SEIZURE

作品数：253被引量：310H指数：8
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相关机构：广州市妇女儿童医疗中心浙江大学医学院附属第二医院墨尔本大学南京医科大学更多>>
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Neural circuit mechanisms of epilepsy:Maintenance of homeostasis at the cellular,synaptic,and neurotransmitter levels
《Neural Regeneration Research》2026年第2期455-465,共11页Xueqing Du Yi Wang Xuefeng Wang Xin Tian Wei Jing 
supported by Basic Research Programs of Science and Technology Commission Foundation of Shanxi Province,No.20210302123486(to WJ).
Epilepsy,a common neurological disorder,is characterized by recurrent seizures that can lead to cognitive,psychological,and neurobiological consequences.The pathogenesis of epilepsy involves neuronal dysfunction at th...
关键词：chemical genetics hippocampus literature review neural circuits NEUROTRANSMITTER OPTOGENETICS pathogenesis SEIZURE synapses THALAMUS 
Investigation of epilepsy-related genes in a Drosophila model
《Neural Regeneration Research》2026年第1期195-211,共17页Xiaochong Qu Xiaodan Lai Mingfeng He Jinyuan Zhang Binbin Xiang Chuqiao Liu Ruina Huang Yiwu Shi Jingda Qiao 
supported by the Guangdong Basic and Applied Basic Research Foundation,No.2022A1515111123(to JQ)。
Complex genetic architecture is the major cause of heterogeneity in epilepsy,which poses challenges for accurate diagnosis and precise treatment.A large number of epilepsy candidate genes have been identified from cli...
关键词：Drosophila melanogaster ELECTROPHYSIOLOGY EPILEPSY GENETICS morphology neurogenetic diseases POLYGENE precision medicine seizure behavior UAS/GAL4 system 
Seizure first aid in the community:current situation,suggestions,and the role of the general practitioner in seizure management
《Acta Epileptologica》2025年第1期45-56,共12页Mengtian Sun Fanlong Meng Zheng‑yan‑ran Xu Yi Guo 
supported by grants from National Natural Science Foundation of China[grant number 82371450];the Science and Technology Program of Zhejiang Province[grant number 2022C03136].
The unpredictability of seizures underscores the importance of timely recognition and intervention for optimal prognosis.Seizure first aid(SFA)is an essential skill for community members.We reviewed the literature to ...
关键词：SEIZURE First aid COMMUNITY TRAINING General practitioner 
Research on Key Technologies of Wearable Epilepsy Seizure Monitoring and Alarm Devices
《IJLAI Transactions on Science and Engineering》2025年第1期66-71,共6页Xiwei Xu Weirong Zhang 
supported by the Weifang Science and Technology Development Plan under Grant No.2022GX023.
Epilepsy is a common and frequently occurring disease of the nervous system.Long term recurrent epileptic seizures seriously endanger the physical and mental health of patients,and also have profound impacts on famili...
关键词：EPILEPSY intelligent monitoring wearable intelligent device 
Fasciola cinereum:a novel choke point for epilepsy treatment
《Acta Epileptologica》2025年第1期142-144,共3页Lilong Yu Dongxiao Jiang Yi Wang Zhong Chen Lin Yang 
supported by grants from the National Natural Science Foundation of China(82373859);the China Postdoctoral Science Foundation(2023M743145).
Ablation of seizure foci represents a crucial therapeutic approach for epilepsy.Traditionally,the seizure foci are predominantly located in the anterior hippocampus and amygdala.However,recent research by Ivan Soltesz...
关键词：Fasciola cinereum Seizure node Epilepsy treatment 
Inhalation of 5%CO_(2)and activation of ASIC1a:a potential therapeutic approach for Dravet syndrome
《Acta Epileptologica》2025年第1期114-123,共10页Qian Lu Qi Zhang Yangyang Wang Jia Wang Haiqing Zhao Qiuhong Wang Liping Zou 
supported by grants from the Beijing E-Town Cooperation&Development Foundation(YCXJ-JZ-2022–007).
Background Preferential activation of Acid-sensing ion channel 1a(ASIC1a)by acidosis promotes seizure termination.Studies have found that CO_(2)can reduce neuronal excitability and inhibit seizure activity.Dravet synd...
关键词：Dravet syndrome CO_(2) ASIC1a SEIZURE SCN1A 
Antiepileptic activity and potential mechanism of full-spectrum hemp extract
《Fundamental Research》2025年第1期379-380,共2页Zengliang Jin Zhuo Huang 
Epilepsy is the fourth most common neuropsychiatric disorder.Although the approval of Epidiolex has ignited hope for patients,there is still a large gap in the field of anti-seizure research.The effect and underlying ...
关键词：HEMP CANNABINOIDS PHARMACOKINETICS Anti-seizure drugs GABA_(A)receptor 
Rauvolfa vomitoria phenol extract relieves pentylenetetrazol-induced seizures in Swiss mice and protects some temporal lobe structures
《Acta Epileptologica》2024年第4期303-317,共15页Moses B.Ekong Okokon O.Bassey Deborah I.Ebeh Godslove D.Usukuma Darlington C.Samuel Rosemary B.Bassey Aniekan I.Peter Christopher C.Mbadugha Jude E.Okokon Monday I.Akpanabiatu 
supported in part by the Tertiary Education Trust Fund(TETFund).The International Brain Research Organization(IBRO)Early Career Grant and the International Society for Neurochemistry(ISN)Committee for Aid and Education in Neurochemistry(CAEN)provided the funding for small equipment.
Background Rauvolfa vomitoria(R.vomitoria)is a plant of economic importance due to its diverse ethnomedicinal properties,including the anticonvulsant efect.In this study,we studied the antiseizure and neuroprotective ...
关键词：SEIZURE Cognitive behaviour Neurochemicals Temporal lobe Sodium valproate Swiss mice 
SLC2A1 variants cause late-onset epilepsy and the genetic-dependent stage feature
《Acta Epileptologica》2024年第4期318-326,共9页Dongming Zhang Jing Guo Zisheng Lin Hongjun Yan Kai Peng Linxia Fei Qiongxiang Zhai Dongfang Zou Jiayi Zhong Yan Ding Hong Ye Pengyu Wang Jie Wang Sheng Luo Bingmei Li Bin Li Weiping Liao 
supported by the National Natural Science Foundation of China(82271505 to W.L.);UCB Pharma Ltd.and the Joint Science Research Foundation of China Association Against Epilepsy(CU-2024-042 to B.L.).
Background The SLC2A1 gene plays a vital role in brain energy metabolism.SLC2A1 variants have been reported to be associated with early-onset refractory seizures.This study aims to explore the association between the ...
关键词：SLC2A1 gene Glucose transporter type 1 defciency syndrome Mild epilepsy Genetic dependent stage Seizure-onset age 
Optimizing anesthesia depth to enhance seizure quality during electroconvulsive therapy in major depressive disorder
《World Journal of Psychiatry》2024年第12期1788-1792,共5页Haewon Byeon 
Supported by Basic Science Research Program through the National Research Foundation of Korea(NRF)funded by the Ministry of Education,No.NRF-RS-2023-00237287 and No.NRF-2021S1A5A8062526;Local Government-University Cooperation-Based Regional Innovation Projects,No.2021RIS-003.
This editorial evaluated the findings of a comprehensive study focused on the effects of anesthesia depth on seizure parameters during electroconvulsive therapy(ECT)in patients with major depressive disorder.The study...
关键词：Electroconvulsive therapy Anesthesia depth Major depressive disorder Electroencephalography seizure parameters Quantitative consciousness index Quantitative nociceptive index Seizure quality Editorial 
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