GLUTAMATE

作品数:334被引量:1017H指数:14
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相关领域:医药卫生更多>>
相关作者:潘小平刘国卿吴娟赵晓宁张祖暄更多>>
相关机构:复旦大学上海医学院中国药科大学南京大学中国人民解放军总医院更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划北京市自然科学基金国家教育部博士点基金更多>>
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Synaptic and synchronic impairments in subcortical brain regions associated with early non-cognitive dysfunction in Alzheimer's disease
《Neural Regeneration Research》2026年第1期248-264,共17页Nicolás Riffo-Lepe Juliana González-Sanmiguel Lorena Armijo-Weingart Paulina Saavedra-Sieyes David Hernandez Gerson Ramos Loreto S.San Martín Luis G.Aguayo 
supported by ANID/CONICYT Fondecyt Regular 1221080(to LGA);Fondecyt Postdoctoral fellow 3210260(to LAW);ANID PhD fellowship 21202521(to NRL);21211228(to JGS);21211758(to PSS)and 21230078(to DH)。
For many decades,Alzheimer's disease research has primarily focused on impairments within cortical and hippocampal regions,which are thought to be related to cognitive dysfunctions such as memory and language deficits...
关键词:Alzheimer's disease AMPA receptors AMYGDALA epilepsy gamma-aminobutyric acid GLUTAMATE hippocampus NEURODEGENERATION neuronal excitability N-methyl-D-aspartate receptors non-cognitive nucleus accumbens 
Glucocorticoid receptor signaling in the brain and its involvement in cognitive function
《Neural Regeneration Research》2025年第9期2520-2537,共18页Chonglin Su Taiqi Huang Meiyu Zhang Yanyu Zhang Yan Zeng Xingxing Chen 
supported by the National Natural Science Foundation of China,No.82371444(to YZ);the Natural Science Foundation of Hubei Province,No.2022CFB216(to XC);the Key Research Project of Ministry of Science and Technology of China,No.2022ZD021160(to YZ)。
The hypothalamic-pituitary-adrenal axis regulates the secretion of glucoco rticoids in response to environmental challenges.In the brain,a nuclear receptor transcription fa ctor,the glucocorticoid recepto r,is an impo...
关键词:brain-derived neurotrophic factor calcium signaling glucocorticoid receptor GLUCOCORTICOID glutamate transmission hypothalamic-pituitary-adrenal axis long-term potentiation neurocognitive disorders NEUROPLASTICITY stress 
Increased excitatory amino acid transporter 2 levels in basolateral amygdala astrocytes mediate chronic stress–induced anxiety-like behavior
《Neural Regeneration Research》2025年第6期1721-1734,共14页Xirong Xu Shoumin Xuan Shuai Chen Dan Liu Qian Xiao Jie Tu 
supported by the National Natural Science Foundation of China,Nos.32371070 (to JT),31761163005 (to JT),32100824 (to QX);the Shenzhen Science and Technology Program,Nos.RCBS20210609104606024 (to QX),JCY20210324101813035 (to DL);the Guangdong Provincial Key S&T Program,No.2018B030336001 (to JT);the Key Basic Research Program of Shenzhen Science and Technology Innovation Commission,Nos.JCYJ20200109115405930 (to JT),JCYJ20220818101615033 (to DL),JCYJ20210324115811031 (to QX),JCYJ20200109150717745 (to QX);Shenzhen Key Laboratory of Neuroimmunomodulation for Neurological Diseases,No.ZDSYS20220304163558001 (to JT);Guangdong Provincial Key Laboratory of Brain Connectome and Behavior,No.2023B1212060055 (to JT);the China Postdoctoral Science Foundation,No.2021M693298 (to QX)。
The conventional perception of astrocytes as mere supportive cells within the brain has recently been called into question by empirical evidence, which has revealed their active involvement in regulating brain functio...
关键词:ANXIETY ASTROCYTES basolateral amygdala behavior dihydrokainic acid excitatory amino acid transporter 2 fiber photometry GLUTAMATE LDN-212320 TRANSPORTER 
Effect of sodium laurate on the properties of sodium lauroyl glutamate
《日用化学工业(中英文)》2025年第4期446-452,共7页Guofang Gao Yadan Feng Ziwei Diao Yongqiang Sun Zhiyong Hu Hailin Zhu 
山西省自然科学基金面上项目(202103021224207);中北大学研究生科技立项(20231926)。
In this paper,the effect of sodium laurate(SL)on the properties of sodium lauroyl glutamate(SLG),such as surface activity,foam,wetting,emulsification,and resistance to hard water,has been systematically investigated.T...
关键词:sodium lauroyl glutamate sodium laurate surface activity emulsification properties wetting properties 
On the functions of astrocyte-mediated neuronal slow inward currents被引量:2
《Neural Regeneration Research》2024年第12期2602-2612,共11页Balázs Pál 
funded by the National Research Developm ent and Innovation Office (NKFIH-K1468 73) (to BP)。
Slow inward currents are known as neuronal excitatory currents mediated by glutamate release and activation of neuronal extra synaptic N-met hyl-D-aspartate receptors with the contribution of astrocytes.These events a...
关键词:ASTROCYTE cortical spreading depolarization gliotransmission GLUTAMATE neural synchronization NMDA receptor paroxysmal depolarizational shift slow inward current 
Retraction notice to“L-Leucine stimulates glutamate dehydrogenase activity and Glutamate synthesis by regulating mTORC1/SIRT4 pathway in pig liver”[Animal Nutrition 4(2018)329e338]
《Animal Nutrition》2024年第4期488-488,共1页Tongxin Wang Weilei Yao Qiongyu He Yafei Shao Ruilong Zheng Feiruo Huang 
This article has been retracted:please see Elsevier Policy on Article Withdrawal(https://www.elsevier.com/about/policies/articlewithdrawal).This article has been retracted at the request of the Editors-in-Chief,follow...
关键词:PLEASE ELSEVIER ANIMAL 
The glutamate receptor gene GLR3.3:A bridge of calciummediated root development in poplar
《Horticultural Plant Journal》2024年第6期1449-1462,共14页Yi An Ya Geng Yu Liu Xiao Han Lichao Huang Wei Zeng Jin Zhang Mengzhu Lu 
supported by the National Natural Science Foundation of China(Grant Nos.32371902,31901327);National Key Research and Development Program of China(Grant Nos.2019YFE0119100,2021YFD2200205);Overseas Expertise Introduction Project for Discipline Innovation(111 Project D18008);The researches foundation of Zhejiang A&F University(Grant No.2018FR013)。
Poplar is one of the fastest-growing temperate trees in the world and is widely used in ornamental horticulture for shade.The root is essential for tree growth and development and its utilization potential is huge.Cal...
关键词:Glutamate receptor CALCIUM Root development Lateral root POPLAR 
Endoplasmic reticulum adenylate transporter activity affects amino acid metabolism under photorespiratory conditions
《The Crop Journal》2024年第6期1633-1644,共12页Jieni Li Yuxin Song Xin Luan Yajun Gou Tao Xie Yu Hong Na Liu Yao Su Xueli Fu Tianxiu Zhong Shu Chen Yuexiong Zhang Gang Qin Xiang-Qian Zhang 
supported by the National Natural Science Foundation of China (31671594);Guangdong Basic and Applied Basic Research Foundation (2024A1515011098,2021A1515012482).
The involvement of the endoplasmic reticulum(ER)-localized adenylate transporter1(ER-ANT1)in photorespiratory metabolism has been established,yet its precise physiological function remains uncertain.Rice er-ant1 mutan...
关键词:Endoplasmic reticulum PHOTORESPIRATION Amino acid Glutamate/alanine aminotransferase ER-ANT1 
Ruxolitinib improves the inflammatory microenvironment,restores glutamate homeostasis,and promotes functional recovery after spinal cord injury被引量:1
《Neural Regeneration Research》2024年第11期2499-2512,共14页Jiang Cao Xiao Yu Jingcheng Liu Jiaju Fu Binyu Wang Chaoqin Wu Sheng Zhang Hongtao Chen Zi Wang Yinyang Xu Tao Sui Jie Chang Xiaojian Cao 
supported by the National Natural Science Foundation of China,No.82272484(to XC).
The inflammatory microenvironment and neurotoxicity can hinder neuronal regeneration and functional recovery after spinal cord injury.Ruxolitinib,a JAK-STAT inhibitor,exhibits effectiveness in autoimmune diseases,arth...
关键词:astrocytes EAAT2 EXCITOTOXICITY glutamate homeostasis JAK-STAT pathway locomotor function NEUROTOXICITY RUXOLITINIB spinal cord injury transcriptome analysis 
p38 MAPK inhibitor SB202190 suppresses ferroptosis in the glutamate-induced retinal excitotoxicity glaucoma model被引量:2
《Neural Regeneration Research》2024年第10期2299-2309,共11页Lemeng Feng Chao Wang Cheng Zhang Wulong Zhang Weiming Zhu Ye He Zhaohua Xia Weitao Song 
supported by the National Natural Science Foundation of China,Nos.81974132,81770927;Hunan Provincial Health Commission,No.20220702839;the Natural Science Foundation of Hunan Province of China,No.2022JJ30076;National Key R&D Program of China,No.2021YFA1101202(all to WS)。
Glutamate excitotoxicity has been shown to play an important role in glaucoma, and glutamate can induce ferroptosis. The p38 mitogenactivated protein kinase(MAPK) pathway inhibitor SB202190 has a potential ability to ...
关键词:ferroptosis GLAUCOMA glutamate excitotoxicity p38 MAPK retinal ganglion cell SB202190 
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