supported by a grant from the Progressive MS Alliance(BRAVE in MS);Le Grand Portage Fund。
Mature oligodendrocytes form myelin sheaths that are crucial for the insulation of axons and efficient signal transmission in the central nervous system.Recent evidence has challenged the classical view of the functio...
This paper is a systematic review of the treatment of bipolar disorder: a systematic Google Scholar search aimed at treatment guidelines and clinical trials. The search for treatment guidelines returned 375 papers and...
supported by the National Natural Science Foundation of China,No.81960242(to XLY);Yunnan Applied Basic Research Project of Yunnan Province of China,Nos.2019FE001-048(to XLY),202001AT070001(to XLY),“One Hundred Young and Middle-aged Academic and Technical Backbone”Training Program of Kunming Medical University,No.60118260105(to XLY);Miaozi Project in Science and Technology Innovation Program of Sichuan Province,No.2020JDRC0057(to HYH).
Inflammatory responses,including glial cell activation and peripheral immune cell infiltration,are involved in the pathogenesis of Parkinson’s disease(PD).These inflammatory responses appear to be closely related to ...
supported by EU Program FP7-PEOPLE-2013-IAPP(612218/3D-NET);FEDER-CICYT MAT2013-47501-CO2-1-R(Ministry of Economy and Competitiveness,Spain)Grants;supported by RETICS(RD12/0034/0001);Instituto de Salud CarlosⅢ,Spain
Diabetes mellitus is a leading cause of acquired vision loss and one of the world's fastest growing chronic diseases. Diabetic retinopathy (DR), a specific complication of chronic hyperglycemia, is the leading caus...
The proteolysis of the extracellular matrix plays a key role in the synaptic neuroplasticity of the central nervous system (CNS), which results in learning and memory. Proteases from the serine family and metalloprote...
supported by an Alzheimer’s Research Trust(UK)Programme Grant(ART/PG2004A/1)to A.V.;by a National Science Foundation grant(CBET 0943343)to V.P
Neuroglial cells are homeostatic neural cells. Generally, they are electrically non-excitable and their activation is associated with the generation of complex intracellular Ca^2+ signals that define the "Ca^2+ exc...
supported by a grant from the National Science and Technology Infrastructure Platform,Ministry of Science and Technology,No. 2005DKA32400
Most hypotheses concerning the mechanisms underlying Parkinson's disease are based on altered synaptic transmission of the nigrostriatal system. However, extrasynaptic transmission was recently found to affect dopami...
Authors research was supported by Alzheimer's Research Trust (UK) Programme Grant (ART/PG2004A/1) to AV; by National Institute of Health (NIH) grant to VP (R01 MH 069791); by National Science Foundation (CBET 0943343) grant to VP, by the Grant Agency of the Czech Republic (GACR 305/08/1381 and GACR 305/08/1384) to AV.
Our view of astrocytes in the operation of the brain is changing dramatically over the last 3 decades. Astroglial calcium excitability controls the release of gliotransmitters, which can occur at the tripartite synaps...
Spinal cord injuries are damages that result in complete or partial loss of sensation and/or mobility and affect the life qualities of many patients. Their pathophysiology in-cludes primary and secondary processes, wh...
the Scientific Research Foundation of the Higher Education Institutions, No. 20030183048
BACKGROUND: Cholinergic neuron directly participants in human motion, learning and memory and is a target cell for multiple degenerative diseases of central nervous system. OBJECTIVE: To investigate whether the mito...