A case of post-infectious anti-myelin oligodendrocyte glycoprotein antibody-positive optic neuritis  

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作  者:Yu Bin Son Kye-Hyung Kim Hee-Young Choi Hyeshin Jeon 

机构地区:[1]Department of Ophthalmology,Pusan National University School of Medicine,Busan 49241,Republic of Korea [2]Biomedical Research Institute,Pusan National University Hospital,Busan 49241,Republic of Korea [3]Department of Internal Medicine,Pusan National University School of Medicine,Busan 49241,Republic of Korea

出  处:《International Journal of Ophthalmology(English edition)》2025年第4期751-752,共2页国际眼科杂志(英文版)

摘  要:Dear Editor,Myelin oligodendrocyte glycoprotein(MOG)is a minor component of myelin,expressed on the external surface of oligodendrocytes in the central nervous system(CNS)[1].Anti-MOG antibodies(MOG-ab)have been implicated in the demyelinating process and are considered unique biomarkers for a group of heterogeneous autoimmune inflammatory CNS diseases known as MOG-associated disorder(MOGAD)[1].MOGAD can present with a range of clinical manifestations,including optic neuritis,transverse myelitis,acute disseminating encephalomyelitis,and brainstem or cerebral encephalitis[1].Optic neuritis is the most common clinical feature of MOGAD in adults,typically manifesting as steroid-sensitive,recurrent,bilateral optic neuritis with optic disc swelling[1].

关 键 词:NEURITIS MYELIN GLYCOPROTEIN 

分 类 号:R74[医药卫生—神经病学与精神病学]

 

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