SKELETAL

作品数：352被引量：497H指数：10
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相关领域：医药卫生更多>>
相关作者：周婷婷李惠怡雷勇华李静先李晖更多>>
相关机构：第二军医大学重庆医科大学中南大学天津运动医学研究所更多>>
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相关基金：国家自然科学基金北京市自然科学基金中国博士后科学基金国家重点基础研究发展计划更多>>
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Hypophosphatasia:A case report
《World Journal of Clinical Cases》2025年第21期71-77,共7页Angad Singh Gill Pallavi Sharma Mahmoud Nassar Erlin Marte 
BACKGROUND Hypophosphatasia(HPP)is a rare metabolic disorder caused by low tissue-nonspecific alkaline phosphatase(ALP)activity,presenting symptoms from bone demineralization to tooth loss.It affects multiple systems ...
关键词：HYPOPHOSPHATASIA Tissue-nonspecific alkaline phosphatase OSTEOPENIA Enzyme replacement therapy Asfotase alfa Low alkaline phosphatase levels Vitamin B6 metabolism Skeletal hypomineralization Rare metabolic disorders Adultonset hypophosphatasia Case report 
Improved superelastic Ni-Ti alloy wire for treating skeletal class III malocclusion combined with anterior crossbite:A case report
《World Journal of Clinical Cases》2025年第18期34-45,共12页Yu-Hsiang Sean Chang Yuan-Hou Chen Jian-Hong Yu 
BACKGROUND Correcting skeletal class III malocclusion with anterior crossbite in adolescents using only orthodontic treatment poses challenges.This report highlights a novel approach leveraging improved superelastic N...
关键词：Orthodontics Skeletal class III malocclusion Anterior crossbite Improved superelastic Ni-Ti alloy wire Multi-bend edgewise archwire Intermaxillary elastics Case report 
Advancing skeletal health and disease research with single-cell RNA sequencing
《Military Medical Research》2025年第2期285-310,共26页Peng Lin Yi-Bo Gan Jian He Si-En Lin Jian-Kun Xu Liang Chang Li-Ming Zhao Jun Zhu Liang Zhang Sha Huang Ou Hu Ying-Bo Wang Huai-Jian Jin Yang-Yang Li Pu-Lin Yan Lin Chen Jian-Xin Jiang Peng Liu 
National Key Research and Development Program of China(2022YFA1103202);National Natural Science Foundation of China(82272507,32270887,and 32200654);Natural Science Foundation of Chongqing(CSTB2023NSCQ-ZDJO008);Postdoctoral Innovative Talent Support Program(BX20220397);Independent Research Project of State Key Laboratory of Trauma and Chemical Poisoning(SFLKF202201);Project for Enhancing Innovation of Army Medical University(2023X1839);Talent Innovation Training Program at the Army Medical Center(ZXZYTSYS09);General Hospital of Western Theater Command Research Project(2021-XZYG-B10);University Grants Committee,Research Grants Council of Hong Kong,China(14113723,N_CUHK472/22,C7030-18G,T13-402/17-N,and AoE/M-402/20)。
Orthopedic conditions have emerged as global health concerns,impacting approximately 1.7 billion individuals worldwide.However,the limited understanding of the underlying pathological processes at the cellular and mol...
关键词：Skeletal disorders Musculoskeletal system Single-cell RNA sequencing(scRNA-seq) Cellular heterogeneity Single cell suspension Bioinformatic analysis 
Study on the sliding tribological behavior of ZIF-8 under lubricating grease conditions
《Nanotechnology and Precision Engineering》2025年第1期25-35,共11页Ling Pan Zhi Li Yunli Wu Kaikui Zheng Yuqing Han 
supported by the National Natural Science Foundation of China(52275178);the Fujian Industry University Cooperation Project(2020H6025)。
ZIF-8 is widely applied in lubrication,adsorption,and catalysis owing to its unique physicochemical properties.Previous experimental studies have demonstrated its feasibility as a lubricant additive.In the present wor...
关键词：Antifriction mechanism ZIF-8 Skeletal material Molecular dynamics Lubricant additive Lithium-based grease 
Skeletal interoception and prospective application in biomaterials for bone regeneration
《Bone Research》2025年第1期1-14,共14页Long Bai Jilong Li Guangfeng Li Dongyang Zhou Jiacan Su Changsheng Liu 
National Natural Science Foundation of China(82230071,82172098);Integrated Project of Major Research Plan of National Natural Science Foundation of China(92249303);Shanghai Committee of Science and Technology(23141900600,Laboratory Animal Research Project);Shanghai Clinical Research Plan of SHDC2023CRT01;Young Elite Scientist Sponsorship Program by China Association for Science and Technology(YESS20230049)。
Accumulating research has shed light on the significance of skeletal interoception,in maintaining physiological and metabolic homeostasis related to bone health.This review provides a comprehensive analysis of how ske...
关键词：HOMEOSTASIS BIOMATERIALS utilize 
Investigating the Relationship between Age-Related Cardiac Hypertrophy, Skeletal Muscle Strength, and the FNDC5 Protein as a Potential Regulator
《Journal of Biosciences and Medicines》2025年第2期450-464,共15页Tao Feng Ziyang Fang Yinjun Luo Xin Zhang Ying Li Shijing Ma Jinting Wei Xiaoyan Fang Biao Li Lingling Huang Jinhua Wang Suchan Liao 
Background: Aging-induced cardiac hypertrophy and reduced skeletal muscle strength contribute to increased disease risk and life burden in the elderly. FNDC5 acts as a protective muscle factor in both cardiac and skel...
关键词：AGING Heart Hypertrophy Skeletal Muscle FNDC5 
Roles of N-cadherin in cerebral cortical development:cooperation with membrane trafficking and actin cytoskeletal regulation
《Neural Regeneration Research》2025年第1期188-190,共3页Shiho Ito Takeshi Kawauchi 
funded by JSPS KAKENHI Grant Numbers JP26290015 and JP21H02655(to TK)from Ministry of Education,Culture,Sports,Science,and Technology of Japan(MEXT)。
Cell adhesion plays pivotal roles in the morphogenesis of multicellular organisms.Epithelial cells form several types of cell-to-cell adhesion,including zonula occludens(tight junctions),zonula adhaerens(adherens junc...
关键词：CEREBRAL SKELETAL COOPERATION 
In vivo analysis of hybrid hydrogels containing dual growth factor combinations,and skeletal stem cells under mechanical stimulation for bone repair
《Mechanobiology in Medicine》2024年第4期97-109,共13页David Gothard Michael Rotherham Emma L.Smith Janos M.Kanczler James Henstock Julia A.Wells Carol A.Roberts Omar Qutachi Heather Peto Hassan Rashidi Luis Rojo Lisa J.White Molly M.Stevens Alicia J.El Haj Felicity R.J.ose Richard O.C.Oreffo 
supported by the BBSRC(sLOLA grant BB/G010579/1);an EU ERC Advanced Grant DYNACEUTICS(grant no.789119).
Bone tissue engineering requires a combination of materials,cells,growth factors and mechanical cues to recapitulate bone formation.In this study we evaluated hybrid hydrogels for minimally invasive bone formation by ...
关键词：Growth factors Controlled release Bone ECM Bone formation MECHANOTRANSDUCTION Skeletal stem cell 
Skeletal organoids
《Biomaterials Translational》2024年第4期390-410,共21页Chen Zhang Yingying Jing Jianhua Wang Zhidao Xia Yuxiao Lai Long Bai Jiacan Su 
financially supported by National Natural Science Foundation of China(Nos.32471396,82230071,82172098);Integrated Project of Major Research Plan of National Natural Science Foundation of China(No.92249303);Shanghai Committee of Science and Technology(No.23141900600,Laboratory Animal Research Project);Shanghai Clinical Research Plan(No.SHDC2023CRT01);Shanghai Municipal Demonstration Project for Innovative Medical Device Applications(No.23SHS05700);Young Elite Scientist Sponsorship Program by China Association for Science and Technology(No.YESS20230049).
The skeletal system,composed of bones,muscles,joints,ligaments,and tendons,serves as the foundation for maintaining human posture,mobility,and overall biomechanical functionality.However,with ageing,chronic overuse,an...
关键词：APPLICATIONS construction strategies ORGANOIDS skeletal system 
Prenatal and postnatal imaging of osteogenesis imperfecta: a case report
《镜湖医学》2024年第2期56-57,16,共3页IP Lao Hong LI Jun 
Introduction.Osteogenesis imperfecta(OI),also known as brittle bone disease,is a phenotypically diverse disorder due to deficiencies in the synthesis of type I collagen.OI is a disease characterized by brittle bones a...
关键词：imperfect SKELETAL bones 
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