Adult neurogenesis is a highly dynamic process that leads to the production of new neurons from a population of quiescent neural stem cells(NSCs).In response to specific endogenous and/or external stimuli,NSCs enter a...
supported by Basic Research Programs of Science and Technology Commission Foundation of Shanxi Province,No.20210302123486(to WJ).
Epilepsy,a common neurological disorder,is characterized by recurrent seizures that can lead to cognitive,psychological,and neurobiological consequences.The pathogenesis of epilepsy involves neuronal dysfunction at th...
Autophagy plays a crucial role in axon regeneration by maintaining cellular homeostasis and promoting the clearance of damaged organelles and proteins,which is essential for the growth and repair of axons.In response ...
supported by Grants from Spanish FEDER/Science and Innovation Ministry I+D+i-RETOS-PID2021-124801NB-100;Centro de Investigacion Biomedica en Red sobre Enfermedades Neurodegenerativas(CIBERN ED;an initiative of the ISCIII)[PI2016/01];the Fundocion Ramon Areces and Banco Santander to the CBMSO(to FW)。
Autophagy is a cellular degradation and recycling system,indispensable for cellular and organ development,homeostasis,and function.This cellular process is evolutionarily highly conserved to quality control of many pr...
Brain-derived neurotrophic factor(BDNF)exerts pleiotropic effects on brain processes including psychiatric disorders,aging,neurodegeneration,and metabolic homeostasis.A simple PubMed search using the key word“BDNF,”...
supported by funding from the National Institutes of Health(R01 NS117510)(to RLM)。
Heterogeneous proper t i es of vascular endothelial cells in the brain:The brain displays large energy dynamics and consumption,and this high level of metabolic demands is fulfilled by a continuous supply of glucose a...
The umbrella term"neurodege ne rative disorders"(NDDs) refers to several conditions characterized by a progressive loss of structure and function of cells belonging to the nervous system.Such diseases affect more than...
received funding from the Natural Science Foundation of Shandong Province(No.ZR2023MC141);the Innovation and Entrepreneurship Training Program for College Students(No.202210435003);financial support was also provided by the‘First Class Fishery Discipline’Program and the Special Talent Program‘One Thing One Decision(Yishi Yiyi)’in Shandong Province,China。
The Chinese seabass(Lateolabrax maculatus)is one of the most popular and valuable aquaculture species in China.Recently,the disease caused by Vibrio anguillarum has brought huge economic losses in the L.maculatus indu...
supported by the National Natural Science Foundation of China (No.32272893);the Program of the Giant Panda Breeding Research Foundation (China) (No.2020CPB-C10).
Obesity related metabolic diseases,including non-alcoholic fatty liver disease,insulin resistance,hyperglycemia,and hyperlipemia,have become major chronic diseases.i,2 As an important enzyme for ATP production,3 ATP5b...
Although metabolic homeostasis disruption,cellular damage,and premature senescence caused by salinity stress are well-documented in the literature,there are few studies investigating cytological changes induced by sal...