supported by Basic Research Programs of Science and Technology Commission Foundation of Shanxi Province,No.20210302123486(to WJ).
Epilepsy,a common neurological disorder,is characterized by recurrent seizures that can lead to cognitive,psychological,and neurobiological consequences.The pathogenesis of epilepsy involves neuronal dysfunction at th...
supported by Swiss Center for Applied Human Toxicology(SCAHT AP22-01)(to RN).
Alzheimer’s disease(AD)is the most common cause of dementia,characterized by progressive cognitive decline,and affects over 55 million people worldwide.AD is pathological featured by the aberrant accumulation of amyl...
supported by the National Natural Science Foundation of China,Nos.81772453(to DX),81974358(to DX),81973157(to JZ),82173646(to JZ),82302866(to YZ)。
Promoting synaptic plasticity and inducing functional reorganization of residual nerve fibers hold clinical significance for restoring motor function following spinal cord injury.Neuromagnetic stimulation targeting th...
Alzheimer's disease is a common neurodegenerative disorder in older adults.Despite its prevalence,its pathogenesis remains unclea r.In addition to the most widely accepted causes,which in clude excessive amyloid-beta ...
Alcohol use disorder(AUD)is a medical condition that impairs a person's ability to stop or manage their drinking in the face of negative social,occupational,or health consequences.AUD is defined by the National Instit...
sponsored by the National Natural Science Foundation of China(62121003,T2293730,T2293731,61960206012,62333020,and 62171434);the National Key Research and Development Program of China(2022YFC2402501 and 2022YFB3205602);the Major Program of Scientific and Technical Innovation 2030(2021ZD02016030)。
Intracortical neural interfaces directly connect brain neurons with external devices to achieve high temporal resolution and spatially precise sampling of neural activity.When applied to freely moving animals,this tec...
This work was supported by the Princess Nourah bint Abdulrahman University Researchers Supporting Project number(PNURSP2025R73);Princess Nourah bint Abdulrahman University,Riyadh,Saudi Arabia,and researchers supporting project number(RSPD2025R885)at King Saud University Riyadh Saudi Arabia。
Objective:To investigate the effect of Rosa moschata(R.moschata)extract on haloperidol-induced Parkinson’s disease(PD)in rats.Methods:Haloperidol(1 mg/kg)was given to rats intraperitoneally for 3 weeks for induction ...
supported by the National Natural Science Foundation of China(Grant No.62074163);Beijing Natural Science Foundation(Grant No.JQ24030).
Organic electrochemical transistors have emerged as a solution for artificial synapses that mimic the neural functions of the brain structure,holding great potentials to break the bottleneck of von Neumann architectur...
supported by the National Natural Science Foundation of China(81973639 and 81573712);the Innovative Research Team of High-level Local Universities in Shanghai.We appreciate the technical support provided by the Shanghai Key Laboratory for Acupuncture Mechanism and Acupoint Function(21DZ2271800).
Neurotransmitter switching,as a novel form of neural plasticity,is characterized by the gradual loss of one neurotransmitter and its transformation into another novel neurotransmitter within neurons.Correspondingly,po...
funded by the National Key R&D Program of China(to Z.Z.,2021YFA1302300);the National Natural Science Foundation of China(to Z.Z.,32171201);the Science Fund for Creative Research Groups of the National Natural Science Foundation of China(to C.S.,T2321001);the STI2030-Major Projects(to Yixiao Z.,2022ZD0207400);the Basic Research Pioneer Project of the Science and Technology Commission of Shanghai Municipality(STCSM,to Yixiao Z.);The study was also supported in part by the Center for Life Sciences(CLS),School of Life Sciences(SLS)of Peking University,the State Key Laboratory of Membrane Biology of China,the Frontier Innovation Fund of Peking University Chengdu Academy for Advanced Interdisciplinary Biotechnologies(to Z.Z.),and ALSAC(to C.-H.L.).
Dear Editor,Acetylcholine(ACh)is an excitatory neurotransmitter with a wide variety of functions.In the central nervous system,ACh helps regulate memory,motivation,arousal,and attention.ACh controls muscle contraction...