Measurement of dynamic membrane mechanosensation using optical tweezers  

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作  者:Xuanling Li Xing Liu Xiaoyu Song Yinmei Li Ming Li Haowei Wang 

机构地区:[1]Department of Optics and Optical Engineering,University of Science and Technology of China and Hefei National Laboratory for Physical Sciences at the Microscale,Hefei,China [2]MOE Key Laboratory for Membraneless Organelles&Cellular Dynamics,Anhui Key Laboratory for Cellular Dynamics and Chemical Biology,Hefei,China [3]Department of Laboratory Diagnostics,the First Affiliated Hospital,University of Science and Technology of China,Hefei,China

出  处:《Journal of Molecular Cell Biology》2021年第6期455-457,共3页分子细胞生物学报(英文版)

基  金:This work was financially supported by the grants from the National Natural Science Foundation of China(31870759,61535011,and 21922706);the Fundamental Research Funds for the Central University(WK9110000025);the National Cancer Center Climbing Funds(NCC201812B036);Anhui Provincial Natural Science Foundation(2008085MH288 and 1908085MC64);the New Coronavirus Infection Emergency Science and Technology Project,Clinical Research Hospital of Chinese Academy of Sciences(YD9110002010).]。

摘  要:Many cellular processes are orchestrated by dynamic changes in the plasma membrane to form membrane projections and endocytic compartments in response to extracellular cue changes.Our previous studies show that post-translational modifications of ACAP4 regulate membrane dynamics and curvature in response to epidermal growth factor and chemokine(C−C motif)ligand 18 stimulation(Zhao et al.,2013;Song et al.,2018).

关 键 词:DYNAMIC CURVATURE TRANSLATIONAL 

分 类 号:Q25[生物学—细胞生物学]

 

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