supported by the National Institutes of Health,Nos.AA025919,AA025919-03S1,and AA025919-05S1(all to RAF).
Hippocampal neuronal loss causes cognitive dysfunction in Alzheimer’s disease.Adult hippocampal neurogenesis is reduced in patients with Alzheimer’s disease.Exercise stimulates adult hippocampal neurogenesis in rode...
supported by Cure Alzheimer’s Fund (to RET and SHC);JPB Foundation (to RET),and R56AG072054 (to SHC)。
Irisin is a myokine that is generated by cleavage of the membrane protein fibronectin type Ⅲ domain-containing protein 5(FNDC5) in response to physical exercise. Studies reveal that irisin/FNDC5 has neuroprotective f...
Imagine walking into an exercise studio at the invitation of a friend.Upon entering,you expect to see a room full of cardiovascular and weight-training stations.But instead,you see people holding onto black straps tha...
supported by the STI 2030-Major Projects,No. 2021ZD0200500 (to XS)。
Brain-derived neurotrophic factor is a crucial neurotrophic factor that plays a significant role in brain health. Although the vast majority of meta-analyses have confirmed that exercise interventions can increase bra...
supported by the Swedish Research Council(201500165);a Wallenberg Scholars Award from the Knut and Alice Wallenberg Foundation(KAW 2023.0312);The Novo Nordisk Foundation Center for Basic Metabolic Research is an independent research center at the University of Copenhagen,partially funded by an unrestricted donation from the Novo Nordisk Foundation(NNF23SA0084103).
1.Exercise enhances muscle function and insulin sensitivity Skeletal muscle plays a fundamental role in not only locomotion,but also systemic metabolism.In people with type 2 diabetes,skeletal muscle is a major site o...
There are many things that make me change in the past three years.Most of them make me better.One of the most important changes is I am healthier and stronger because of my exercise.As I ate junk food and seldom exerc...
We read with great interest the recent article by Valenzuela et al.1titled“Dose-response effect of pre-exercise carbohydrates under muscle glycogen unavailability:Insights from McArdle disease”published in the Journ...
supported in part by the intramural research programs at the National Institute on Aging and National Cancer Institute(USA);supported by the Spanish Ministry of Science,Innovation and Universities under Beatriz Galindo's 2022 fellowship program(BG22/00075).
Background:A shift from self-reports to wearable sensors for global physical activity(PA)surveillance has been recommended.The conventional use of a generic cut-point to assess moderate-to-vigorous PA(MVPA)is problema...
supported by Project of the Health Shanghai Initiative Special Fund(Medical-Sports Integration,Creating a New Model of Exercise for Health),No.JKSHZX-2022-02(to SC).
Recent research has demonstrated the impact of physical activity on the prognosis of glioma patients,with evidence suggesting exercise may reduce mortality risks and aid neural regeneration.The role of the small ubiqu...
In this article,we discuss the recently published article by Soni et al.This study explores the effectiveness of a comprehensive digital health program,RESET care,which integrates personalized dietary plans,structured...