云南高校图书馆联盟文献共享服务平台- FIBRONECTIN

FIBRONECTIN: 作品数：183被引量：388H指数：10; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：赵晓珍徐振晔陈其华李长青周跃更多>>; 相关机构：上海中医药大学重庆医科大学复旦大学湖南中医药大学更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划重庆市自然科学基金广东省自然科学基金更多>>

Therapeutic potential of exercise-hormone irisin in Alzheimer's disease: 《Neural Regeneration Research》2025年第6期1555-1564,共10页Eunhee Kim Rudolph ETanzi Se Hoon Choi; supported by Cure Alzheimer’s Fund (to RET and SHC);JPB Foundation (to RET),and R56AG072054 (to SHC)。; Irisin is a myokine that is generated by cleavage of the membrane protein fibronectin type Ⅲ domain-containing protein 5(FNDC5) in response to physical exercise. Studies reveal that irisin/FNDC5 has neuroprotective f...; 关键词：Alzheimer's disease EXERCISE fibronectin typeⅢdomain-containing protein 5(FNDC5) irisin

Cancer-associated fibroblasts derived fibronectin extra domain A promotes sorafenib resistance in hepatocellular carcinoma cells by activating SHMT1: 《Genes & Diseases》2024年第6期510-524,共15页Yan Dong Yanrong Chen Yijie Wang Xiang Zhao Ruiyang Zi Jie Hao Qiong Ding Haoran Jiang Xuesong Wang Fanghao Lu Houjie Liang Zhihao Wei Jianjun Li; supported in part by the National Natural Science Foundation of China (No.81672856,82203669,81803028);the General Program of Chongqing Natural Science Foundation (China) (No.cstc2021jcyj-msxmX0687).; Resistance to sorafenib,an effective first-line treatment for advanced hepatocellular carcinoma(HCC),greatly compromised the prognosis of patients.The extracellular matrix is one of the most abundant components of the...; 关键词：Cancer-associated fibroblasts Fibronectin extra domain A Hepatocellular carcinoma Serine hydroxymethyl transferase1 Sorafenib resistance

3-MA对糖尿病小鼠视网膜VEGF和Fibronectin表达的影响: 《中国老年学杂志》2024年第22期5497-5501,共5页张欣怡任海文宫姝玉梦令瑶宋顺琼龚权刘本菊; 国家自然科学基金(82270893);长江大学2021年度大学生创新创业训练计划项目(Yz2021299)。; 目的研究3-甲基腺嘌呤(MA)对糖尿病小鼠视网膜血管内皮生长因子(VEGF)和纤黏蛋白(Fibronectin)表达的影响。方法对糖尿病视网膜病变(DR)基因靶点与3-MA预测基因靶点的共同基因进行生物信息学分析。将雄性C57BL/6J小鼠分为正常对照组、...; 关键词：糖尿病视网膜病变 3-甲基腺嘌呤血管内皮生长因子纤黏蛋白

Brain delivery of fibronectin through bioactive phosphorous dendrimers for Parkinson’s disease treatment via cooperative modulation of microglia: 《Bioactive Materials》2024年第8期45-54,共10页Waicong Dai Mengsi Zhan Yue Gao Huxiao Sun Yu Zou Regis Laurent Serge Mignani Jean-Pierre Majoral Mingwu Shen Xiangyang Shi; supported by the National Natural Science Foundation of China(52350710203 and U23A2096);the Science and Technology Commission of Shanghai Municipality(21490711500,23WZ2503300,23520712500 and 20DZ2254900);the National Key R&D Program(2022YFE0196900);the Shanghai Education Commission through the leading talent program.S.M.and X.S.also acknowledge the support by the Fundaçao para a Ciencia e a Tecnologia(FCT)with Portuguese Government funds through the CQM Base Fund-UIDB/00674/2020(DOI:10.54499/UIDB/00674/2020);Programmatic Fund-UIDP/00674/2020(DOI:10.54499/UIDP/00674/2020).; Effective treatment of Parkinson’s disease(PD),a prevalent central neurodegenerative disorder particularly affecting the elderly population,still remains a huge challenge.We present here a novel nanomedicine formulat...; 关键词：Phosphorous dendrimers FIBRONECTIN Parkinson’s disease Blood brain barrier Combination therapy

miR-34b-3p-mediated regulation of STC2 and FN1 enhances chemosensitivity and inhibits proliferation in cervical cancer: 《Acta Biochimica et Biophysica Sinica》2024年第5期740-752,共13页Shanshan Jin Wenting Wang Xinrui Xu Zhaowei Yu Zihan Feng Jun Xie Huimin Lv; supported by the grants from the Applied Basic Research Programs of Science and Technology Commission Foundation of Shanxi Province(No.20210302124592);the Scientific Research Project of Health Commission of Shanxi Province(No.2021151).; Dysregulation of microRNA(miRNA)expression in cancer is a significant factor contributing to the progression of chemoresistance.The objective of this study is to explore the underlying mechanisms by which miR-34b-3p r...; 关键词：miR-34b-3p CHEMORESISTANCE cervical cancer stanniocalcin 2(STC2) fibronectin 1(FN1) CISPLATIN

Ensemble for evaluating diagnostic efficacy of non-invasive indices in predicting liver fibrosis in untreated hepatitis C virus population: 《World Journal of Methodology》2024年第3期90-105,共16页Navneet Kaur Gitanjali Goyal Ravinder Garg Chaitanya Tapasvi Umit Demirbaga; BACKGROUND Hepatitis C virus(HCV)infection progresses through various phases,starting with inflammation and ending with hepatocellular carcinoma.There are several invasive and non-invasive methods to diagnose chronic ...; 关键词：Hepatitis C virus Non-invasive biomarkers Shear wave elastography FIBRONECTIN Bayesian network Machine learning Liver fibrosis

The role of fibronectin in multiple sclerosis and the effect of drug delivery across the blood-brain barrier被引量：3: 《Neural Regeneration Research》2023年第10期2147-2155,共9页Shuang-Shuang Wei Le Chen Feng-Yuan Yang Si-Qi Wang Peng Wang; supported by the National Natural Science Foundation of China,Nos.82001282(to PW)and 81960232(to PW);Overseas Students’Innovation and Entrepreneurship Individual Project of Ningxia(2021)(to PW);Youth Talents Supporting Program of Ningxia Medical University and Ningxia,Nos.XT2019018(to PW),TJGC2019081(to PW);College Students’Innovation and En trepreneurship Training Program,No.X202210752038(to FYY)。; Remyelination failure is one of the main characteristics of multiple sclerosis and is potentially correlated with disease progression.Previous research has shown that the extracellular matrix is associated with remyel...; 关键词：blood-brain barrier brain delivery EXOSOMES extracellular matrix fibronectin aggregates FIBRONECTIN intestinal flora multiple sclerosis remyelination failure REMYELINATION

M2 macrophages mediate fibrotic scar formation in the early stages after cerebral ischemia in rats被引量：2: 《Neural Regeneration Research》2023年第10期2208-2218,共11页Jia-Gui Huang Jiang-Xia Ren Yue Chen Ming-Fen Tian Li Zhou Jun Wen Xiao-Song Song You-Lin Wu Qing-Huan Yang Pei-Ran Jiang Jia-Ni Wang Qin Yang; supported by the National Natural Science Foundation of China,Nos.82171456 (to QY),81971229 (to QY);the Natural Science Foundation of Chongqing,No.cstc2021jcyj-msxmX0263 (to QY);the Postgraduate Research and Innovation Project of Chongqing,Nos.CYB20151 (to QY),CYS19182 (to YC)。; In the central nervous system, the formation of fibrotic scar after injury inhibits axon regeneration and promotes repair. However, the mechanism underlying fibrotic scar formation and regulation remains poorly unders...; 关键词：central nervous system extracellular matrix FIBRONECTIN fibrotic scar macrophage interleukin 4 ischemic cerebral injury neurological function Sonic hedgehog transforming growth factorβ1

Poly-L-ornithine blocks the inhibitory effects of fibronectin on oligodendrocyte differentiation and promotes myelin repair被引量：3: 《Neural Regeneration Research》2023年第4期832-839,共8页Ya-Jie Xiong Shahid Hussain Soomro Zhong-Hai Huang Pan-Pan Yu Jie Ping Hui Fu; supported by the National Nature Science Foundation of China,Nos.81371338(to HF)and 82071369(PPY)。; The extracellular matrix surrounding oligodendrocytes plays an important role during myelination and remyelination in the brain.In many cases,the microenvironment surrounding demyelination lesions contains inhibitory ...; 关键词：differentiation Erk1/2 extracellular matrix FIBRONECTIN lysolecithin-induced demyelination OLIGODENDROCYTE PI3K poly-L-ornithine proliferation REMYELINATION

Fibronectin 1促进胃癌细胞耐药及其作用机制研究被引量：1: 《肿瘤药学》2023年第1期43-49,共7页岳芙蓉彭科瑜张力张军; 重庆市自然科学基金面上项目(cstc2017jcyj-mxmX3527)。; 目的探讨纤连蛋白1(FN1)促进胃癌细胞耐药及其作用机制。方法选择胃癌细胞系MKN45、MKN45/DDP、MKN45/VCR进行pLV-FN1、pLV-NC、FN1 siRNA慢病毒和脂质体3000瞬时转染,将转染pLVFN1的设为FN1过表达组(FN1),转染pLV-NC的为阴性对照组(Vec...; 关键词：FN1 胃癌耐药增殖凋亡

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