ALCOHOL

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Acid-sensing ion channel 1a promotes alcohol-associated liver disease in mice via regulating endoplasmic reticulum autophagy
《Acta Pharmacologica Sinica》2025年第4期989-1001,共13页Yue-qin Zhu Li-li Wang Zi-hao Li Shi-shun Qian Zhou Xu Jin Zhang Yong-hu Song Xue-sheng Pan Na Du Amira Abou-Elnour Lynn Jia Tay Jing-rong Zhang Meng-xue Li Yu-xian Shen Yan Huang 
supported by the National Natural Science Foundation of China(82370591);Key Project of the Joint Fund of the National Natural Science Foundation of China(U21A20345);the Fundamental Research Funds for the Central Universities(WK9110000197);the Anhui Province Higher Education Science Research Project(Natural Science)(2023AH040078);the Horizontal Project(H2023031);the 2021 Academic Funding Project for Top Talents in Higher Education Discipline(Major)(gxbjZD2021048);the 2023 Hefei Natural Science Foundation Project(2023018);the 2023 Anhui Medical University Research Level Improvement Plan Project(2023xkiT010);Pharmaceutical Peak Discipline Talent Fund Project“Research oriented Young Talents”(2023xkkq3);Anhui Province Excellent Research and Innovation Team Project(2024AH010013);the Anhui Medical University International Students Innovation Training Program Project(GJY202305;S202410366120);the 2023 New Era Education Provincial Quality Engineering Project Graduate Joint Training Demonstration Base[2023lhpysfjd023];the Early Contact Research Projects(2022-ZQKY-80;2023-YXYZQKY-40).
Alcohol-associated liver disease(ALD)is a hepatocyte dysfunction disease caused by chronic or excessive alcohol consumption,which can lead to extensive hepatocyte necrosis and even liver failure.Currently,the pathogen...
关键词：alcohol-associated liver disease ASIC1a Ca^(2+)influx ER-phagy ER stress apoptosis 
Alcohol regulated phase change absorbent for efficient carbon dioxide capture:Mechanism and energy consumption
《Journal of Environmental Sciences》2025年第4期440-450,共11页Chen Wang Weixin Kong Zhangfeng Dong Bihong Lv Guohua Jing Zuoming Zhou 
supported by the National Natural Science Foundation of China(Nos.22278168 and 22276064);the MOE Key Laboratory of Resources and Environmental System Optimization(No.KLRE-KF202205);the Science and Technology Project of Fujian province(No.2022Y3007).
Phase change absorbents based on amine chemical absorption for CO_(2)capture exhibit energy-saving potential,but generally suffer from difficulties in CO_(2)regeneration.Alcohol,characterized as a protic reagent with ...
关键词：Biphasic solvent Organic alcohols activator Regenerability Energy consumption 
Alcohol and alcoholism associated neurological disorders:Current updates in a global perspective and recent recommendations
《World Journal of Experimental Medicine》2025年第1期24-40,共17页Prashanti Sahu Henu Kumar Verma LVKS Bhaskar 
Alcohol use disorder(AUD)is a medical condition that impairs a person's ability to stop or manage their drinking in the face of negative social,occupational,or health consequences.AUD is defined by the National Instit...
关键词：ALCOHOL ALCOHOLISM NEUROTRANSMITTER Neurological disorders Alcohol metabolism 
Smartphone-based Stroop Test,EncephalApp:What is the optimal cutoff for diagnosing minimal hepatic encephalopathy?
《World Journal of Hepatology》2025年第3期225-228,共4页Ryota Masuzaki Hirofumi Kogure 
Jiang et al explored the diagnostic capabilities of EncephalApp,a smartphone-based Stroop Test,in patients with nonalcoholic liver disease.The study included 160 patients with nonalcoholic cirrhosis and utilized the p...
关键词：Minimal encephalopathy Liver cirrhosis Portal hypertension Stroop test Alcohol-related liver disease Metabolic dysfunction-associated liver disease 
Photocatalytic,electrocatalytic and photoelectrocatalytic conversion of methane to alcohol
《Chinese Journal of Catalysis》2025年第3期207-229,共23页Yu Huang Lei Zou Yuan-Biao Huang Rong Cao 
国家重点研发计划(2023YFA1507904);国家自然科学基金(22401280,U22A20436,22071245,22220102005,22033008);福建省自然科学基金(2024J08104);中国福建光电信息科学与技术创新实验室(2021ZZ103).
The conversion of the greenhouse gas methane to value-added chemicals such as alcohols is a promising technology to mitigate environmental issue and the energy crisis.Especially,the sustainable photocatalytic,electroc...
关键词：Photocatalysis ELECTROCATALYSIS PHOTOELECTROCATALYSIS Methane conversion ALCOHOL 
Effect of surface species on the alcohol-acid adsorption from FTS wastewater on graphene:A structure-capacity study
《Journal of Environmental Sciences》2025年第3期651-662,共12页Xiao Liu Xiaolong Zhang Chunyu Geng Qinglan Hao Jie Chang Xin Hu Yongwang Li Botao Teng 
supported by the National Natural Science Foundation of China(Nos.22372120 and 21872125);the Foundation of State Key Laboratory of Coal Conversion(No.J2122908);the Synfuels China Co.,Ltd.
Fischer-Tropsch synthesis(FTS)wastewater retaining low-carbon alcohols and acids are organic pollutants as a limiting factor for FTS industrialization.In this work,the structurecapacity relationships between alcohol-a...
关键词：Alcohol-acid adsorption Fischer-Tropsch synthesis WASTEWATER GRAPHENE Surface species Density functional theory 
Effect of frailty as measured by functional impairment on long-term outcomes in liver transplantation in the United States
《World Journal of Transplantation》2025年第2期205-217,共13页Julius Balogh Talha Mubashir Yuan Li Biai D Digbeu Nikita Hegde Fatemeh Movaghari Pour Mohsen Rezapour Hong-Yin Lai Kelly West Rabail A Chaudhry George W Williams Vahed Maroufy 
BACKGROUND In patients with chronic liver disease or hepatic dysfunction with sarcopenia,there is an increased risk of frailty as measured by functional impairment,making frailty a vital predictor of post-transplant m...
关键词：Non-alcoholic steatotic liver disease Alcohol-associated liver disease Liver transplantation Non-alcoholic steatohepatitis Insulin resistance Oxidative stress 
Rab11b promotes M1-like macrophage polarization by restraining autophagic degradation of NLRP3 in alcohol-associated liver disease
《Acta Pharmacologica Sinica》2025年第1期134-146,共13页Yu-xin Zhao Ying-yin Sun Liang-yun Li Xiao-feng Li Hai-di Li Xin Chen Ran Xia Ying-Li Yang Xin-yu Jiang Long-quan Zuo Xiao-ming Meng Hua Wang Cheng Huang Jun Li 
This project was supported by the National Natural Science Foundation of China(82370630,82100627,82300722);Research Fund of Anhui Institute of Translational Medicine(2021zhyx-B06,2022zhyx-B07);Natural Science Foundation of Anhui Province(2108085QH311,2308085QH248);China Postdoctoral Science Foundation(2022M710178);Anhui Fund for Distinguished Young Scholars(2022AH020050);Postgraduate Innovation Research and Practice Program of Anhui Medical University(YJS20230056);Scientific Research Promotion Fund of Anhui Medical University(2022xkjT010);Scientific Research Platform Improvement Project of Anhui Medical University(2022xkjT045).
Macrophage polarization is vital to mounting a host defense or repairing tissue in various liver diseases.Excessive activation of the NLR family pyrin domain containing 3(NLRP3)inflammasome is related to the orchestra...
关键词：ALD NLRP3 AUTOPHAGY Rab11b inflammation 
Preparation of Co/S co-doped carbon catalysts for excellent methylene blue degradation
《International Journal of Minerals,Metallurgy and Materials》2025年第1期169-181,共13页Haixu Li Haobo He Tiannan Jiang Yunfei Du Zhichen Wu Liang Xu Xinjie Wang Xiaoguang Liu Wanhua Yu Wendong Xue 
financially supported by the National Natural Science Foundation of China(Nos.51602018 and 51902018);the Natural Science Foundation of Beijing Municipality(No.2154052);the China Postdoctoral Science Foundation(No.2014M560044);the Fundamental Research Funds for the Central Universities(No.FRF-MP-20-22);USTB Research Center for International People-to-people Exchange in Science,Technology and Civilization(No.2022KFYB007);Education and Teaching Reform Foundation at University of Science and Technology Beijing(Nos.2023JGC027,KC2022QYW06,and KC2022TS09)。
S and Co co-doped carbon catalysts were prepared via pyrolysis of MOF-71 and thiourea mixtures at 800℃at a mass ratio of MOF-71 to thiourea of 1:0.1 to effectively activate peroxymonosulfate(PMS)for methylene blue(MB...
关键词：advanced oxidation process alcohol solvent evaporation hydrogen bond S and Co co-doped carbon catalysts wastewater remediation 
Prospects of elafibranor in treating alcohol-associated liver diseases
《World Journal of Gastroenterology》2025年第2期132-137,共6页Wei-Tong Cui Hua-Ru Xue Dian-Fang Wei Xiao-Yu Feng Kai Wang 
Supported by Natural Science Foundation of Shandong Province,China,No.ZR2019PC053;the Projects of Medical and Health Technology Development Program in Shandong Province,China,No.202202020837 and No.202301040472.
Alcohol-related liver disease(ALD),which is induced by excessive alcohol con-sumption,is a leading cause of liver-related morbidity and mortality.ALD pa-tients exhibit a spectrum of liver injuries,including hepatic st...
关键词：Elafibranor Alcohol-associated liver diseases Peroxisome proliferator-activated receptor LIPID Apoptosis STEATOSIS Inflammation FIBROSIS 
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