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作品数：809被引量：1819H指数：17
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Small heat shock protein B8:from cell functions to its involvement in diseases and potential therapeutic applications被引量：1
《Neural Regeneration Research》2025年第10期2872-2886,共15页Marta Chierichetti Riccardo Cristofani Valeria Crippa Veronica Ferrari Marta Cozzi Elena Casarotto Paola Pramaggiore Laura Cornaggia Guglielmo Patelli Ali Mohamed Margherita Piccolella Mariarita Galbiati Paola Rusmini Barbara Tedesco Angelo Poletti 
supported by:Fondazione Telethon-Italy(No.GGP19128 to AP);Fondazione Cariplo-Italy(No.2021-1544 to RC);Fondazione Italiana di Ricerca per la Sclerosi Laterale Amiotrofica(AriSLA)-Italy(No.MLOpathy to AP;Target-RAN to AP);Association Française contre les Myopathies-France(AFM Telethon No.23236 to AP);Kennedy’s Disease Association-USA(2018 grant to RC;2020 grant to MG);Ministero dell’Universitàe della Ricerca(MIUR)-Italy(PRIN-Progetti di ricerca di interesse nazionale(No.2017F2A2C5 to AP;No.2022EFLFL8 to AP;No.2020PBS5MJ to VC;No.2022KSJZF5 to VC);PRIN-Progetti di ricerca di interesse nazionale-bando 2022,PNRR finanziato dall’Unione europea-Next Generation EU,componente M4C2,investimento 1.1(No.P2022B5J32 to RC and No.P20225R4Y5 to VC);CN3:RNA-Codice Proposta:CN_00000041;Tematica Sviluppo di terapia genica e farmaci con tecnologia a RNA(Centro Nazionale di Ricerca-CN3 National Center for Gene Therapy and Drugs based on RNA Technology to AP);Progetto Dipartimenti di Eccellenza(to DiSFeB);Ministero della Salute,Agenzia Italiana del Farmaco(AIFA)-Italy(Co_ALS to AP);Universitàdegli Studi di Milano(piano di sviluppo della ricerca(PSR)UNIMI-linea B(to RC and BT).
Heat shock protein family B(small)member 8(HSPB8)is a 22 kDa ubiquitously expressed protein belonging to the family of small heat shock proteins.HSPB8 is involved in various cellular mechanisms mainly related to prote...
关键词：AGGREGATION AUTOPHAGY cancer CHAPERONE chaperone-assisted selective autophagy cognitive impairment HSPB8 NEUROINFLAMMATION neuromuscular diseases therapy 
Glucocorticoid receptor signaling in the brain and its involvement in cognitive function
《Neural Regeneration Research》2025年第9期2520-2537,共18页Chonglin Su Taiqi Huang Meiyu Zhang Yanyu Zhang Yan Zeng Xingxing Chen 
supported by the National Natural Science Foundation of China,No.82371444(to YZ);the Natural Science Foundation of Hubei Province,No.2022CFB216(to XC);the Key Research Project of Ministry of Science and Technology of China,No.2022ZD021160(to YZ)。
The hypothalamic-pituitary-adrenal axis regulates the secretion of glucoco rticoids in response to environmental challenges.In the brain,a nuclear receptor transcription fa ctor,the glucocorticoid recepto r,is an impo...
关键词：brain-derived neurotrophic factor calcium signaling glucocorticoid receptor GLUCOCORTICOID glutamate transmission hypothalamic-pituitary-adrenal axis long-term potentiation neurocognitive disorders NEUROPLASTICITY stress 
Abdominal tuberculosis with pancreatic head involvement mimicking pancreatic malignancy in a young man:A case report
《World Journal of Clinical Cases》2025年第18期46-52,共7页Lei Ma Kun-Peng Wang Chong Jin 
BACKGROUND Pancreatic tuberculosis(PTB)is a rare disease,even in immunocompetent hosts.Abdominal tuberculosis involving the pancreatic head and peripancreatic areas may simulate pancreatic head carcinoma.CASE SUMMARY ...
关键词：Pancreatic tuberculosis Pancreatic head carcinoma Computed tomography LAPAROTOMY Case report 
Unexpected contralateral axillary lymph node metastasis without ipsilateral involvement in triple-negative breast cancer:A case report and review of literature
《World Journal of Clinical Cases》2025年第18期85-93,共9页Yun-Ting Lin Zhi-Jie Hong Guo-Shiou Liao Ming-Shen Dai Tai-Kuang Chao Wen-Chiuan Tsai Yu-Kai Sung Chuang-Hsin Chiu Cheng-Kuang Chang Jyh-Cherng Yu 
BACKGROUND Breast cancer is a leading cause of cancer-related mortality among women worldwide,with invasive ductal carcinoma(IDC)being the most prevalent subtype.Lymph node metastasis is the primary prognostic indicat...
关键词：Triple negative breast neoplasms Invasive ductal carcinoma Lymphatic metastasis Contralateral axillary metastasis Positron-emission tomography Case report 
Between Culture and Solidarity
《ChinAfrica》2025年第5期52-54,共3页LI XIAOYU 
An African student in Hangzhou is furthering the cause of intercultural dialogue through community involvement.During the 19th Asian Games held in east China’s Hangzhou,McCleary Gondo,a 27-year-old Zimbabwean student...
关键词：community involvementduring Asian Games CULTURE community involvement intercultural dialogue SOLIDARITY Hangzhou 
The burden of upper motor neuron involvement is correlated with the bilateral limb involvement interval in patients with amyotrophic lateral sclerosis:a retrospective observational study
《Neural Regeneration Research》2025年第5期1505-1512,共8页Jieying Wu Shan Ye Xiangyi Liu Yingsheng Xu Dongsheng Fan 
supported by the National Natural Science Foundation of China,Nos.82071426,81873784;Clinical Cohort Construction Program of Peking University Third Hospital,No.BYSYDL2019002(all to DF)。
Amyotrophic lateral sclerosis is a rare neurodegenerative disease characterized by the involvement of both upper and lower motor neurons.Early bilateral limb involvement significantly affects patients'daily lives and ...
关键词：amyotrophic lateral sclerosis bilateral limb involvement Cox proportional hazards regression model horizontal spread restricted cubic spline analysis time interval upper motor neuron vertical spread 
Discrepant involvement of homologous repair and non-homologous end joining pathways in maize development and growth
《The Crop Journal》2025年第2期406-417,共12页Shuanghui Zhao Leiming Zheng Minghui Zheng Menghan Li Shuyue Li Nan Wu Yan He Jinghan Liu 
supported by the National Natural Science Foundation of China(32372116)to Yan He.
Chromosomal DNA double-strand breaks(DSBs)are often generated in the genome of all living organisms.To combat DNA damage,organisms have evolved several DSB repair mechanisms,with nonhomologous end-joining(NHEJ)and hom...
关键词：Homologous recombination Non-homologous end joining Double-strand break MAIZE 
Involvement of bacteria in the development of fungal infections in the Colorado potato beetle
《Insect Science》2025年第2期600-620,共21页Vadim Yu.Kryukov Elena Kosman Irina Slepneva Yana L.Vorontsova Olga Polenogova Gleb Kazymov Tatyana Alikina Yuriy Akhanaev Darya Sidorenko Yury A.Noskov Anton Krivopalov Marsel R.Kabilov Olga Yaroslavtseva 
support from the Russian Science Foundation(No.20-74-10043);continued with the same funding(No.22-14-00309).
Entomopathogenic fungi may interact with insects’symbiotic bacteria during infection.We hypothesized that topical infection with Beauveria bassiana may alter the microbiota of the Colorado potato beetle(CPB)and that ...
关键词：Beauveria bassiana GUT IMD INTEGUMENT JAK-STAT MICROBIOTA 
Genome-wide analysis of the NF-Y gene family in non-heading Chinese cabbage and the involvement of Bc NF-YA8 in ABA-mediated flowering regulation
《Horticultural Plant Journal》2025年第2期661-679,共19页Yan Li Yu Tao Aimei Bai Haibin Wang Zhanghong Yu Tongkun Liu Xilin Hou Ying Li 
supported by the National Natural Science Foundation of China(Grant No.31872106);the National Vegetable Industry Technology System(Grant No.CARS-23-A-16);the Jiangsu Seed Industry Revitalization Project(Grant No.JBGS(2021)015);the Priority Academic Program Development of Jiangsu Higher Education Institutions。
The nuclear factor Y(NF-Y)is a class of heterotrimeric transcription factors comprising three subunits:NF-YA,NF-YB,and NF-YC.These transcription factors participate in many plant bioprocesses,including the regulation ...
关键词：Non-heading Chinese cabbage Nuclear factor Y Genome-wide analysis ABA FLOWER 
Involvement of the ubiquitin-proteasome system in the regulation of the tumor microenvironment and progression
《Genes & Diseases》2025年第2期227-243,共17页Yulan Huangg Yuan Gao Zhenghong Lin Hongming Miao 
supported in part by the National Natural Science Foundation of China (No.82173134);the Chongqing Fund for Outstanding Youth (China) (No.CSTB2022NSCO-JOX0010).
The tumor microenvironment is a complex environment comprising tumor cells,non-tumor cells,and other critical non-cellular components.Some studies about tumor micro-environment have recently achieved remarkable progre...
关键词：Adipose cells DEUBIQUITINATION IMMUNITY Tumor microenvironment Tumor-associated fibroblasts UBIQUITINATION 
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