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PROGENITOR: 作品数：264被引量：592H指数：12; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：王燕张蕾刘卫红王丽华林燕更多>>; 相关机构：第四军医大学西京医院上海交通大学医学院附属仁济医院北京市中医研究所武汉大学更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划中国博士后科学基金广东省自然科学基金更多>>

A systematic review of progenitor survival and maturation in Parkinsonian models: 《Neural Regeneration Research》2025年第11期3172-3178,共7页Giulia Comini Eilís Dowd; supported by research grants from the Michael J Fox Foundation for Parkinson’s Research(grant numbers:17244 and 023410);Science Foundation Ireland(Grant Numbers:19/FFP/6554)(to ED)。; Stem cell-based brain repair is a promising emergent therapy for Parkinson's disease based on years of foundational research using human fetal donors as a cell source.Unlike current therapeutic options for patients,th...; 关键词：cell replacement therapy DIFFERENTIATION embryonic stem cells GRAFT induced pluripotent stem cells Parkinson's disease SURVIVAL TRANSPLANT

Properdin deficiency associated with systemic meningococcal disease due to a novel p.Cys337Arg pathogenic variant: 《Genes & Diseases》2024年第6期43-46,共4页Laura Gonzalez-Sanchez Ana Mei Agudo Anne Van Den Rym Maria Isabel Begiristain Alazne Saizar Rebeca Perez de Diego Pilar Nozal Alberto Lopez-Lera Margarita Lopez-Trascasa Fernando Corvillo; funded by the Spanish Instituto de Salud Carlos III (ISCIII)and the European Regional Development Fund European Union (grant Pl15-00255);by the Spanish Autonomous Region ofMadrid (Complement II-CMnetwork;S2017/BMD-3673);F.C.was awarded a research fellowship by the Asociacion Internacional de Familiares y Afectados de Lipodistrofias (AELIP).; Properdin(FP)is a soluble glycoprotein with a key role in the regulation of the alternative pathway(AP)of the complement system.1 Neutrophils are the main source of FP,although monocytes,bone marrow progenitors,and T ...; 关键词：Xp11.2 GLYCOPROTEIN PROGENITOR

Glial progenitor heterogeneity and plasticity in the adult spinal cord: 《Neural Regeneration Research》2024年第12期2567-2568,共2页Haichao Wei Jia Qian Wu; supported by grants from the NIH,United States (R01AG078728-01 and R21NS113068);Fund-the UTHSC Senator Lloyd and B.A.Bentsen Center for Stroke Research (to JQW)。; Glial progenitor cells were reported to have the capacity to generate various types of cells in both the central nervous system(CNS)and peripheral nervous system.Glial progenitor cells can respond to diverse environme...; 关键词：functions PLASTICITY thoroughly

Unlocking lung regeneration:insights into progenitor cell dynamics and metabolic control: 《Cell Regeneration》2024年第1期21-38,共18页Jiaying Yang Yawen Li Ying Huang Huaiyong Chen Pengfei Sui; National Key Research and Development Program of China 2022YFA0806200;“Strategic Priority Research Program”of the Chinese Academy of Sciences(CAS)(XDB1030000);National Natural Science Foundation of China 82070042;CAS Youth Interdisciplinary Team(to P.S.).; Regenerative responses are particularly important in the lungs,which are critical for gas exchange and frequently challenged by environmental insults.The lung progenitor cells play a central role in the lung regenerat...; 关键词：Lung repair and regeneration Lung progenitor cells Cell metabolism Cell fate decision

Supragel-mediated efficient generation of pancreatic progenitor clusters and functional glucose-responsive islet-like clusters: 《Bioactive Materials》2024年第11期1-14,共14页Hongmeng Ma Lilin Xu Shengjie Wu Songdi Wang Jie Li Sifan Ai Zhuangzhuang Yang Rigen Mo Lei Lin Yan Li Shusen Wang Jie Gao Chen Li Deling Kong; National Key Technologies Research and Development Program of China(2020YFA0803701);National Natural Science Foundation of China(81921004,T2122019);CAMS Innovation Fund for Medical Sciences(2021–12M-1-052).; Although several synthetic hydrogels with defined stiffness have been developed to facilitate the proliferation and maintenance of human pluripotent stem cells(hPSCs),the influence of biochemical cues in lineage-speci...; 关键词：Synthetic hydrogel Stem cell differentiation Mechanical stiffness Islet clusters

FGF signaling modulates mechanotransduction/WNT signaling in progenitors during tooth root development: 《Bone Research》2024年第3期582-594,共13页Fei Pei Tingwei Guo Mingyi Zhang Li Ma Junjun Jing Jifan Feng Thach-Vu Ho Quan Wen Yang Chai; supported by funding from the National Institute of Dental and Craniofacial Research,National Institutes of Health (R01 DE022503 and R01 DE012711 to Yang Chai)。; Stem/progenitor cells differentiate into different cell lineages during organ development and morphogenesis.Signaling pathway networks and mechanotransduction are important factors to guide the lineage commitment of s...; 关键词：PROGENITOR MEC FACIAL

Rejuvenation of BMSCs senescence by pharmacological enhancement of TFEB-mediated autophagy alleviates aged-related bone loss and extends lifespan in middle aged mice: 《Bone Research》2024年第3期661-674,共14页Ziwei Luo Wanyi Wei Dawei Qiu Zixia Su Liangpu Liu Honghai Zhou Hao Cui Li Yang; supported by grants from Science and Technology Planning Project of Guangxi Zhuang Autonomous Region (Guike AD19245094,AD19245096);Doctoral Foundation of Guangxi University of Chinese Medicine (XP018148);Guangxi Key Laboratory of Efficacy Study on Chinese Materia Medica,2020 (20-065-38)。; Bone marrow stromal/stem cells(BMSCs)are generally considered as common progenitors for both osteoblasts and adipocytes in the bone marrow,but show preferential differentiation into adipocytes rather than osteoblasts ...; 关键词：SENILE osteoporosis PROGENITOR

Extramedullary neutrophil progenitors: Quo Vadis?: 《Cellular & Molecular Immunology》2024年第8期932-934,共3页Leo Koenderman Nienke Vrisekoop; It is textbook knowledge that the thymus is the factory of naïve T cells.Counterintuitively,naïve T cell production by the thymus is well-known to atrophy during acute inflammation[1].Pérez and colleagues in this iss...; 关键词：intuitive INFLAMMATION PROGENITOR

Aberrant adult neurogenesis in intractable epilepsy:can GABAergic progenitor transplantation normalize this process?: 《Neural Regeneration Research》2024年第7期1419-1420,共2页Muhammad N.Arshad Janice R.Naegele; Temporal lobe epilepsy(TLE) is a common type of focal epilepsy characterized by seizure foci within the temporal lobes.While surgical resection of the foci is an established and effective approach for controlling seiz...; 关键词：EPILEPSY PROGENITOR seizures

Combining neural progenitor cell transplant and rehabilitation for enhanced recovery after cervical spinal cord injury: 《Neural Regeneration Research》2024年第7期1433-1434,共2页Camila M.Freria Paul Lu; supported by the Veterans Administration (I01RX002264-01A2)(to PL);Wings For Life (WFL-US-10/21)(to CMF)。; Efforts to promote recovery of function after human spinal cord injury(SCI) will likely require interventions to rgeting the corticospinal tract(CST) motor system:the most important pathway for voluntary motor control...; 关键词：CERVICAL PROGENITOR INJURY

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