GUT

作品数:1077被引量:4872H指数:31
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相关领域:医药卫生更多>>
相关作者:于天枢成惠林齐猛王汉东杭春华更多>>
相关机构:上海交通大学河海大学浙江工商大学上海先惠自动化技术股份有限公司更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划中国博士后科学基金高等学校学科创新引智计划更多>>
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Gut–brain axis and environmental factors in Parkinson's disease:bidirectional link between disease onset and progression
《Neural Regeneration Research》2025年第12期3416-3429,共14页Soo Jung Park Kyung Won Kim Eun Jeong Lee 
supported by the National Research Foundation(NRF)of Korea(2022R1C1C1005741 and RS-2023-00217595)。
Parkinson's disease has long been considered a disorder that primarily affects the brain,as it is defined by the dopaminergic neurodegeneration in the substantia nigra and the brain accumulation of Lewy bodies contain...
关键词:gut inflammation gut microbiome gut-brain axis micro/nano-plastics Parkinson’s disease Α-SYNUCLEIN 
The gut-eye axis:from brain neurodegenerative diseases to age-related macular degeneration
《Neural Regeneration Research》2025年第10期2741-2757,共17页Qianzi Jin Suyu Wang Yujia Yao Qin Jiang Keran Li 
supported by the National Natural Science Foundation of China,No.82171080;Nanjing Medical Science and Technology Development Project,No.YKK23264;Postgraduate Research&Practice Innovation Program of Jiangsu Province,Nos.JX10414151,JX10414152(all to KL)。
Age-related macular degeneration is a serious neurodegenerative disease of the retina that significantly impacts vision.Unfortunately,the specific pathogenesis remains unclear,and effective early treatment options are...
关键词:age-related macular degeneration biological agents blinding eye disease dietary nutrition fecal microbial transplantation gut-eye axis intestinal flora METABOLITE MICROECOLOGY neurodegenerative disease 
Interaction between gut virome and microbiota on inflammatory bowel disease
《World Journal of Methodology》2025年第3期17-21,共5页Xiao-Long Li Mueen Megdadi Humair S Quadri 
Inflammatory bowel disease(IBD),encompassing Crohn's disease and ulcerative colitis,is a chronic condition marked by recurring gastrointestinal inflammation.While immune,genetic,and environmental factors are well-stud...
关键词:Virome MICROBIOTA Inflammatory bowel disease LYSOGENY Horizontal gene transfer 
Gut virome and its emerging role in inflammatory bowel disease
《World Journal of Methodology》2025年第3期22-24,共3页Rahat Khatoon Khokhar Abdulqadir J Nashwan 
Inflammatory bowel disease(IBD)is a progressive multifactorial inflammatory disease of the gut.The cause of IBD is yet unknown.Some researchers have shown that genetic factors,environmental factors,and the gut microbi...
关键词:Inflammatory bowel disease PATHOGENESIS Gut virome BACTERIOPHAGE Eukaryotic viruses 
Bidirectional regulation of the brain-gut-microbiota axis following traumatic brain injury被引量:1
《Neural Regeneration Research》2025年第8期2153-2168,共16页Xinyu You Lin Niu Jiafeng Fu Shining Ge Jiangwei Shi Yanjun Zhang Pengwei Zhuang 
supported by the National Natural Science Foundation of China,No.82174112(to PZ);Science and Technology Project of Haihe Laboratory of Modern Chinese Medicine,No.22HHZYSS00015(to PZ);State-Sponsored Postdoctoral Researcher Program,No.GZC20231925(to LN)。
Traumatic brain injury is a prevalent disorder of the central nervous system.In addition to primary brain parenchymal damage,the enduring biological consequences of traumatic brain injury pose long-term risks for pati...
关键词:traumatic brain injury brain-gut-microbiome axis gut microbiota NEUROIMMUNE immunosuppression host defense vagal afferents bacterial infection dorsal root ganglia nociception neural circuitry 
Calycosin improves atherosclerosis by reshaping the interaction between the gut microbiome and bile acid metabolism
《Food Science and Human Wellness》2025年第4期1369-1386,共18页Jiaqi Fu Donghua Yu Yuqin Liang Xin Gao Yunhe Shi Yu Wang Pingping Chen Fang Lu Shumin Liu 
supported by Heilongjiang Postdoctoral Program(ZHY2022-114);General program of Heilongjiang Province(LBHZ22251);Young Elite Scientists Sponsorship Program(2022-QNRC1-27)。
Calycosin,Astragali Radix most prominent ingredient,has drawn more attention as a result of its ability to treat atherosclerosis(AS).However,the mechanism of action has not been fully elucidated.We investigated the ef...
关键词:CALYCOSIN Atherosderosis Bile acid metabolism Gut microbiota 
Nootkatone suppresses TLR4/NF-κB/NLRP3 pathway to alleviate non-alcoholic fatty liver disease via modulating gut microbiota
《Food Science and Human Wellness》2025年第4期1398-1410,共13页Rongrong Fu Wenqing Xue Jingjie Liang Lechen Wang Min Zhang Jing Meng 
supported by grants from National Natural Science Foundation of China(82072709,81902441);Natural Science Foundation of Tianjin Municipal(23JCYBJC00850);China Postdoctoral Science Foundation(2022M712374);Tianjin“131”Innovative Talent Team Project(201926)。
Non-alcoholic fatty liver disease(NAFLD)is one of the most common chronic liver diseases worldwide.Gut microbiota and its metabolites alteration are closely related to NAFLD.Nootkatone is an edible flavorant derived f...
关键词:Nootkatone Non-alcoholic fatty liver disease Hepatic inflammation TLR4/NF-κB/NLRP3 Gut microbiome 
Inhibition of the cGAS–STING pathway:contributing to the treatment of cerebral ischemia-reperfusion injury
《Neural Regeneration Research》2025年第7期1900-1918,共19页Hang Yang Yulei Xia Yue Ma Mingtong Gao Shuai Hou Shanshan Xu Yanqiang Wang 
supported by Yuan Du Scholars,Clinical Research Center of Affiliated Hospital of Shandong Second Medical University,No.2022WYFYLCYJ02;Weifang Key Laboratory,Weifang Science and Technology Development Plan Project Medical Category,No.2022YX093.
The cGAS–STING pathway plays an important role in ischemia-reperfusion injury in the heart,liver,brain,and kidney,but its role and mechanisms in cerebral ischemia-reperfusion injury have not been systematically revie...
关键词:calcium homeostasis cellular autophagy cerebral ischemia-reperfusion injury cGAS–STING pathway ferroptosis gut–brain–microbiota axis inflammatory light chain 3 microglial cells Syntaxin-17 protein 
Breaking the cycle:Psychological and social dimensions of pediatric functional gastrointestinal disorders
《World Journal of Clinical Pediatrics》2025年第2期137-175,共39页Mohammed Al-Beltagi Nermin K Saeed Adel S Bediwy Reem Elbeltagi 
BACKGROUND Functional gastrointestinal disorders(FGIDs)in children present with chronic symptoms like abdominal pain,diarrhea,and constipation without identifiable structural abnormalities.These disorders are closely ...
关键词:Functional gastrointestinal disorders Psychiatric comorbidities Gut-brain axis Pediatric mental health Psychosocial stress 
Integrative review of the gut microbiome’s role in pain management for orthopaedic conditions
《World Journal of Experimental Medicine》2025年第2期40-50,共11页Naveen Jeyaraman Madhan Jeyaraman Priya Dhanpal Swaminathan Ramasubramanian Arulkumar Nallakumarasamy Sathish Muthu Gabriel Silva Santos Lucas Furtado da Fonseca JoséFábio Lana 
The gut microbiome,a complex ecosystem of microorganisms,has a significant role in modulating pain,particularly within orthopaedic conditions.Its impact on immune and neurological functions is underscored by the gut-b...
关键词:Gut microbiome Pain management ORTHOPAEDICS Gut-brain axis PROBIOTICS Inflammation 
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