Crosstalk between androgen signaling and the chemokine receptor CXCR4:a novel strategy to promote myelin regeneration  

作　　者：Marianne Bardy-Lagarde Narimène Asbelaoui Abdel Mouman Ghoumari 

机构地区：[1]UMR1195,“Diseases and Hormones of the Nervous System”,Inserm and University Paris-Saclay,Kremlin-Bicêtre,France

出　　处：《Neural Regeneration Research》2025年第9期2581-2582,共2页中国神经再生研究（英文版）

基　　金：supported by a grant from the French Multiple Sclerosis Society(ARSEP,Grant Number:R20163LL)(to AMG)。

摘　　要：Multiple sclerosis(MS)is the most common chronic disease of the central nervous system(CNS)in young adults and represents the first cause of severe handicap,originally non-traumatic(Oh et al.,2018).MS is chara cterized by the infiltration of auto reactive lymphocytes specific to myelin through the blood-brain barrier,which results in the appearance of inflammatory demyelinating lesions caused by the death of the central nervous system myelinating cells,oligodendrocytes(Oh et al.,2018).There is a prevalence sexual with a ratio of three times more affected women than men.

关 键 词：MYELIN CXCR4 

分 类 号：R744.51[医药卫生—神经病学与精神病学]