OLIGODENDROCYTES

作品数：67被引量：224H指数：7
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相关领域：医药卫生生物学更多>>
相关作者：蒋晓燕徐晓明胡建国马睿杰金建强更多>>
相关机构：杭州师范大学德克萨斯大学浙江中医药大学中国药科大学更多>>
相关期刊：《Open Journal of Medical Psychology》《Life Metabolism》《Zoological Research》《Chinese Journal of Traumatology》更多>>
相关基金：国家自然科学基金北京市自然科学基金国家重点基础研究发展计划重庆市自然科学基金更多>>
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Zebrafish optic nerve regeneration involves resident and retinal oligodendrocytes
《Neural Regeneration Research》2026年第2期811-820,共10页Cristina Pérez-Montes Rosalía Hernández-García Jhoana Paola Jiménez-Cubides Laura DeOliveira-Mello Almudena Velasco Rosario Arévalo Marina García-Macia Adrián Santos-Ledo 
supported by the Lanzadera TCUE and C2 program(Universidad de Salamanca)(to ASL);the Spanish National Research Council(CSIC)funded by the Junta de Castilla y León and co-financed by the European Regional Development Fund(ERDF“Europe drives our growth)”:Internationalization Project“CL-EI-2021-08-IBFG Unit of Excellence”,Grant(PID2022-138478OA-100)funded by MICIU/AEI/10.13039/501100011033 and,by FEDER,UE(to MGM);Junta de Castilla y León(SA225P23)and Gerencia Regional de Salud(2701/A1/2023)(to AV);the Plan Especial Grado Medicina(USAL)(to CPM);a Ramón y Cajal researcher:Grant RYC2021-033684-I funded by MICIU/AEI/10.13039/501100011033 and,by European Union NextGenerationEU/PRTR.
The visual system of teleost fish grows continuously,which is a useful model for studying regeneration of the central nervous system.Glial cells are key for this process,but their contribution is still not well define...
关键词：cell death OLIGODENDROCYTES optic nerve proliferation regeneration Sox10 SOX2 visual system ZEBRAFISH 
Oligodendroglial heterogeneity in health,disease,and recovery:deeper insights into myelin dynamics
《Neural Regeneration Research》2025年第11期3179-3192,共14页Pieter-Jan Serneels Julie D.De Schutter Lies De Groef Lieve Moons Steven Bergmans 
supported by KU Leuven Internal Funding(C3/21/012);the Research Foundation Flanders(FWO G092222N)(to LM)。
Decades of research asserted that the oligodendroglial lineage comprises two cell types:oligodendrocyte precursor cells and oligodendrocytes.However,recent studies employing single-cell RNA sequencing techniques have ...
关键词：animal models DEMYELINATION fish MAMMALS multiple sclerosis MYELIN neurodegeneration OLIGODENDROCYTES oligodendroglial lineage REMYELINATION 
Heterogeneity of mature oligodendrocytes in the central nervous system
《Neural Regeneration Research》2025年第5期1336-1349,共14页Chao Weng Adam M.R.Groh Moein Yaqubi Qiao-Ling Cui Jo Anne Stratton G.R.Wayne Moore Jack P.Antel 
supported by a grant from the Progressive MS Alliance(BRAVE in MS);Le Grand Portage Fund。
Mature oligodendrocytes form myelin sheaths that are crucial for the insulation of axons and efficient signal transmission in the central nervous system.Recent evidence has challenged the classical view of the functio...
关键词：aging central nervous system diseases electron microscopy HETEROGENEITY immunohistochemistry myelin sheath natural history NEUROGLIA OLIGODENDROGLIA single-cell gene expression analysis 
Autophagy in Oligodendrocyte Lineage Cells Controls Oligodendrocyte Numbers and Myelin Integrity in an Age‑dependent Manner
《Neuroscience Bulletin》2025年第3期374-390,共17页Hong Chen Gang Yang De‑En Xu Yu‑tong Du Chao Zhu Hua Hu Li Luo Lei Feng Wenhui Huang Yan‑Yun Sun Quan‑Hong Ma 
supported by the STI2030-Major Projects(2021ZD0204001);the National Natural Science Foundation of China(92049120,81870897,81271424,81671111,and 62475179);the Sino German Cooperation and Exchange Project(M-0679);the Guangdong Key Project in the Development of New Tools for the Diagnosis and Treatment of Autism(2018B030335001);the Natural Science Foundation of Jiangsu Province(BK20181436);the Priority Academic Program Development of Jiangsu Higher Education Institutions,the Jiangsu Key Laboratory of Translational Research and Therapy for Neuro-Psycho-Diseases(BM2013003);Suzhou International Joint Laboratory for Diagnosis and Treatment of Brain Diseases,Suzhou Science and Technology Plan Medical and Health Care Science and Technology Innovation Applied Basic Research(SKY2022161);the Research Project of Neurological Diseases in the Second Affiliated Hospital of Soochow University Research Center(ND2023A01);Boxi clinical research project of The First Affiliated Hospital of Soochow University(BXQN202204);Suzhou Science&Technology Projects for People's Livelihood(SKY2021065);Wuxi Municipal Health Commission(M202204).
Oligodendrocyte lineage cells, including oligodendrocyte precursor cells (OPCs) and oligodendrocytes (OLs), are essential in establishing and maintaining brain circuits. Autophagy is a conserved process that keeps the...
关键词：AUTOPHAGY Oligodendrocyte precursor cells OLIGODENDROCYTES MYELINATION Myelin proteins Turnover Degradation 
Oligodendrocytes in central nervous system diseases:the effect of cytokine regulation被引量：2
《Neural Regeneration Research》2024年第10期2132-2143,共12页Chengfu Zhang Mengsheng Qiu Hui Fu 
supported by the Natural Science Foundation of Zhejiang Province,No.LQ23C090003 (to CZ);the Major Project on Brain Science and Analog Brain Research of Ministry of Science and Technology of China,No.2022ZD0204701 (to MQ);the National Natural Science Foundation of China,No.32170969 (to MQ)。
Cytokines including tumor necrosis factor, interleukins, interferons, and chemokines are abundantly produced in various diseases. As pleiotropic factors, cytokines are involved in nearly every aspect of cellular funct...
关键词：ASTROCYTE central nervous system disease CXC chemokine cytokine interferonγ INTERLEUKIN MICROGLIA OLIGODENDROCYTE oligodendrocyte precursor cell tumor necrosis factorα 
Inhibition of YIPF2 Improves the Vulnerability of Oligodendrocytes to Human Islet Amyloid Polypeptide
《Neuroscience Bulletin》2024年第10期1403-1420,共18页Nan Zhang Xiaoying Ma Xinyu He Yaxin Zhang Xin Guo Zhiyuan Shen Xiaosu Guo Danshen Zhang Shujuan Tian Xiaowei Ma Yuan Xing 
supported by the National Natural Science Foundation of China (82100863);Hebei Natural Science Foundation (H2020206643 and H2020206105);Funding project for introducing overseas students of Hebei Province (C20210346);Medical Science Research Project of Hebei Province (20211628);Hebei Province Government-funded Excellent Talents Project in Clinical Medicine (ZF2023029);Spark Scientific Research Project of the First Hospital of Hebei Medical University (XH202004).
Excessive secretion of human islet amyloid polypeptide(hIAPP)is an important pathological basis of diabetic encephalopathy(DE).In this study,we aimed to investigate the potential implications of hIAPP in DE pathogenes...
关键词：Diabetic encephalopathy Human islet amyloid polypeptide Oligodendrocytes:Yeast Rab GTPase-interacting protein 2-Monocarboxylate transporters CD147 
Abnormal expression of Tau in damaged oligodendrocytes of HLD1 mice
《Neural Regeneration Research》2024年第7期1405-1406,共2页Tomohiro Torii 
Patients with hypomyelinating leukodystrophies(H LDs),multiple sclerosis(MS),and leukodystrophies including Aicardi-Goutieres syndrome,adrenoleukodystrophy,Alexander disease,Canavan disease,cerebrotendinous xanthomato...
关键词：DYSTROPHY cytes Patients 
General anesthetic agents induce neurotoxicity through oligodendrocytes in the developing brain被引量：1
《Zoological Research》2024年第3期691-703,共13页Wen-Xin Hang Yan-Chang Yang Yu-Han Hu Fu-Quan Fang Lang Wang Xing-Hua Qian Patrick M.McQuillan Hui Xiong Jian-Hang Leng Zhi-Yong Hu 
supported by the Natural Science Foundation of Zhejiang Province(LZ22H090002,2014C33170);National Natural Science Foundation of China(82171260,81641042,81471240)。
General anesthetic agents can impact brain function through interactions with neurons and their effects on glial cells.Oligodendrocytes perform essential roles in the central nervous system,including myelin sheath for...
关键词：OLIGODENDROCYTES General anesthetic agents NEUROTOXICITY Central nervous system Perioperative neurocognitive disorders 
The Protective Effects of Flavonoids from Scutellaria Baicalensis Georgi Stems and Leaves on Oligodendrocyte Damage Induced by Aβ<sub>1-42</sub>
《Pharmacology & Pharmacy》2024年第1期1-13,共13页Tangtang Song Yinhui Yao Yazhen Shang 
Aim: This study aimed to investigate the protective effects of flavonoids from the stem and leaves of Scutellaria baicalensis Georgi (SSFs) against Aβ1-42-induced oligodendrocytes (OL) damage. Methods: Imm...
关键词：Flavonoids form the Stem and Leaves of Scutellaria baicalensis Georgi Aβ1-42 OLIGODENDROCYTES DAMAGE 
CDP-choline to promote remyelination in multiple sclerosis:the need for a clinical trial被引量：3
《Neural Regeneration Research》2023年第12期2599-2605,共7页Viktoria Gudi PawełGrieb Ralf ALinker Thomas Skripuletz 
Multiple sclerosis is a multifactorial chronic inflammatory disease of the central nervous system that leads to demyelination and neuronal cell death,resulting in functional disability.Remyelination is the natural rep...
关键词：ASTROCYTES CDP-CHOLINE CUPRIZONE microglia multiple sclerosis OLIGODENDROCYTES 
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