Immune-mediated necrotizing myopathy:Report of two cases  

作　　者：Bi-Hong Chen Xue-Min Zhu Lei Xie Huai-Qiang Hu 

机构地区：[1]Department of Clinical Medicine,Weifang Medical University,Weifang 261053,Shandong Province,China [2]School of Clinical Medicine,Weifang Medical University,Weifang 261053,Shandong Province,China [3]Department of Neurology,The 960th Hospital of People′s Liberation Army,Jinan 250031,Shandong Province,China

出　　处：《World Journal of Clinical Cases》2023年第15期3552-3559,共8页世界临床病例杂志

摘　　要：BACKGROUND Immune-mediated necrotizing myopathy is a rare autoimmune myopathy characterized by muscle weakness and elevated serum creatine kinase,with unique skeletal muscle pathology and magnetic resonance imaging features.CASE SUMMARY In this paper,two patients are reported:One was positive for anti-signal recognition particle antibody,and the other was positive for anti-3-hydroxy-3-methylglutaryl coenzyme A reductase antibody.CONCLUSION The clinical characteristics and treatment of the two patients were analysed,and the literature was reviewed to improve the recognition,diagnosis,and treatment of this disease.

关 键 词：Immune-mediated necrotizing myopathy Anti-signal recognition particle antibody Anti-3-hydroxy-3-methylglutaryl coenzyme A reductase antibody MYASTHENIA Muscle magnetic resonance Muscle pathology Case report 

分 类 号：R593.2[医药卫生—内科学]