金北京市自然科学基金更多>>
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Characterization of auditory sensation in C.elegans
《Biophysics Reports》2024年第6期351-363,共13页Can Wang Elizabeth A.Ronan Adam J.Iliff Rawan Al-Ebidi Panagiota Kitsopoulos Karl Grosh Jianfeng Liu X.Z.Shawn Xu 
support from NIH T32 training grants;support from an NIH F32 grant;supported by grants from the NIDCD and NIGMS(to X.Z.S.X.)。
Research using the model organism nematode C.elegans has greatly facilitated our understanding of sensory biology,including touch,olfaction,taste,vision and proprioception.While hearing had long been considered to be ...
关键词：C.elegans HEARING AUDITION MECHANOSENSATION MECHANOSENSORY 
Magnetic nanofluid-based liquid marble for a self-powered mechanosensation
《Droplet》2024年第3期57-64,共8页Manhui Chen Ziwei Liu Yike Li Shanfei Zhang Peng Chen Pengyu Zhang Bin Su 
National Natural Science Foundation of China,Grant/Award Number:52375336。
Magnetic nanofluid possesses the characteristic of interfering with the propagation of the magnetic field,endowing it with the sensing property in motion.However,the residual adhesion of magnetic nanofluid as it flows...
关键词：WEAR FLUID PROPERTY 
Piezol channel activation facilitates baroreflex afferent neurotransmission with subsequent blood pressure reduction in control and hypertension rats被引量：2
《Acta Pharmacologica Sinica》2024年第1期76-86,共11页Chang-peng Cui Xue Xiong Jia-xin Zhao Dong-hong Fu Yan Zhang Peng-bo Ma Di Wu Bai-yan Li 
supported by the National Natural Science Foundation of China 81971326 and 81573431 to BYL;82204387 to DW.
Mechanosensitive cation channels such as Piezo1 and Piezo2 are activated by mechanical force like a starched wall of the aorta while blood pressure(BP)rising,which helps to elucidate the underlying mechanism of mechan...
关键词：blood pressure baroreflex afferent pathway aortic depressor nerve MECHANOSENSATION piezo channels Yoda1/GsMTx4 
Premature aging of skeletal stem/progenitor cells rather than osteoblasts causes bone loss with decreased mechanosensation被引量：3
《Bone Research》2023年第3期560-573,共14页Ruici Yang Dandan Cao Jinlong Suo Lingli Zhang Chunyang Mo Miaomiao Wang Ningning Niu Rui Yue Weiguo Zou 
supported by the National Natural Science Foundation of China (NSFC) (82230082,81991512 to W.Z.,82202742 to J.S.,82070108 to R.Y.);the National Key Research and Development Program of China (2022YFA0806600 to W.Z.,2022YFA1103200 to R.Y.);CAS Project for Young Scientists in Basic Research (YSBR077 to W.Z.)。
A distinct population of skeletal stem/progenitor cells(SSPCs)has been identified that is indispensable for the maintenance and remodeling of the adult skeleton.However,the cell types that are responsible for age-rela...
关键词：SENSATION PROGENITOR mec 
Mechanosensation of osteocyte with collagen hillocks and primary cilia under pressure and electric field stimulation
《Acta Mechanica Sinica》2022年第3期172-186,I0004,共16页Yan Wang Chaoxin Li Hao Dong Jianhao Yu Yang Yan Xiaogang Wu Yanqin Wang Pengcui Li Xiaochun Wei Weiyi Chen 
supported by the National Natural Science Foundation of China(Grant Nos.11972242,11632013,11702183);China Postdoctoral Science Foundation(Grant No.2020M680913).
Mechanosensors are the most important organelles for osteocytes to perceive the changes of surrounding mechanical environment.To evaluate the biomechanical effectiveness of collagen hillock,cell process and primary·c...
关键词：OSTEOCYTE Cell Process Primary Cilium Collagen Hillock Finite Element 
Measurement of dynamic membrane mechanosensation using optical tweezers
《Journal of Molecular Cell Biology》2021年第6期455-457,共3页Xuanling Li Xing Liu Xiaoyu Song Yinmei Li Ming Li Haowei Wang 
This work was financially supported by the grants from the National Natural Science Foundation of China(31870759,61535011,and 21922706);the Fundamental Research Funds for the Central University(WK9110000025);the National Cancer Center Climbing Funds(NCC201812B036);Anhui Provincial Natural Science Foundation(2008085MH288 and 1908085MC64);the New Coronavirus Infection Emergency Science and Technology Project,Clinical Research Hospital of Chinese Academy of Sciences(YD9110002010).]。
Many cellular processes are orchestrated by dynamic changes in the plasma membrane to form membrane projections and endocytic compartments in response to extracellular cue changes.Our previous studies show that post-t...
关键词：DYNAMIC CURVATURE TRANSLATIONAL 
Polymodal Functionality of C. elegans OLL Neurons in Mechanosensation and Thermosensation
《Neuroscience Bulletin》2021年第5期611-622,共12页Yuedan Fan Wenjuan Zou Jia Liu Umar Al-Sheikh Hankui Cheng Duo Duan Du Chen Siyan Liu Luyi Chen Jilei Xu Firdosh Ruhomutally Lijun Kang 
supported by the National Natural Science Foundation of China (31471023, 31771113, and 31800878);the China Postdoctoral Science Foundation (2020M671695, 2020T130592, 2019T120505, and 2018M640551)。
Sensory modalities are important for survival but the molecular mechanisms remain challenging due to the polymodal functionality of sensory neurons. Here, we report the C. elegans outer labial lateral(OLL) sensilla se...
关键词：Polymodal sensory neuron MECHANOSENSATION Thermosensation Sodium channel Cold receptor OLL neurons 
Bench-to-bedside strategies for osteoporotic fracture: from osteoimmunology to mechanosensation被引量：11
《Bone Research》2019年第3期259-271,共13页Yong Xie Licheng Zhang Qi Xiong Yanpan Gao Wei Ge Peifu Tang 
supported by the National Natural Science Foundation of China (81772369, 81401809, 81373150);CAMS Innovation Fund for Medical Sciences (CIFMS, 2017-I2M-3-001);supported by the Beijing Nova program (Z171100001117110);supported by the Beijing Natural Science Foundation (7192127)
Osteoporosis is characterized by a decrease in bone mass and strength, rendering people prone to osteoporotic fractures caused by low-energy forces. The primary treatment strategy for osteoporotic fractures is surgery...
关键词：COMMINUTED SKELETAL PRONE to 
Loss of Aβ-nerve endings associated with the Merkel cell-neurite complex in the lesional oral mucosa epithelium of lichen planus and hyperkeratosis被引量：2
《International Journal of Oral Science》2016年第1期32-38,共7页Daniela Calderon Carrion Yiiksel Korkmaz Britta Cho Marion Kopp Wilhelm Bloch Klaus Addicks Wilhelm Niedermeier 
The Merkel cell-neurite complex initiates the perception of touch and mediates Ap slowly adapting type I responses. Lichen planus is a chronic inflammatory autoimmune disease with T-cell-mediated inflammation, whereas...
关键词：Aβ-nerve fibres HYPERKERATOSIS lichen planus MECHANOSENSATION Merkel cell-neurite complex 
Demystifying Mechanosensitive Piezo Ion Channels被引量：3
《Neuroscience Bulletin》2016年第3期307-309,共3页X.Z.Shawn Xu 
Mechanosensitive channels mediate touch,hearing,proprioception,and blood pressure regulation.Piezo proteins,including Piezo1 and Piezo2,represent a new class of mechanosensitive channels that have been reported to pla...
关键词：MECHANOSENSATION MECHANOSENSORY echanotransduction MECHANICAL CRYO-EM Piezo 
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