CALCIUM

作品数:1041被引量:2629H指数:18
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相关领域:医药卫生更多>>
相关作者:赵翔张骁崔宗杰李英王帅更多>>
相关机构:中南大学中国农业大学中山医科大学首都医科大学更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划中国博士后科学基金国家高技术研究发展计划更多>>
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Calcium-sensitive protein MLC1 as a possible modulator of the astrocyte functional state
《Neural Regeneration Research》2025年第7期2008-2010,共3页Elena Ambrosini Angela Lanciotti Maria Stefania Brignone 
supported by funds from the Italian Ministry of Health,Ricerca Finalizzata,(Grant N.GR-2013-02355882 and GR-2021-12373946 to AL);5x1000 Project of the Istituto Superiore di Sanità(Project code:ISS5x1000_21-949432e8c9be to AL);the European Union–NextGeneration EU through the Italian Ministry of University and Research under PNRR-M4C2-I1.3 Project PE_00000019“HEAL ITALIA”to EA(CUP I83C22001830006)。
Astrocytes,the main population of glial cells in the central nervous system(CNS),exert essential tasks for the control of brain tissue homeostasis,supporting neuron and other glial cell activity from the developmental...
关键词:alterations MODULATOR MAINTAIN 
Comparison of effects of calcium and chlorogenic acid intervention on bone and intestinal injury in cadmium-exposed growing rats
《Food and Health》2025年第2期24-34,共11页Yu-Na Kan Xiao-Wei Wang Hui-Fang Chen Xiao-Jiao Gao Xiao Huang Jia-Ming Xie 
supported by Guizhou Provincial Basic Research Program(Natural Science)(Qiankeheji-ZK[2021]General 497);Guizhou Health and Wellness Commission Science and Technology Fund Project(2024-247);Guizhou University of Traditional Chinese Medicine Academic Seedling Program(Guizhou Kehe Academic Seedling[2023]-35),The Second Affiliated Hospital of Guizhou University of Traditional Chinese Medicine Institutional Research Grants(GZEYK[2020-34]).
Background:Cadmium(Cd)exposure disrupts bone microstructure and elevates osteoporosis risk,warranting innovative functional food development to alleviate its toxic effects.This study evaluated the protective effects o...
关键词:CADMIUM CALCIUM chlorogenic acid bone microstructure gut microbiota oxidative stress 
NECAB family of neuronal calcium-binding proteins in health and disease
《Neural Regeneration Research》2025年第5期1236-1243,共8页Diones Bueno Michael K.E.Schafer Sudena Wang Michael J.Schmeisser Axel Methner 
supported by the Deutsche Forschungsgemeinschaft (ME1922/14-1) to AM。
The N-terminal EF-hand calcium-binding proteins 1–3(NECAB1–3) constitute a family of predominantly neuronal proteins characterized by the presence of at least one EF-hand calcium-binding domain and a functionally le...
关键词:CALCIUM EF hand MITOCHONDRIA nervous system signal transduction 
Intracellular calcium channels:Potential targets for type 2 diabetes mellitus?
《World Journal of Diabetes》2025年第4期37-47,共11页Jia-Xuan Zhu Zhao-Nan Pan Dan Li 
Supported by Calygene Biotechnology Inc.,No.XT[2016]008@。
Type 2 diabetes mellitus(T2DM)is a prevalent metabolic disorder.Despite the availability of numerous pharmacotherapies,a range of adverse reactions,including hypoglycemia,gastrointestinal discomfort,and lactic acidosi...
关键词:Ion channels AMP-activated protein kinase CALCIUM DIABETES Lactic acidosis 
Mechanism of action of Xipayimaizibizi oral liquid on outlet obstruction-induced overactive bladder:An integrated study
《Journal of Traditional Chinese Medical Sciences》2025年第1期86-99,共14页Menglu Wang Yang Yang Yuhang Du Jiamei Xie Yige Zhao Yongcheng An Ziyi Shan Shenyujun Wang Meng Hao Baosheng Zhao 
supported by the Natural Science Foundation in Xinjiang Uygur Autonomous Region(Urumqi,China,2023D01F38).
Objective:To observe the effect of Xipayimaizibizi oral liquid(XP)in an overactive bladder(OAB)experimental rat model and to explore its pharmacological mechanisms.Methods:Network pharmacology was used to explore the ...
关键词:Xipayimaizibizi oral liquid Overactive bladder Partial bladder outlet obstruction Muscarinic receptor Cholinergic synapse Calcium signaling pathway 
Transient receptor potential channels and calcium dysregulation: a pathogenic duo in Parkinson's disease
《Neural Regeneration Research》2025年第3期808-810,共3页Iqira Saeed Linlin Ma 
Parkinson's disease(PD) has a complex and multifactorial pathophysiology. Various studies, conducted both in pre-clinical models and PD patients, have reported a link between the disruption of calcium(Ca^(2+)) homeost...
关键词:HOMEOSTASIS CLINICAL subsequent 
Trace Element Concentrations in the Sera of Pregnant Women in Kisangani, Democratic Republic of Congo
《Journal of Biosciences and Medicines》2025年第2期218-229,共12页Likilo Osundja Jérémie Komanda Likwekwe Emmanuel Tshodi Bulanda Arsène Juakali Sihalikyolo Jean-Jeannot Buhendwa Mirindi Victor Katenga Bosunga Gédéon 
Introduction: During pregnancy, the increased demand for all the nutrients required for the development of the foetus means that the maternal stock of trace elements and minerals may become unbalanced if dietary intak...
关键词:Trace Element Zinc Copper SELENIUM CALCIUM Magnesium Pregnant Woman SERUM Kisangani 
A small molecule cryptotanshinone induces non-enzymatic NQO1-dependent necrosis in cancer cells through the JNK1/2/Iron/PARP/calcium pathway
《Acta Pharmaceutica Sinica B》2025年第2期991-1006,共16页Ying Hou Bingling Zhong Lin Zhao Heng Wang Yanyan Zhu Xianzhe Wang Haoyi Zheng Jie Yu Guokai Liu Xin Wang Jose M.Martin-Garcia Xiuping Chen 
supported by the Science and Technology Development Fund,Macao S.A.R(FDCT)(0070/2022/A2,005/2023/SKL,China);the National Natural Science Foundation of China(82173848);the Research Fund of University of Macao(MYRG2020-00053-ICMS,MYRG-GRG2023-00072-ICMS-UMDF,China);the Ministry of Education Frontiers Science Centre for Precision Oncology,University of Macao(SP2023-00001-FSCPO,China).
Human NAD(P)H:quinone oxidoreductase 1(NQO1)is a flavoenzyme expressed at high levels in multiple solid tumors,making it an attractive target for anticancer drugs.Bioactivatable drugs targeting NQO1,such asβ-lapacho...
关键词:NQO1 CRYPTOTANSHINONE Iron Ferroptosis NADþdepletion CALCIUM Targeted therapy Cancer 
STIM Proteins: The Gas and Brake of Calcium Entry in Neurons
《Neuroscience Bulletin》2025年第2期305-325,共21页Ksenia Skobeleva Guanghui Wang Elena Kaznacheyeva 
supported by grants from the Russian Science Foundation(23-44-00054);the National Natural Science Foundation of China(32261133525).
Stromal interaction molecules(STIM)s are Ca^(2+)sensors in internal Ca^(2+)stores of the endoplasmic reticulum.They activate the store-operated Ca^(2+)channels,which are the main source of Ca^(2+)entry in non-excitabl...
关键词:STIM1 STIM2 CALCIUM NEURONS BRAIN Calcium entry Calcium channels 
Risk factors for developing osteoporosis in diabetic kidney disease and its correlation with calcium-phosphorus metabolism,FGF23,and Klotho
《World Journal of Diabetes》2025年第1期49-57,共9页Fan Yang Yan Wu Wei Zhang 
BACKGROUND The progression of diabetic kidney disease(DKD)affects the patient’s kidney glomeruli and tubules,whose normal functioning is essential for maintaining normal calcium(Ca)and phosphorus(P)metabolism in the ...
关键词:Diabetic kidney disease OSTEOPOROSIS Calcium-phosphorus metabolism FGF23 KLOTHO 
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