云南高校图书馆联盟文献共享服务平台- REMYELINATION

REMYELINATION: 作品数：75被引量：208H指数：9; 导出分析报告; 相关领域：医药卫生生物学更多>>; 相关作者：张蕾赵亮亮石亚伟何成更多>>; 相关机构：郑州市骨科医院第二军医大学山西大学更多>>; 相关期刊：《Chinese Journal of Traumatology》《Science China(Life Sciences)》《Acta Pharmacologica Sinica》《神经损伤与功能重建》更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划北京市自然科学基金中国博士后科学基金更多>>

Oligodendroglial heterogeneity in health,disease,and recovery:deeper insights into myelin dynamics: 《Neural Regeneration Research》2025年第11期3179-3192,共14页Pieter-Jan Serneels Julie D.De Schutter Lies De Groef Lieve Moons Steven Bergmans; supported by KU Leuven Internal Funding(C3/21/012);the Research Foundation Flanders(FWO G092222N)(to LM)。; Decades of research asserted that the oligodendroglial lineage comprises two cell types:oligodendrocyte precursor cells and oligodendrocytes.However,recent studies employing single-cell RNA sequencing techniques have ...; 关键词：animal models DEMYELINATION fish MAMMALS multiple sclerosis MYELIN neurodegeneration OLIGODENDROCYTES oligodendroglial lineage REMYELINATION

EZH2-dependent myelination following sciatic nerve injury: 《Neural Regeneration Research》2025年第8期2382-2394,共13页Hui Zhu Li Mu Xi Xu Tianyi Huang Ying Wang Siyuan Xu Yiting Wang Wencong Wang Zhiping Wang Hongkui Wang Chengbin Xue; financially supported by the National Natural Science Foundation of China,Nos.82172104(to CX),81873767(to HZ);a grant from Jiangsu Provincial Research Hospital,Nos.YJXYY202204(to HZ),YJXYY202204-ZD04(to HZ);a grant from Jiangsu Provincial Key Medical Center;Jiangsu Provincial Medical Innovation Center,No.CXZX202212;Jiangsu Provincial Medical Key Discipline,No.ZDXK202240;the Priority Academic Program Development of Jiangsu Higher Education Institutions(PAPD);Technology Project of Nantong,No.MS22022008(to HZ);Postgraduate Research&Practice Innovation Program of Jiangsu Province,No.SJCX21_1457(to WW)。; Demyelination and remyelination have been major focal points in the study of peripheral nerve regeneration following peripheral nerve injury.Notably,the gene regulatory network of regenerated myelin differs from that ...; 关键词：DEMYELINATION EZH2 MYELINATION peripheral nerve injury PRC2 REMYELINATION Schwann cells sciatic nerve crush sciatic nerve transection

Harnessing therapeutic potential of induced pluripotent stem cell–derived endothelial cells for remyelination in the central nervous system: 《Neural Regeneration Research》2025年第6期1715-1716,共2页Dan Ma Nona Pop; supported by a grant from Aston University,Birmingham,UK (to DM)。; Myelin is the protective sheath surrounding nerve fibers, and its damage(demyelination) occurs in many central nervous system(CNS) diseases, including multiple sclerosis(MS), traumatic injury, neurodegenerative diseas...; 关键词：MYELIN protective DISEASES

Trametinib,an anti-tumor drug,promotes oligodendrocytes generation and myelin formation: 《Acta Pharmacologica Sinica》2024年第12期2527-2539,共13页Ying Yang Na Suo Shi-hao Cui Xuan Wu Xin-yue Ren Yin Liu Ren Guo Xin Xie; supported by grants from the Ministry of Science and Technology of China(STI2030 Major Projects 2022ZD0204700 to XX,2022YFA1104700 to XX);the National Natural Science Foundation of China(82121005 to XX,82003723 to NS,82330113 to XX,32000504 to RG);Youth Innovation Promotion Association of the Chinese Academy of Sciences grants(2023295 to NS,2022280 to RG);Taishan Scholars Program to XX。; Oligodendrocytes(OLs)are differentiated from oligodendrocyte precursor cells(OPCs)in the central nervous system(CNS).Demyelination is a common feature of many neurological diseases such as multiple sclerosis(MS)and le...; 关键词：oligodendrocyte differentiation oligodendrocyte progenitor cell REMYELINATION trametinib MEK inhibitor MEK/ERK pathway

Overview of emerging therapies for demyelinating diseases: 《World Journal of Clinical Cases》2024年第30期6361-6373,共13页Robert Medina Ann-Marie Derias Maria Lakdawala Skye Speakman Brandon Lucke-Wold; Robert Medina 0009-0004-1811-6105;Brandon Lucke-Wold,RCID number:0000-0001-6577-4080.; This paper provides an overview of autoimmune disorders of the central nervous system,specifically those caused by demyelination.We explore new research regarding potential therapeutic interventions,particularly those...; 关键词：Central nervous system disease AUTOIMMUNE REMYELINATION DEMYELINATION MYELIN OLIGODENDROCYTE Emerging therapies Multiple Sclerosis

MFG-E8 Alleviates Cognitive Impairments Induced by Chronic Cerebral Hypoperfusion by Phagocytosing Myelin Debris and Promoting Remyelination被引量：2: 《Neuroscience Bulletin》2024年第4期483-499,共17页Xiaohong Dong Zhi Zhang Xin Shu Zi Zhuang Pinyi Liu Renyuan Liu Shengnan Xia Xinyu Bao Yun Xu Yan Chen; supported by the National Natural Science Foundation of China(81801147 and 81971112).; Chronic cerebral hypoperfusion is one of the pathophysiological mechanisms contributing to cognitive decline by causing white matter injury.Microglia phagocytosing myelin debris in a timely manner can promote remyelin...; 关键词：White matter injury Cognitive dysfunction MFG-E8 REMYELINATION Microglial phagocytosis

Star power: harnessing the reactive astrocyte response to promote remyelination in multiple sclerosis: 《Neural Regeneration Research》2024年第3期578-582,共5页Markley Silva Oliveira Junior Laura Reiche Emerson Daniele Ines Kortebi Maryam Faiz Patrick Küry; supported by the Heart and Stroke Foundation and Ontario Institute of Regenerative Medicine (New Ideas Grant);Canada First Research Excellence Fund(Medicine by Design);the National Sciences and Engineering Research Council;the Jurgen Manchot Foundation;the Christiane and Claudia Hempel Foundation for Clinical Stem Cell Research and the James and Elisabeth Cloppenburg,Peek and Cloppenburg Düsseldorf Stiftung (to PK); Astrocytes are indispensable for central nervous system development and homeostasis.In response to injury and disease,astrocytes are integral to the immunological-and the,albeit limited,repair response.In this review,...; 关键词：ASTROCYTES DEMYELINATION drug-based therapies myelin repair oligodendrocyte precursor cells reactive astrogliosis

Novel insights in phosphodiesterase 4 subtype inhibition to target neuroinflammation and stimulate remyelination: 《Neural Regeneration Research》2024年第3期493-494,共2页Melissa Schepers Tim Vanmierlo; In neurodegenerative and classically demyelinating disorders such as multiple sclerosis(MS),spinal cord injury(SCI),stroke,and Charcot-Marie-Tooth disease,glial functioning is compromised and nervous tissue integrity ...; 关键词：IMPAIRED INFLAMMATION Marie

The aminosteroid U73122 promotes oligodendrocytes generation and myelin formation: 《Acta Pharmacologica Sinica》2024年第3期490-501,共12页Shi-hao Cui Na Suo Ying Yang Xuan Wu Shi-meng Guo Xin Xie; supported by grants from the Ministry of Science and Technology of China(STI2030 Major Projects 2022ZD0204700);the National Natural Science Foundation of China(82121005,82003723,82330113).; Oligodendrocytes(OLs)are glial cells that ensheath neuronal axons and form myelin in the central nervous system(CNS).OLs are differentiated from oligodendrocyte precursor cells(OPCs)during development and myelin repai...; 关键词：OLIGODENDROCYTE oligodendrocyte progenitor cell DIFFERENTIATION REMYELINATION U73122

Activation of glutamatergic neurons in the somatosensory cortex promotes remyelination in ischemic vascular dementia: 《Fundamental Research》2024年第1期188-198,共11页Yi-Ting Zhou Da-Dao An Yi-Xin Xu Ying Zhou Qing-Qing Li Hai-Bin Dai Xiang-Nan Zhang Yi Wang Min Lou Zhong Chen Wei-Wei Hu; We would like to thank the Core Facilities,Zhejiang University School of Medicine for technical support.This work was supported by the National Natural Science Foundation of China(81973302,81903580);the National Key R&D Program of China(2020YFA0803900);the Zhejiang Provincial Natural Science Foundation of China(LR17H310001,LYY22H310003).; Chronic cerebral hypoperfusion can cause progressive demyelination as well as ischemic vascular dementia,however no effective treatments are available.Here,based on magnetic resonance imaging studies of patients with ...; 关键词：Chronic cerebral hypoperfusion Optogenetic stimulation Oligodendrocyte progenitor cellIschemic vascular dementia Glutamatergic neuron REMYELINATION

高级检索 检索式检索

时间限定

期刊范围

学科限定全选

高级检索 检索式检索

时间限定

期刊范围

学科限定全选

REMYELINATION

检索结果分析

下载全文

高级检索检索式检索

时间限定

期刊范围

学科限定全选

高级检索 检索式检索

时间限定

期刊范围

学科限定全选

REMYELINATION

检索结果分析

下载全文

用户登录

高级检索检索式检索