funded by the National Key R&D Program of China(to Z.Z.,2021YFA1302300);the National Natural Science Foundation of China(to Z.Z.,32171201);the Science Fund for Creative Research Groups of the National Natural Science Foundation of China(to C.S.,T2321001);the STI2030-Major Projects(to Yixiao Z.,2022ZD0207400);the Basic Research Pioneer Project of the Science and Technology Commission of Shanghai Municipality(STCSM,to Yixiao Z.);The study was also supported in part by the Center for Life Sciences(CLS),School of Life Sciences(SLS)of Peking University,the State Key Laboratory of Membrane Biology of China,the Frontier Innovation Fund of Peking University Chengdu Academy for Advanced Interdisciplinary Biotechnologies(to Z.Z.),and ALSAC(to C.-H.L.).
Dear Editor,Acetylcholine(ACh)is an excitatory neurotransmitter with a wide variety of functions.In the central nervous system,ACh helps regulate memory,motivation,arousal,and attention.ACh controls muscle contraction...
BACKGROUND Immune-mediated necrotizing myopathy is a rare autoimmune myopathy characterized by muscle weakness and elevated serum creatine kinase,with unique skeletal muscle pathology and magnetic resonance imaging fe...
Introduction: Myasthenia gravis is a chronic autoimmune neuromuscular disease, presents with weakness and fatigability of striated skeletal muscles. It is a rare disease in Cameroon. We report an uncommon case of myas...
Objective To observe the curative effect of needle roller combined with Qiangli Yiqi Prescription(QLYQP)on myasthenia gravis(MG)patients with Pi-qi deficiency and on the levels of inflammatory factors such as interleu...
Objective To determine the correlation between the titer of anti-muscle-specific tyrosine kinase(anti-MuSK)antibodies(Abs)and the severity and prognosis of Musk-associated myasthenia gravis(Musk-MG).Methods A total of...
Objective To describe clinical characteristics,genetic mutation and therapeutic response of a family diagnosed as slow-channel congenital myasthenia syndrome(SCCMS) and analyze the factors of the efficacy of channel b...
We report four observations of myasthenia gravis associated with other autoimmune diseases. Myasthenia gravis can be associated with all autoimmune diseases with a predominance of dysthyroidism. Among the autoimmune d...
Introduction: Myasthenia is a rare and disabling autoimmune disease. Few studies were devoted to this pathology. We report a clinical case of myasthenia in the Department of Internal Medicine at the Point G University...
The anaesthetic management of the pregnant woman with myasthenia gravis (MG) is very challenging to the anaesthesiologist. This situation becomes exaggerated in emergency settings in a low resource area, especially wh...
Background: Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease involving both upper and lower neurons with no effective cure. Electrophysiological studies have found decremental responses d...