THALAMUS

作品数：66被引量：87H指数：4
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Neural circuit mechanisms of epilepsy:Maintenance of homeostasis at the cellular,synaptic,and neurotransmitter levels
《Neural Regeneration Research》2026年第2期455-465,共11页Xueqing Du Yi Wang Xuefeng Wang Xin Tian Wei Jing 
supported by Basic Research Programs of Science and Technology Commission Foundation of Shanxi Province,No.20210302123486(to WJ).
Epilepsy,a common neurological disorder,is characterized by recurrent seizures that can lead to cognitive,psychological,and neurobiological consequences.The pathogenesis of epilepsy involves neuronal dysfunction at th...
关键词：chemical genetics hippocampus literature review neural circuits NEUROTRANSMITTER OPTOGENETICS pathogenesis SEIZURE synapses THALAMUS 
Single‑Neuron Reconstruction of the Macaque Primary Motor Cortex Reveals the Diversity of Neuronal Morphology
《Neuroscience Bulletin》2025年第3期525-530,共6页Siyu Li Yan Shen Yefei Chen Zexuan Hong Lewei Zhang Lufeng Ding Chao‑Yu Yang Xiaoyang Qi Quqing Shen Yanyang Xiao Pak‑Ming Lau Zhonghua Lu Fang Xu Guo‑Qiang Bi 
supported by the National Key R&D Program of China(2020YFE0205900 and 2022YEF0203200);the STI 2030-Major Project(2021ZD0200104 and 2022ZD0205203);the Shenzhen Science and Technology Program(RCYX20210706092100003,RCBS20221008093311027,and JCYJ20210324102006018);the Youth Innovation Promotion Association CAS(2022367);the Shenzhen Technological Research Center for Primate Translational Medicine grant(XMHT20220104005).
Dear Editor,The primary motor cortex,also known as MOp in rodents,F1,or M1 in primates[1],plays a crucial role in autonomous motor control.It is interconnected with other motor control structures such as the basal gan...
关键词：habit formation autonomous motor controlit morphology action selectionmotor corticostriatal system NEURON basal gangliathalamusand primary motor cortexalso 
Aberrant outputs of cerebellar nuclei and targeted rescue of social deficits in an autism mouse model
《Protein & Cell》2024年第12期872-888,共17页Xin-Yu Cai Xin-Tai Wang Jing-Wen Guo Fang-Xiao Xu Kuang-Yi Ma Zhao-Xiang Wang Yue Zhao Wei Xie Martijn Schonewille Chris De Zeeuw Wei Chen Ying Shen 
supported by grants from the STI2030-Major Projects (2021ZD0204000);Key Strategic Science and Technology Cooperation Project (2023YFE0206800) of the Ministry of Science and Technology of China;the National Natural Science Foundation of China (81625006, 31820103005, 32000692);Zhejiang Province Natural Science Foundation of China (LZ24C090003 and LY21C090003);the Science and Technology Programme of Hangzhou Municipaility (20190101A10);the Key Realm R&D Program of Guangdong Province (2019B030335001);the Netherlands Organization for Scientific Research (NWO-ALW 824.02.001);the Dutch Organization for Medical Sciences (Zon MW 91120067);Medical Neuro-Delta (MD 01092019-31082023);INTENSE LSH-NWO (TTW/00798883);ERC-adv (GA-294775);ERC-POC (737619 and 768914)
The cerebellum is heavily connected with other brain regions,sub-serving not only motor but also nonmotor functions.Genetic mutations leading to cerebellar dysfunction are associated with mental diseases,but cerebella...
关键词：CEREBELLUM THALAMUS MIDBRAIN large-scale tracing AUTISM 
Map activation of various brain regions using different frequencies of electroacupuncture ST36,utilizing the FosCreER strategy
《Acupuncture and Herbal Medicine》2024年第3期386-398,共13页Zi Guo Naixuan Wei Ru Ye Tiancheng Sun Shuang Qiu Xiaomei Shao Xiaochang Ge Lu Guan Junfan Fang Jianqiao Fang Junying Du 
supported by the National Natural Science Fund of China(82374561,82174490,81873360);the Zhejiang Medical and Health Science and Technology Program(2021RC098);the Research Project of Zhejiang Chinese Medical University(2022JKZKTS44).
Objective:Electroacupuncture(EA)is an alternative treatment option for pain.Different frequencies of EA have different painrelieving effects;however,the central mechanism is still not well understood.Methods:The Fos2A...
关键词：AMYGDALA CORTEX EA-TRAPed neurons ELECTROACUPUNCTURE Frequency HYPOTHALAMUS THALAMUS 
Developmental Impairments of Synaptic Refinement in the Thalamus of a Mouse Model of Fragile X Syndrome
《Neuroscience Bulletin》2024年第4期439-450,共12页Xiaotong Wu Yali Liu Xiaomeng Wang Lu Zheng Libiao Pan Hao Wang 
supported by grants from the National Natural Science Foundation of China(32171014,31970940,31671100,31622027);the Zhejiang Provincial Natural Science Foundation of China(LR18H090001);the Non-profit Central Research Institute Fund of the Chinese Academy of Medical Sciences(2018PT31041);the Program for Introducing Talents in Discipline to Universities,the Fundamental Research Funds for Central Universities(2021FZZX001-37).
While somatosensory over-reactivity is a common feature of autism spectrum disorders such as fragile X syndrome(FXS),the thalamic mechanisms underlying this remain unclear.Here,we found that the developmental eliminat...
关键词：Fragile X syndrome Synaptic refinement VPm Sensory over-reactivity 
Photochemically induced thalamus infarction impairs cognition in a mouse model被引量：1
《Stroke & Vascular Neurology》2023年第6期444-452,I0001,I0002,共11页Chen Zhang Shiping Li Yongjun Wang Jiong Shi 
the Beijing Municipal Science&Technology Commission(Grant No.D171100003017002);National Key R&D Program of China(Grant No.2018YFC1312903);Strategic Priority Research Program of the Chinese Academy of Sciences(XDB39000000);National Science and Technology Major Project(Grant No.2017ZX09304018).
Background Small subcortical infarcts account for up to 25%of ischaemic strokes.Thalamus is one of the subcortical structures that commonly manifest with lacunar infarcts on MRI of the brain.Studies have shown that th...
关键词：INFARCTION THALAMUS IMPAIRED 
A direct spino-cortical circuit bypassing the thalamus modulates nociception被引量：2
《Cell Research》2023年第10期775-789,共15页Bing Cai Dan Wu Hong Xie Yan Chen Huadong Wang Sen Jin Yuran Song Anan Li Shiqi Huang Sashuang Wang Yingjin Lu Lan Bao Fuqiang Xu Hui Gong Changlin Li Xu Zhang 
supported by the National Natural Science Foundation of China(32030050 and 32192413);Guangdong High Level Innovation Research Institute(2021B0909050004);CAMS Innovation Fund for Medical Sciences(2019-I2M-5-082),and Shenzhen Sanming Project.
Nociceptive signals are usually transmitted to layer 4 neurons in somatosensory cortex via the spinothalamic-thalamocortical pathway.The layer 5 corticospinal neurons in sensorimotor cortex are reported to receive the...
关键词：BYPASS CORTEX MORPHOLOGICAL 
Some Characteristics of Neurons in the Reticular Nucleus of the Thalamus (Preliminary Data)
《Journal of Behavioral and Brain Science》2023年第3期45-54,共10页Zakaria I. Nanobashvili Irine G. Bilanishvili Irine G. Vashakidze Maia G. Barbakadze Megi G. Dumbadze Nadejda A. Khizanishvili 
Our general understanding of the function of neurons is that dendrites receive information that is relayed to the axon, where action potentials are initiated and propagated to eventually trigger neurotransmitter relea...
关键词：THALAMUS NEURON Dendrite Potentials Cat 
Release of Endogenous Brain-derived Neurotrophic Factor into the Lateral Entorhinal Cortex from the Paraventricular Thalamus Ameliorates Social Memory Deficits in a Mouse Model of Alzheimer’s Disease被引量：2
《Neuroscience Bulletin》2022年第11期1425-1430,共6页Yun‑Long Xu Lin Zhu Zi‑Jun Chen Xiao‑Fei Deng Pei‑Dong Liu Shan Li Bing‑Chun Lin Chuan‑Zhong Yang Wei Xu Kui-Kui Zhou Ying‑Jie Zhu 
the Frontier Research Program of Biol and Laboratory(Guangzhou Regenerative Medicine and Health Guangdong Laboratory)(2018GZR110105006);the National Natural ScienceFoundation of China(31900735,82171492,and 81922024);the Science,Technology and Innovation Commission of Shenzhen Municipality(RCJC 20200714114556103 and ZDSYS20190902093601675).
Dear Editor,Alzheimer's disease(AD)is one of the most devastating neurodegenerative disorders and the most common form of dementia.Synaptic loss is a hallmark of AD pathology and exacerbates cognitive impairment[1].Sy...
关键词：ALZHEIMER pathology IMPAIRMENT 
Altered asymmetries of resting-state MRI in the left thalamus of first-episode schizophrenia被引量：3
《Chronic Diseases and Translational Medicine》2022年第3期207-217,共11页Sha Liu Zhenglong Guo Hongbao Cao Hong Li Xiaodong Hu Long Cheng Jianying Li Ruize Liu Yong Xu 
National Natural Science Foundation of China(Grant/Award Number:81701326);National Key Research and Development Program of China(Grant/Award Number:2016YFC1307004);Multidisciplinary Team for Cognitive Impairment of Shanxi Science and Technology Innovation Training Team(Grant/Award Number:201705D131027);Special Project of Scientific Research Plan Talents of Shanxi Provincial Health Commission(Grant/Award Number:2020081);Shanxi Provincial Science and Technology Achievements Transformation and Guidance Project(Grant/Award Numbers:201904D131020,81971601);Shanxi Province Overseas Students Science and Technology Activity Funding Project(Grant/Award Number:20200038)。
Background:Schizophrenia(SCZ)is a complex psychiatric disorder associated with widespread alterations in the subcortical brain structure.Hemispheric asymmetries are a fundamental organizational principle of the human ...
关键词：asymmetry gray matter volume resting-state fMRI SCHIZOPHRENIA THALAMUS 
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