supported by the Multi-center RCT Clinical Project of the National Clinical Research Center for Geriatric Diseases,Chinese PLA General Hospital(NCRCGPLAGH-2023001);the Beijing Nova Program(No.20220484020);the Beijing Natural Science Foundation(No.7252181);the Capital’s Funds for Health Improvement and Research(No.2024-2G-5033).
BACKGROUND Early control of low-density lipoprotein cholesterol(LDL-C)is crucial for reducing the progress of cardiovascular disease.However,its additional role to the risk of primary osteoporosis in men with coronary...
supported by grants fromthe National Key R&D Programof China(grant numbers 2022YFC2504900 and 2022YFC2504902);Beijing Natural Science Foundation(grant number Z200016);the National Natural Science Foundation of China(grant numbers 82101360 and 82171270).
Although essential for cardiovascular therapy,the pleiotropic effects of statins on ischemic stroke lack clinical evidence.This study examined the effects of statins beyond low-density lipoprotein cholesterol(LDL-C)le...
Supported by the Xuanwu Hospital Capital Medical University Science Program for Fostering Young Scholars,No.YC20220113;the Pilot Project for Public,No.Beijing Medical Research 2021-8.
BACKGROUND Dyslipidemia and type 2 diabetes mellitus(T2DM)are chronic conditions with substantial public health implications.Effective management of lipid metabolism in patients with T2DM is critical.However,there has...
the National Institutes of Health(NIH–National Institute of Dental and Craniofacial Research,grant R01DE031476)。
Apical periodontitis(AP)is a dental-driven condition caused by pathogens and their toxins infecting the inner portion of the tooth(i.e.,dental pulp tissue),resulting in inflammation and apical bone resorption affectin...
Canadian Institutes of Health Research (CIHR) (FDN-148396).
Metabolic health is highly dependent on intestinal and hepatic handling of dietary and endogenous lipids and lipoproteins.Disorders of lipid and lipoprotein metabolism are commonly observed in patients with insulin re...
Objective To explore the effects of Ginsenoside Re(G-Re) on oxidized low density lipoprotein (ox-LDL)-induced inflammatory response via mitogen-activated protein kinase/extracellular regulated protein kinases/nuclear ...
supported by the grants from the National Natural Science Foundation of China(No.81970753);the Wenzhou Science and Technology Bureau Foundation(No.ZY2021011).
Long noncoding RNAs(lncRNAs)have been widely proven to be involved in liver lipid homeostasis.Herein,we identify an upregulated lncRNA named lncRP11-675F6.3 in response to rapamycin treatment using a microarray in Hep...
This research was financially supported by the National Key R&D Program of China 2021YFA0805100;National Natural Science Foundation of China(Grant Nos.92268202,81830013,81970363,82270485,and 81770241);Guangdong Basic and Applied Basic Research Foundation(Grant 2019B1515120092);Science and Technology Planning Project of Guangzhou,China 202103000016;Sun Yat-sen University Clinical Research 5010 Program(2014002);the Program of National Key Clinical Specialties.Figures 7a,8d and Supplementary Fig.S14a were created with BioRender.com.
Normal high-density lipoprotein(nHDL)can induce angiogenesis in healthy individuals.However,HDL from patients with coronary artery disease undergoes various modifications,becomes dysfunctional(dHDL),and loses its abil...
Objective To assess the prevalence of metabolic syndrome(MS)and its relationship with hyperuricemia(HUA)in perimenopausal women in Anning city,Yunnan province.Methods This is a cross-sectional survey.In May 2021,a mul...
Introduction: This study was conducted in the University of Port Harcourt Teaching Hospital, with the sample analysis conducted in HMG Hospital private laboratory in Rivers State. Methodology: A random sampling techni...