AUTOIMMUNE

作品数:462被引量:1664H指数:18
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相关领域:医药卫生更多>>
相关作者:廉哲雄梁艳姚远邱德凯马雄更多>>
相关机构:中华医学会复旦大学吉林大学白求恩第一医院第二军医大学更多>>
相关期刊:更多>>
相关基金:国家自然科学基金中国博士后科学基金北京市自然科学基金广东省自然科学基金更多>>
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Role of autoimmune phenomena in nonalcoholic fatty liver disease:Insights and limitations
《World Journal of Hepatology》2025年第3期229-232,共4页Arunkumar Krishnan Diptasree Mukherjee 
Metabolic dysfunction-associated steatotic liver disease,previously known as nonalcoholic fatty liver disease(NAFLD),is becoming increasingly common and is associated with significant morbidity and mortality related t...
关键词:Nonalcoholic fatty liver disease Metabolic dysfunction-associated steatotic liver disease Liver Regression Liver pathology AUTOANTIBODY AUTOIMMUNE 
Fourth-generation chimeric antigen receptor T-cell therapy is tolerable and efficacious in treatment-resistant rheumatoid arthritis
《Cell Research》2025年第3期220-223,共4页Yujing Li Sujun Li Xiaojuan Zhao Jun Sheng Lei Xue Georg Schett Ce Shi Biliang Hu Xingbing Wang Zhu Chen 
supported by the National Natural Science Foundation of China(82471819 and 81871227 to Z.C.);Anhui Provincial Health Research Foundation(AHWJ2023A10120 to Z.C.);Anhui Provincial Natural Science Foundation(2408085J046 to Z.C.);Anhui Provincial Key Research and Development Plan(2022h11020009 to Z.C.);the Fundamental Research Funds for the Central Universities(YD9110002012 to Z.C.).
Dear Editor,Rheumatoid arthritis(RA)is an autoimmune inflammatory disease characterized by symmetric synovial inflammation leading to progressive disability.1 Treatment of RA has been revolutionized by the development...
关键词:chimeric antigen receptor autoimmune inflammatory disease fourth generation t cell therapy treatment resistant tolerable rheumatoid arthritis symmetric synovial inflammation 
Mortality-related health metrics in systemic autoimmune diseases:an epidemiological analysis of a nationwide register-based cohort
《Science Bulletin》2025年第4期492-495,共4页Mucong Li Chanyuan Wu Peng Yin Junyan Qian Jiuliang Zhao Qian Wang Dong Xu Jinmei Su Xiaomei Leng Wenjie Zheng Xinping Tian Yan Zhao AlíDuarte-García Mengtao Li Xiaofeng Zeng Maigeng Zhou 
supported by the Chinese National Key Technology Research and Development Program,Ministry of Science and Technology(2022YFC2504600,2021YFC2501300 and 2019YFC0840603);Beijing Municipal Science&Technology Commission(Z201100005520022,23,25-27);CAMS Innovation Fund for Medical Sciences(CIFMS)(2021-I2M-1-005 and 2022-I2M-1-004);National High Level Hospital Clinical Research Funding(2022-PUMCH-A-107,B-013,C-002,D-009).
Systemic autoimmune diseases(sAIDs)are a spectrum of diseases with multi-organ involvement that share similar clinical manifestations[1].The capacity for diagnosis and treatment of sAIDs is closely associated with the...
关键词:diseases AUTOIMMUNE INVOLVEMENT 
Advances and challenges in diagnosing and managing adult autoimmune enteropathy
《World Journal of Gastroenterology》2025年第2期128-131,共4页Grigorios Christodoulidis Sara E Agko Marina N Kouliou Konstantinos E Koumarelas Dimitris Zacharoulis 
Autoimmune enteropathy(AIE)is a rare immune mediated disorder primarily affecting children,characterized by chronic diarrhea,malabsorption,vomiting,weight loss and villous atrophy.It has also been observed in adults p...
关键词:Autoimmune enteropathy Diagnosis Prognosis Adult autoimmune enter-opathy and challenges Autoimmune enteropathy and treatment Autoimmune enteropathy and diagnostic criteria Pathophysiology of autoimmune enteropathy 
Evaluation of autoimmune phenomena in patients with nonalcoholic fatty liver disease on the basis of liver pathology被引量:1
《World Journal of Hepatology》2024年第12期1407-1416,共10页Yu-Jin Zhu Yan Zhang Yao Rao Yong Jiang Yong-Gang Liu Jian-Zhou Li Jia-Qi Yuan Ying Zhao Wen-Wen Zheng Lin Ma Chun-Yan Wang Jia Li 
BACKGROUND Autoimmune phenomena can be used in some patients with nonalcoholic fatty liver disease(NAFLD)in the clinic,but these patients are not autoimmune hepatitis patients.AIM To determine whether autoimmunity is ...
关键词:Nonalcoholic fatty liver disease Liver pathology AUTOANTIBODY AUTOIMMUNITY Clinical indicator 
Bailing capsule(百令胶囊)alleviates autoimmune thyroiditis via regulating peroxisome proliferator-activated receptor signaling pathway:a multi-omics analysis
《Journal of Traditional Chinese Medicine》2024年第6期1217-1226,共10页WANG Qixin XU Liting WU Jiangpeng HE Xueling TANG Huan CHENG Guangqing LU Tianming DAI Chuanhao GUO Qiuyan WANG Jigang 
Innovation Team and Talents Cultivation Program of National Administration of Traditional Chinese Medicine:Studies on the Antimalarial and Drug Resistance Mechanisms of Artemisinin and the Expansion of New Indications (No. ZYYCXTD-C-202002)。
OBJECTIVE: To investigate the efficacy and potential mechanism of Bailing capsule( 百令胶囊, BL) antiautoimmune thyroiditis(AIT). METHODS: Based on the AIT rat model, the effect of BL in alleviating AIT was evaluated ...
关键词:THYROIDITIS AUTOIMMUNE CORDYCEPS fatty acid peroxisome proliferator-activated receptors Bailing capsule 
Primary Raynaud’s Syndrome: An Intrinsic Autoimmune Disease that Is Amenable to Mycophenolate Mofetil
《Case Reports in Clinical Medicine》2024年第11期485-489,共5页Kamel El-Reshaid Shaima Al-Bader 
Raynaud’s syndrome (RS) is a vasospastic disorder with potential hereditary predisposition and multiple triggering factors. After the exclusion of external stimuli and local disorders, autoimmunity presents a potenti...
关键词:Raynaud’s Syndrome Mycophenolate Mofetil Treatment AUTOIMMUNE IDIOPATHIC 
Neuronal trafficking as a key to functional recovery in immune-mediated neuropathies
《Neural Regeneration Research》2024年第11期2331-2332,共2页Felix Kohle Michael Schroeter 
supported by the Deutsche Forschungsgemeinschaft(DFG,German Research Foundation):project ID 431549029-SFB 1451(to MS).
Immune-mediated neuropathies are rare diseases of the peripheral nervous system(PNS),substantially affecting patients’functionality and quality of life.They are amenable to immunomodulatory treatments,which in many c...
关键词:DISEASES AUTOIMMUNE 
Type 17 immunity:novel insights into intestinal homeostasis and autoimmune pathogenesis driven by gut-primed T cells
《Cellular & Molecular Immunology》2024年第11期1183-1200,共18页Daiya Ohara Yusuke Takeuchi Keiji Hirota 
supported by JSPS grants-in-aid for Scientific Research(22J20213 to DO and 19H01026 to KH);the Cooperative Research Program(Joint Usage/Research Center program)of the Institute for Life and Medical Sciences,Kyoto University(KH).Figures 1,3,4,and 5 were created with Biorender.com.
The IL-23 signaling pathway in both innate and adaptive immune cells is vital for orchestrating type 17 immunity,which is marked by the secretion of signature cytokines such as IL-17,IL-22,and GM-CSF.These proinflamma...
关键词:IL-23 Th17 cDCIL-23 Inflammatory bowel diseases(IBD) Gut-joint axis Gut-brain axis 
Miniproteins may have a big impact:new therapeutics for autoimmune diseases and beyond
《Signal Transduction and Targeted Therapy》2024年第11期4785-4787,共3页Nariaki Asada Christian F.Krebs Ulf Panzer 
supported by grants from the Deutsche Forschungsgemeinschaft(DFG)to U.P.(SFB 1192 A1 and C3);C.F.K.(SFB 1192 A5 and C3,KR 3483/3-1).
In a landmark study recently published in Cell,Berger et al.demonstrated that computationally designed miniproteins could serve as novel,orally available treatment strategies by specifically targeting cytokine signali...
关键词:AUTOIMMUNE DISEASES 
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