Fasciola cinereum:a novel choke point for epilepsy treatment  

作　　者：Lilong Yu Dongxiao Jiang Yi Wang Zhong Chen Lin Yang 

机构地区：[1]Key Laboratory of Neuropharmacology and Translational Medicine of Zhejiang Province,The First Affiliated Hospital,School of Pharmaceutical Sciences,Zhejiang Chinese Medical University,Hangzhou,310053,China [2]Institute of Pharmacology&Toxicology,College of Pharmaceutical Sciences,School of Medicine,Zhejiang University,Hangzhou,310053,China

出　　处：《Acta Epileptologica》2025年第1期142-144,共3页癫痫学报(英文)

基　　金：supported by grants from the National Natural Science Foundation of China(82373859);the China Postdoctoral Science Foundation(2023M743145).

摘　　要：Ablation of seizure foci represents a crucial therapeutic approach for epilepsy.Traditionally,the seizure foci are predominantly located in the anterior hippocampus and amygdala.However,recent research by Ivan Soltesz and his colleagues described the posterior hippocampal fasciola cinereum(FC)as a region activated during seizures.Their findings demonstrate that inhibition and ablation of FC reduce seizures frequency.Therefore,FC emerges as a critical seizure node within the posterior hippocampus,playing an important role in epilepsy treatment.

关 键 词：Fasciola cinereum Seizure node Epilepsy treatment 

分 类 号：R74[医药卫生—神经病学与精神病学]