OSTEOPOROSIS

作品数：639被引量：2466H指数：22
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相关机构：浙江大学医学院附属邵逸夫医院广州中医药大学第一附属医院北京积水潭医院第二军医大学更多>>
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The relationship between geriatric nutritional risk index and cardiovascular disease and all-cause mortality in patients with osteoporosis and osteopenia
《Journal of Geriatric Cardiology》2025年第4期443-454,共12页Sheng-Han WANG Hang YIN Shan-Shan ZHOU 
BACKGROUND The correlation between geriatric nutritional risk index(GNRI)and the prognosis of patients with osteoporosis or osteopenia has not been studied.This study aims to explore the relationship between GNRI and ...
关键词：OSTEOPOROSIS All Cause Mortality multivariable cox re cardiovascular disease cvd OSTEOPENIA geriatric nutritional risk index gnri Geriatric Nutritional Risk Index Cardiovascular Disease 
Accuracy of artificial intelligence in prediction of osteoporotic fractures in comparison with dual-energy X-ray absorptiometry and the Fracture Risk Assessment Tool: A systematic review
《World Journal of Orthopedics》2025年第4期51-57,共7页Mir Sadat-Ali Bandar A Alzahrani Turki S Alqahtani Musaad A Alotaibi Abdallah M Alhalafi Ahmed A Alsousi Abdullah M Alasiri 
BACKGROUND Osteoporotic fractures,whether due to postmenopausal or senile causes,impose a significant financial burden on developing countries and diminish quality of life.Recent advancements in artificial intelligenc...
关键词：Artificial intelligence OSTEOPOROSIS PREDICTION Fragility fractures 
Comparative analysis of the safety and efficacy of fenestrated pedicle screw with cement and conventional pedicle screw with cement in the treatment of osteoporotic vertebral fractures:A meta-analysis
《Chinese Journal of Traumatology》2025年第2期101-112,共12页Li Cao Hong-Jie Xu Yi-Kang Yu Huan-Huan Tang Bo-Hao Fang Ke Chen 
Zhejiang Traditional Chinese Medicine Science and Technology Program Project(Project No.:2023ZL429).
Purpose:Bone cement-reinforced fenestrated pedicle screws(FPSs)have been widely used in the internal fixation and repair of the spine with osteoporosis in recent years and show significant improvement in fixation stre...
关键词：Pedicle screw Internal fixation Bone cement strengthening Bone cement leakage OSTEOPOROSIS COMPLICATION META-ANALYSIS 
Lycium barbarum L.-Derived miR162a Functions on Osteoporosis Through Directly Promoting Osteoblast Formation
《Engineering》2025年第3期162-171,共10页Chunyan Gu Xichao Yu Xiaozhu Tang Leilei Gong Jingquan Tan Yuanjiao Zhang Huili Zheng Ze Wang Chenqian Zhang Yejin Zhu Zuojian Zhou Heming Yu Kai Xu Jinao Duan Xiaosong Gu Ye Yang 
supported by Key Project of Jiangsu Province’s Administration of Traditional Chinese Medicine(ZD202203);Jiangsu Province’s Innovation Program(JSSCTD202142);a project funded by the Priority Academic Program Development of Jiangsu Higher Education Institutions(traditional Chinese medicine).
Traditional Chinese medicine(TCM)can help prevent or treat diseases;however,there are few studies on the active substances of TCM.For example,Lycium barbarum L.has been proven to be effective in treating osteoporosis ...
关键词：Traditional Chinese medicine Lycium barbarum L. miR162a OSTEOPOROSIS Nuclear receptor corepressor Transgenic plants 
Cross-talks between osteoporosis and gut microbiome
《World Journal of Orthopedics》2025年第3期11-27,共17页Shiva Shankar Jha Naveen Jeyaraman Madhan Jeyaraman Swaminathan Ramasubramanian Sathish Muthu Gabriel Silva Santos Lucas Furtado da Fonseca JoséFábio Lana 
The gut microbiome comprises a vast community of microbes inhabiting the human alimentary canal,playing a crucial role in various physiological functions.These microbes generally live in harmony with the host;however,...
关键词：MICROBIOME DYSBIOSIS OSTEOPOROSIS PREBIOTICS Probiotics Inflammation BILE Vitamin D Calcium 
Cyclodextrin host-guest complex to facilitate sinomenine-based osteoporosis therapy
《World Journal of Stem Cells》2025年第3期139-143,共5页Meng-Qin Guo Ping Hu Zheng-Wei Huang 
Supported by Guangdong Basic and Applied Basic Research Foundation,No.2024A1515011236;General Program of Administration of Traditional Chinese Medicine of Guangdong Province,No.20241071.
Xiao et al reported on the natural product sinomenine(SIN),which is a traditional Chinese medicine for treating osteoporosis via its modulation of autophagy;however,SIN was dissolved in dimethyl sulfoxide prior to adm...
关键词：SINOMENINE CYCLODEXTRIN OSTEOPOROSIS AUTOPHAGY SOLUBILIZATION 
SP7 transcription factor ameliorates bone defect healing in low-density lipoprotein receptor-related protein 5(LRP5)-dependent osteoporosis mice
《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》2025年第3期254-268,共15页Yue XI Qifeng JIANG Wei DAI Chaozhen CHEN Yang WANG Xiaoyan MIAO Kaichen LAI Zhiwei JIANG Guoli YANG Ying WANG 
Loss-of-function variants of low-density lipoprotein receptor-related protein 5(LRP5)can lead to reduced bone formation,culminating in diminished bone mass.Our previous study reported transcription factor osterix(SP7)...
关键词：Gene therapy Low-density lipoprotein receptor-related protein 5(LRP5) Transcription factor osterix(SP7) OSTEOPOROSIS Defect healing 
Oxidative stress-induced circSOD2 inhibits osteogenesis through sponging miR-29b in metabolic-associated fatty liver disease
《World Journal of Gastroenterology》2025年第9期68-82,共15页Liang-Ping Li Xiao-Ying Chen Hong-Bo Liu Yi Zhu Min-Jie Xie Yong-Jian Li Meng Luo Mugahed Albahde Hong-Yu Zhang Jian-Ying Lou 
Supported by the National and Zhejiang Provincial Administration of Traditional Chinese Medicine Co-construction Project,No.GZYZJ-KJ-24080;the Medical Science and Technology Project of Zhejiang Province,No.2024XY228.
BACKGROUND Metabolic-associated fatty liver disease(MAFLD)is characterized by lipid accumulation in hepatocytes and is closely associated with oxidative stress.Increasing clinical evidence indicates that MAFLD is link...
关键词：Circular RNAs MICRORNAS Oxidative stress OSTEOGENESIS Non-alcoholic fatty liver disease OSTEOPOROSIS 
Additional role of low-density lipoprotein cholesterol on the risk of osteoporosis in men with or without coronary heart disease:a real-world longitudinal study
《Journal of Geriatric Cardiology》2025年第2期219-228,共10页Jing ZENG Zi-Mo PAN Ting LI Ze-Yu CHEN Xiao-Yan CAI Mei-Liang GONG Xin-Li DENG Sheng-Shu WANG Nan LI Miao LIU Chun-Lin LI 
supported by the Multi-center RCT Clinical Project of the National Clinical Research Center for Geriatric Diseases,Chinese PLA General Hospital(NCRCGPLAGH-2023001);the Beijing Nova Program(No.20220484020);the Beijing Natural Science Foundation(No.7252181);the Capital’s Funds for Health Improvement and Research(No.2024-2G-5033).
BACKGROUND Early control of low-density lipoprotein cholesterol(LDL-C)is crucial for reducing the progress of cardiovascular disease.However,its additional role to the risk of primary osteoporosis in men with coronary...
关键词：OSTEOPOROSIS CORONARY LIPOPROTEIN 
Roles of lncRNA in the crosstalk between osteogenesis and angiogenesis in the bone microenvironment
《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》2025年第2期107-123,共17页Shihua ZHANG Jianmin GUO Yuting HE Zhi’ang SU Yao FENG Lan ZHANG Jun ZOU Xiquan WENG Yu YUAN 
supported by the National Natural Science Foundation of China(No.81901430);the Guangdong Basic and Applied Basic Research Foundation(No.2022A1515010379);the Science and Technology Projects in Guangzhou(No.2023A04J0555);the Guangdong Provincial Key Laboratory of Physical Activity and Health Promotion(No.2021B1212040014),China.
Bone is a highly calcified and vascularized tissue.The vascular system plays a vital role in supporting bone growth and repair,such as the provision of nutrients,growth factors,and metabolic waste transfer.Moreover,th...
关键词：Long noncoding RNA(lncRNA) OSTEOGENESIS Bone angiogenesis OSTEOPOROSIS Bone microenvironment 
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