MYELIN

作品数：165被引量：310H指数：9
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Is age-related myelinodegenerative change an initial risk factor of neurodegenerative diseases?
《Neural Regeneration Research》2026年第2期648-658,共11页Shuangchan Wu Jun Chen 
supported by grants from Guangdong Basic and Applied Basic Research Foundation,No.2021A1515110801(to SW);the National Natural Science Foundation of China,No.82301511(to SW);“Double First-Class”Construction Project of NPU,Nos.0515023GH0202320(to JC),0515023SH0201320(to JC)and 973 Program,No.2011CB504100(to JC).
Myelination,the continuous ensheathment of neuronal axons,is a lifelong process in the nervous system that is essential for the precise,temporospatial conduction of action potentials between neurons.Myelin also provid...
关键词：aging Alzheimer’s disease multiple sclerosis MYELIN myelin-axon metabolite crosstalk myelinodegeneration neurodegenerative disease OLIGODENDROCYTE Parkinson’s disease white matter 
Oligodendroglial heterogeneity in health,disease,and recovery:deeper insights into myelin dynamics
《Neural Regeneration Research》2025年第11期3179-3192,共14页Pieter-Jan Serneels Julie D.De Schutter Lies De Groef Lieve Moons Steven Bergmans 
supported by KU Leuven Internal Funding(C3/21/012);the Research Foundation Flanders(FWO G092222N)(to LM)。
Decades of research asserted that the oligodendroglial lineage comprises two cell types:oligodendrocyte precursor cells and oligodendrocytes.However,recent studies employing single-cell RNA sequencing techniques have ...
关键词：animal models DEMYELINATION fish MAMMALS multiple sclerosis MYELIN neurodegeneration OLIGODENDROCYTES oligodendroglial lineage REMYELINATION 
Crosstalk between androgen signaling and the chemokine receptor CXCR4:a novel strategy to promote myelin regeneration
《Neural Regeneration Research》2025年第9期2581-2582,共2页Marianne Bardy-Lagarde Narimène Asbelaoui Abdel Mouman Ghoumari 
supported by a grant from the French Multiple Sclerosis Society(ARSEP,Grant Number:R20163LL)(to AMG)。
Multiple sclerosis(MS)is the most common chronic disease of the central nervous system(CNS)in young adults and represents the first cause of severe handicap,originally non-traumatic(Oh et al.,2018).MS is chara cterize...
关键词：MYELIN CXCR4 
Perilipin-2 mediates ferroptosis in oligodendrocyte progenitor cells and myelin injury after ischemic stroke
《Neural Regeneration Research》2025年第7期2015-2028,共14页Jian Yang Jiang Wu Xueshun Xie Pengfei Xia Jinxin Lu Jiale Liu Lei Bai Xiang Li Zhengquan Yu Haiying Li 
supported by the National Natural Science Foundation of China,Nos.82071307(to HL),82271362(to HL),82171294(to JW),82371303(to JW),and 82301460(to PX);the Natural Science Foundation of Jiangsu Province,No.BK20211552(to HL);Suzhou Medical Technology Innovation Project-Clinical Frontier,No.SKY2022002(to ZY);the Science and Education Foundation for Health of Suzhou for Youth,No.KJXW2023001(to XL)。
Differentiation of oligodendrocyte progenitor cells into mature myelin-forming oligodendrocytes contributes to remyelination.Failure of remyelination due to oligodendrocyte progenitor cell death can result in severe n...
关键词：BIOINFORMATICS bulk RNA sequencing ferroptosis ischemic stroke myelin injury oligodendrocyte progenitor cell perilipin-2 single-cell RNA sequencing 
Harnessing therapeutic potential of induced pluripotent stem cell–derived endothelial cells for remyelination in the central nervous system
《Neural Regeneration Research》2025年第6期1715-1716,共2页Dan Ma Nona Pop 
supported by a grant from Aston University,Birmingham,UK (to DM)。
Myelin is the protective sheath surrounding nerve fibers, and its damage(demyelination) occurs in many central nervous system(CNS) diseases, including multiple sclerosis(MS), traumatic injury, neurodegenerative diseas...
关键词：MYELIN protective DISEASES 
Role of copper in central nervous system physiology and pathology
《Neural Regeneration Research》2025年第4期1058-1068,共11页Martina Locatelli Cinthia Farina 
Copper is a transition metal and an essential element for the organism,as alterations in its homeostasis leading to metal accumulation or deficiency have pathological effects in several organs,including the central ne...
关键词：ASTROCYTES central nervous system COPPER CUPRIZONE multiple sclerosis MYELIN neurodegenerative disorders 
A case of post-infectious anti-myelin oligodendrocyte glycoprotein antibody-positive optic neuritis
《International Journal of Ophthalmology(English edition)》2025年第4期751-752,共2页Yu Bin Son Kye-Hyung Kim Hee-Young Choi Hyeshin Jeon 
Dear Editor,Myelin oligodendrocyte glycoprotein(MOG)is a minor component of myelin,expressed on the external surface of oligodendrocytes in the central nervous system(CNS)[1].Anti-MOG antibodies(MOG-ab)have been impli...
关键词：NEURITIS MYELIN GLYCOPROTEIN 
Polyethylene glycol has immunoprotective effects on sciatic allografts, but behavioral recovery and graft tolerance require neurorrhaphy and axonal fusion
《Neural Regeneration Research》2025年第4期1192-1206,共15页Tyler A.Smith Liwen Zhou Cameron L.Ghergherehchi Michelle Mikesh Cathy Z.Yang Haley O.Tucker JuliAnne Allgood Jared S.Bushman George D.Bittner 
supported by grants from the Lone Star Paralysis Foundation,NIH R01NS081063;Department of Defense award W81XWH-19-2-0054 to GDB;supported by University of Wyoming Startup funds,Department of Defense grant W81XWH-17-1-0402;the University of Wyoming Sensory Biology COBRE under National Institutes of Health(NIH)award number 5P20GM121310-02;the National Institute of General Medical Sciences of the NIH under award number P20GM103432 to JSB。
Behavioral recovery using(viable)peripheral nerve allografts to repair ablation-type(segmental-loss)peripheral nerve injuries is delayed or poor due to slow and inaccurate axonal regeneration.Furthermore,such peripher...
关键词：allograft rejection AXOTOMY macrophage MYELIN nerve repair polyethylene glycol(PEG) sciatic nerve T cell transplantation Wallerian degeneration 
Autophagy in Oligodendrocyte Lineage Cells Controls Oligodendrocyte Numbers and Myelin Integrity in an Age‑dependent Manner
《Neuroscience Bulletin》2025年第3期374-390,共17页Hong Chen Gang Yang De‑En Xu Yu‑tong Du Chao Zhu Hua Hu Li Luo Lei Feng Wenhui Huang Yan‑Yun Sun Quan‑Hong Ma 
supported by the STI2030-Major Projects(2021ZD0204001);the National Natural Science Foundation of China(92049120,81870897,81271424,81671111,and 62475179);the Sino German Cooperation and Exchange Project(M-0679);the Guangdong Key Project in the Development of New Tools for the Diagnosis and Treatment of Autism(2018B030335001);the Natural Science Foundation of Jiangsu Province(BK20181436);the Priority Academic Program Development of Jiangsu Higher Education Institutions,the Jiangsu Key Laboratory of Translational Research and Therapy for Neuro-Psycho-Diseases(BM2013003);Suzhou International Joint Laboratory for Diagnosis and Treatment of Brain Diseases,Suzhou Science and Technology Plan Medical and Health Care Science and Technology Innovation Applied Basic Research(SKY2022161);the Research Project of Neurological Diseases in the Second Affiliated Hospital of Soochow University Research Center(ND2023A01);Boxi clinical research project of The First Affiliated Hospital of Soochow University(BXQN202204);Suzhou Science&Technology Projects for People's Livelihood(SKY2021065);Wuxi Municipal Health Commission(M202204).
Oligodendrocyte lineage cells, including oligodendrocyte precursor cells (OPCs) and oligodendrocytes (OLs), are essential in establishing and maintaining brain circuits. Autophagy is a conserved process that keeps the...
关键词：AUTOPHAGY Oligodendrocyte precursor cells OLIGODENDROCYTES MYELINATION Myelin proteins Turnover Degradation 
Correction to:Autophagy in Oligodendrocyte Lineage Cells Controls Oligodendrocyte Numbers and Myelin Integrity in an Age‑dependent Manner
《Neuroscience Bulletin》2025年第3期547-548,共2页
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