For many decades,Alzheimer's disease research has primarily focused on impairments within cortical and hippocampal regions,which are thought to be related to cognitive dysfunctions such as memory and language deficits...
supported by grants from the National Key R&D Program of China(2021ZD0202803);the National Natural Science Foundation of China(U21A20418).
Fear,as a type of psychological state and negative emotion,represents a common reflex towards the presence or imminence of danger.Clinically,fear-related disorders such as panic disorder and anxiety disorder can lead ...
supported financially by the National Natural Science Foundation of China,No.82071272(to YZ).
Brain-derived neurotrophic factor is a key factor in stress adaptation and avoidance of a social stress behavioral response.Recent studies have shown that brain-derived neurotrophic factor expression in stressed mice ...
supported by the STI2030-Major Projects(2021ZD0203800 and 2022ZD0205100);the National Natural Science Foundation of China(32430043,32371106 and U20A2017);the Guangdong Basic and Applied Basic Research Foundation(2020A1515111118 and 2022A1515010134);the Youth Innovation Promotion Association of the Chinese Academy of Sciences(2017120);the Interdisciplinary Innovation Team of the Chinese Academy of Sciences(JCTD-2021-06);the Shenzhen-Hong Kong Institute of Brain Science-Shenzhen Fundamental Research Institutions(NYKFKT2019009);the Shenzhen Technological Research Center for Primate Translational Medicine(XMHT20220104005);the Key Research and Development Program of Guangdong Province(2023B0303010004)and the Fundamental Research Funds for the Central Universities.
The ability to rapidly recognize basic facial emotions(e.g.fear)is crucial for social interactions and adaptive functioning.To date,the origin of facial-emotion-recognition ability remains equivocal.Using a classical ...
supported by the National Natural Science Fund of China(82374561,82174490,81873360);the Zhejiang Medical and Health Science and Technology Program(2021RC098);the Research Project of Zhejiang Chinese Medical University(2022JKZKTS44).
Objective:Electroacupuncture(EA)is an alternative treatment option for pain.Different frequencies of EA have different painrelieving effects;however,the central mechanism is still not well understood.Methods:The Fos2A...
This work is supported by the National Natural Science Foundation of China(grant/award numbers:81871430,81871426,U22A20303,82260359);Hebei Provincial Natural Science Foundation(grant/award numbers:H2020206263,H2020206625);STI2030-Major Projects Program(grant/award number:2022ZD0214500).
To the editor:It is commonly reported that people with insomnia often experience comorbid emotional disorders,such as mood and anxiety disorders.12 A study found that fragmented rapid eye movement(REM)sleep in individ...
supported by the grants from the Natural Science Foundation of Beijing Municipality(Grant No.:7212185);the Scientific and Technological Innovation project of China Academy of Chinese Medical Sciences(Grant No.:CI2021A03808);the National Natural Science Foundation of China(Grant Nos.:82330124,81974526,and 82274176);the Innovation Team and Talents Cultivation Program of the National Administration of Traditional Chinese Medicine,China(Program No.:ZYYCXTD-C-202002);the Special Project for Training Outstanding Young Scientific and Technological Talents(innovative type)of Necessary Scientific Research Business Expenses of China Academy of Chinese Medical Sciences(Project Nos.:ZZ13-YQ-051,and ZZ15-YQ-063);the Fundamental Research Funds for the Central public welfare research institutes(Grant No.:ZXKT21010).
Nowadays,roughly 603.7 million people are bothered by obesity[1].More seriously,obesity brings inflammation to the peripheral and central nervous system,which compromises the comorbidity of obesity,major depression[2]...
supported by the National Natural Science Foundation of China(Nos.82071516,32171065,91949105,and 81771227);the Innovation Capability Support Program of Shannxi Province in China(No.2020TD-037);the Fundamental Research Funds for the Central Universities(Nos.GK202105001,GK202205019,and CK202205022),China.
5-Hydroxytryptamine(5-HT)type 3 receptor(5-HT_(3)R)is the only type of ligand-gated ion channel in the 5-HT receptor family.Through the high permeability of Na+,K+,and Ca2+and activation of subsequent voltage-gated ca...
Mental disorders are a group of diseases with changes in cognition,emotion,behavior,and other aspects,which may be accompanied by painful experience or functional impairment.The cognition,emotion,and behavior change m...
supported by the National Natural Science Foundation of China(U20A2017 and 31830037);Guangdong Basic and Applied Basic Research Foundation(2020A1515010785,2020A1515111118,and 2022A1515010134);the Youth Innovation Promotion Association of the Chinese Academy of Sciences(2017120);the Shenzhen-Hong Kong Institute of Brain Science-Shenzhen Fundamental Research Institutions(NYKFKT2019009);Shenzhen Technological Research Center for Primate Translational Medicine(F-2021-Z99-504979);the Strategic Research Program of the Chinese Academy of Sciences(XDBS01030100 and XDB32010300);Scientific and Technological Innovation 2030(2021ZD0204300);the Fundamental Research Funds for the Central Universities.
Integrating multisensory inputs to generate accurate perception and guide behavior is among the most critical functions of the brain.Subcortical regions such as the amygdala are involved in sensory processing includin...