supported by core funding provided by Temasek Life Sciences Laboratory(to CTO)。
Apolipoprotein E has diverse functions in neurons:Apolipoprotein E(ApoE)is a glycoprotein that primarily regulates lipid metabolism and transport in the central nervous system.There are three predominant human ApoE pr...
Dear Editor,Myelin oligodendrocyte glycoprotein(MOG)is a minor component of myelin,expressed on the external surface of oligodendrocytes in the central nervous system(CNS)[1].Anti-MOG antibodies(MOG-ab)have been impli...
Mucosal healing in Crohn’s disease(CD)has been established as a crucial target of treatment,leading to long term remission and decrease in complication rates.Endoscopy still serves as the gold standard for assessment...
The study by Ohno et al provides valuable insights into the role of leucine-rich alpha-2-glycoprotein(LRG)as a potential biomarker for identifying small bowel lesions in Crohn's disease(CD).However,several methodologi...
Supported by the Grants-in-Aid for Scientific Research from the Ministry of Education,Culture,Sports,Science,and Technology of Japan,No.21K15947 and No.23K07435.
BACKGROUND Achievement of endoscopic healing(EH)is significant in the clinical practice of inflammatory bowel disease as it is correlated with improved prognosis.Existing biomarkers,including C-reactive protein(CRP),h...
funded by the Spanish Instituto de Salud Carlos III (ISCIII)and the European Regional Development Fund European Union (grant Pl15-00255);by the Spanish Autonomous Region ofMadrid (Complement II-CMnetwork;S2017/BMD-3673);F.C.was awarded a research fellowship by the Asociacion Internacional de Familiares y Afectados de Lipodistrofias (AELIP).
Properdin(FP)is a soluble glycoprotein with a key role in the regulation of the alternative pathway(AP)of the complement system.1 Neutrophils are the main source of FP,although monocytes,bone marrow progenitors,and T ...
supported by the National Key Research and Development Program of China(grant number 2023YFC2306002);National Science and Technology Major Projects(grant number 2017ZX10104001-005-010);CAMS Innovation Fund for Medical Sciences(CIFMS)(Grant Number 2019-I2M-5-026);Funding for Reform and Development of Beijing Municipal Health Commission.
Respiratory syncytial virus(RSV)is a significant cause of acute lower respiratory tract infection(ALRTI)in children underfive years of age.Between 2017 and 2021,396 complete sequences of the RSV F gene were obtained fro...
supported by grants from the National Natural Science Foundation of China(Nos.32000998 and 32201240);The Young Elite Scientists Sponsorship Program by Henan Association for Science and Technology(No.2022HYTP046);the China Postdoctoral Science Foundation(No.2021TQ0298);Science and Technology Development Project of Henan Province(Nos.222102310525,232102310351);National College Students’innovation and entrepreneurship training program(No.202310459197).
Breast cancer remains a leading cause of morbidity and mortality among women worldwide,emphasizing the urgent need for enhanced diagnostic and therapeutic approaches.Leucine-rich-alpha-2-glycoprotein 1(LRG1)has emerge...
Nasopharyngeal carcinoma(NPC)is a malignant tumor arising from the nasopharyngeal epithelium.It consists of undifferentiated squamous cells in the nasopharynx.This type of epithelial cell neoplasm is globally distribu...